Pre-treatment with metformin activates Nrf2 antioxidant pathways and inhibits inflammatory responses through induction of AMPK after transient global cerebral ischemia G Ashabi, L Khalaj, F Khodagholi, M Goudarzvand, A Sarkaki Metabolic brain disease 30, 747-754, 2015 | 245 | 2015 |
Alginate oligosaccharide protects against endoplasmic reticulum-and mitochondrial-mediated apoptotic cell death and oxidative stress SK Tusi, L Khalaj, G Ashabi, M Kiaei, F Khodagholi Biomaterials 32 (23), 5438-5458, 2011 | 209 | 2011 |
Activation of AMP-activated protein kinase by metformin protects against global cerebral ischemia in male rats: interference of AMPK/PGC-1α pathway G Ashabi, F Khodagholi, L Khalaj, M Goudarzvand, M Nasiri Metabolic brain disease 29, 47-58, 2014 | 148 | 2014 |
Metformin pretreatment enhanced learning and memory in cerebral forebrain ischaemia: the role of the AMPK/BDNF/P70SK signalling pathway N Ghadernezhad, L Khalaj, H Pazoki-Toroudi, M Mirmasoumi, G Ashabi Pharmaceutical biology 54 (10), 2211-2219, 2016 | 88 | 2016 |
Metformin improves anxiety-like behaviors through AMPK-dependent regulation of autophagy following transient forebrain ischemia A Sarkaki, Y Farbood, M Badavi, L Khalaj, F Khodagholi, G Ashabi Metabolic brain disease 30, 1139-1150, 2015 | 88 | 2015 |
Gemfibrozil pretreatment affecting antioxidant defense system and inflammatory, but not Nrf-2 signaling pathways resulted in female neuroprotection and male neurotoxicity in … F Mohagheghi, L Khalaj, A Ahmadiani, B Rahmani Neurotoxicity research 23, 225-237, 2013 | 54 | 2013 |
Cyclooxygenase (COX)-1 activity precedes the COX-2 induction in Aβ-induced neuroinflammation L Dargahi, S Nasiraei-Moghadam, A Abdi, L Khalaj, F Moradi, ... Journal of Molecular Neuroscience 45, 10-21, 2011 | 44 | 2011 |
Apoptosis inhibition can be threatening in Aβ-induced neuroinflammation, through promoting cell proliferation A Abdi, H Sadraie, L Dargahi, L Khalaj, A Ahmadiani Neurochemical Research 36, 39-48, 2011 | 41 | 2011 |
Gemfibrozil pretreatment proved protection against acute restraint stress-induced changes in the male rats' hippocampus L Khalaj, SC Nejad, M Mohammadi, SS Zadeh, MH Pour, A Ahmadiani, ... Brain research 1527, 117-130, 2013 | 31 | 2013 |
Targeting adenosine monophosphate‐activated protein kinase by metformin adjusts post‐ischemic hyperemia and extracellular neuronal discharge in transient global cerebral ischemia Y Farbood, A Sarkaki, L Khalaj, F Khodagholi, M Badavi, G Ashabi Microcirculation 22 (7), 534-541, 2015 | 27 | 2015 |
Gemfibrozil pretreatment resulted in a sexually dimorphic outcome in the Rat models of global cerebral ischemia–reperfusion via modulation of mitochondrial Pro-survival and … F Mohagheghi, A Ahmadiani, B Rahmani, F Moradi, N Romond, L Khalaj Journal of Molecular Neuroscience 50, 379-393, 2013 | 24 | 2013 |
Subchronic metformin pretreatment enhances novel object recognition memory task in forebrain ischemia: behavioural, molecular, and electrophysiological studies G Ashabi, A Sarkaki, F Khodagholi, S Zareh Shahamati, M Goudarzvand, ... Canadian journal of physiology and pharmacology 95 (4), 388-395, 2017 | 22 | 2017 |
Acute 17β-estradiol pretreatment protects against abdominal aortic occlusion induced spinal cord ischemic-reperfusion injury L Khalaj, H Peirovi, F Khodagholi, A Abdi, L Dargahi, A Ahmadiani Neurochemical research 36, 268-280, 2011 | 16 | 2011 |
Assessing competence of broccoli consumption on inflammatory and antioxidant pathways in restraint‐induced models: estimation in rat hippocampus and prefrontal cortex L Khalaj, S Chavoshi Nejad, M Mohammadi, S Sarraf Zadeh, ... BioMed research international 2013 (1), 590379, 2013 | 11 | 2013 |
Simultaneous inhibition of COX-2 and activation of PPAR-γ resulted in the same level and pattern of neuroprotection as they were targeted separately SB Abraki, L Khalaj, F Shaerzadeh, F Khodagholi Journal of Molecular Neuroscience 49, 116-129, 2013 | 11 | 2013 |
Antinociceptive effect of [Met5] enkephalin semicarbazide is not affected by dipeptidyl carboxypeptidase‐I Z Rezaee, SA Arabanian, S Balalaie, A Ahmadiani, L Khalaj, S Nasoohi Journal of Peptide Science 18 (2), 92-96, 2012 | 6 | 2012 |
P3‐302: Alginate oligosaccharide protects against H2O2‐induced endoplasmic reticulum‐and mitochondrial‐mediated apoptotic cell death F Khodagholi, G Ashabi, SK Tusi, L Khalaj, M Kiaei Alzheimer's & Dementia 7, S613-S613, 2011 | 4 | 2011 |
Inhibition of PPAR-γ using GW, attenuates transcription factor Nrf-2 expression in PC12 cells SB Abraki, L Khalaj, SK Tusi, SZ Alamdari, F Khodagholi Alzheimer's & Dementia 7 (4), S608-S609, 2011 | 4 | 2011 |
Caspase inhibition in neuroinflammation induced by soluble β amyloid monomer, protects cells from abnormal survival and proliferation, via attenuation of NFκB activity A Abdi, F Mohagheghi, SH Sadraie, L Dargahi, L Khalaj, A Ahmadiani Physiology and Pharmacology 14 (3), 211-219, 2010 | 2 | 2010 |
Gemfibrozil protect PC12 cells through modulation of Estradiol receptors against oxidative stress G Ashabi, L Khalaj Physiology and Pharmacology 19 (4), 253-262, 2016 | | 2016 |