Anticancer thiosemicarbazones: chemical properties, interaction with iron metabolism, and resistance development P Heffeter, VFS Pape, ÉA Enyedy, BK Keppler, G Szakacs, CR Kowol Antioxidants & redox signaling 30 (8), 1062-1082, 2019 | 170 | 2019 |
Investigation of chalcones and benzochalcones as inhibitors of breast cancer resistance protein K Juvale, VFS Pape, M Wiese Bioorganic & medicinal chemistry 20 (1), 346-355, 2012 | 140 | 2012 |
Design, synthesis and biological evaluation of thiosemicarbazones, hydrazinobenzothiazoles and arylhydrazones as anticancer agents with a potential to overcome multidrug resistance VFS Pape, S Tóth, A Füredi, K Szebényi, A Lovrics, P Szabó, M Wiese, ... European journal of medicinal chemistry 117, 335-354, 2016 | 108 | 2016 |
High-affinity peroxisome proliferator-activated receptor β/δ-specific ligands with pure antagonistic or inverse agonistic properties S Naruhn, PM Toth, T Adhikary, K Kaddatz, V Pape, S Dörr, G Klebe, ... Molecular pharmacology 80 (5), 828-838, 2011 | 58 | 2011 |
Identification and validation of compounds selectively killing resistant cancer: delineating cell line–specific effects from P-glycoprotein–induced toxicity A Füredi, S Tóth, K Szebényi, VFS Pape, D Türk, N Kucsma, L Cervenak, ... Molecular cancer therapeutics 16 (1), 45-56, 2017 | 49 | 2017 |
Comparative solution equilibrium studies of antitumor ruthenium (η 6-p-cymene) and rhodium (η 5-C 5 Me 5) complexes of 8-hydroxyquinolines O Dömötör, VFS Pape, NV May, G Szakács, ÉA Enyedy Dalton Transactions 46 (13), 4382-4396, 2017 | 47 | 2017 |
Impact of copper and iron binding properties on the anticancer activity of 8-hydroxyquinoline derived Mannich bases VFS Pape, NV May, GT Gál, I Szatmári, F Szeri, F Fülöp, G Szakács, ... Dalton Transactions 47 (47), 17032-17045, 2018 | 44 | 2018 |
The thiosemicarbazone Me2NNMe2 induces paraptosis by disrupting the ER thiol redox homeostasis based on protein disulfide isomerase inhibition S Hager, K Korbula, B Bielec, M Grusch, C Pirker, M Schosserer, L Liendl, ... Cell death & disease 9 (11), 1052, 2018 | 43 | 2018 |
Development of improved PPARβ/δ inhibitors PM Toth, S Naruhn, VFS Pape, S Dörr, G Klebe, R Müller, WE Diederich ChemMedChem 7 (1), 159-170, 2012 | 40 | 2012 |
Synthesis and characterization of the anticancer and metal binding properties of novel pyrimidinylhydrazone derivatives VFS Pape, D Türk, P Szabó, M Wiese, EA Enyedy, G Szakács Journal of inorganic biochemistry 144, 18-30, 2015 | 36 | 2015 |
High Copper Complex Stability and Slow Reduction Kinetics as Key Parameters for Improved Activity, Paraptosis Induction, and Impact on Drug-Resistant Cells of Anticancer … S Hager, VFS Pape, V Pósa, B Montsch, L Uhlik, G Szakács, S Tóth, ... Antioxidants & redox signaling 33 (6), 395-414, 2020 | 34 | 2020 |
Unshielding Multidrug Resistant Cancer through Selective Iron Depletion of P-Glycoprotein–Expressing Cells M Cserepes, D Türk, S Tóth, VFS Pape, A Gaál, M Gera, JE Szabó, ... Cancer Research 80 (4), 663-674, 2020 | 25 | 2020 |
Complex formation and cytotoxicity of Triapine derivatives: a comparative solution study on the effect of the chalcogen atom and NH-methylation ÉA Enyedy, NV May, VFS Pape, P Heffeter, G Szakács, BK Keppler, ... Dalton Transactions 49 (46), 16887-16902, 2020 | 23 | 2020 |
Structure–activity relationships of 8-hydroxyquinoline-derived Mannich bases with tertiary amines targeting multidrug-resistant cancer VFS Pape, R Palkó, S Tóth, MJ Szabó, J Sessler, G Dormán, EA Enyedy, ... Journal of Medicinal Chemistry 65 (11), 7729-7745, 2022 | 21 | 2022 |
Half-sandwich organometallic Ru and Rh complexes of (N, N) donor compounds: effect of ligand methylation on solution speciation and anticancer activity JP Mészáros, VFS Pape, G Szakács, G Németi, M Dénes, T Holczbauer, ... Dalton Transactions 50 (23), 8218-8231, 2021 | 17 | 2021 |
Relation of Metal-Binding Property and Selective Toxicity of 8-Hydroxyquinoline Derived Mannich Bases Targeting Multidrug Resistant Cancer Cells VFS Pape, A Gaál, I Szatmári, N Kucsma, N Szoboszlai, C Streli, F Fülöp, ... Cancers 13 (1), 154, 2021 | 10 | 2021 |
Influence of Post-Translational Modifications on Protein Identification in Database Searches F Bugyi, D Szabó, G Szabó, Á Révész, VFS Pape, E Soltész-Katona, ... ACS omega 6 (11), 7469-7477, 2021 | 9 | 2021 |
Identifying new topoisomerase II poison scaffolds by combining publicly available toxicity data and 2D/3D-based virtual screening A Lovrics, VFS Pape, D Szisz, A Kalászi, P Heffeter, C Magyar, G Szakács Journal of Cheminformatics 11 (1), 67, 2019 | 9 | 2019 |
Hydrogen peroxide production by epidermal dual oxidase 1 regulates nociceptive sensory signals A Pató, Á Donkó, D Kaszás, M Boros, L Bodrogi, G Várady, VFS Pape, ... Redox Biology 62, 102670, 2023 | 4 | 2023 |
Measuring peroxidasin activity in live cells using bromide addition for signal amplification VFS Pape, HA Kovács, I Szatmári, I Ugrai, B Szikora, I Kacskovics, Z May, ... Redox Biology 54, 102385, 2022 | 2 | 2022 |