Preclinical and clinical demonstration of immunogenicity by mRNA vaccines against H10N8 and H7N9 influenza viruses K Bahl, JJ Senn, O Yuzhakov, A Bulychev, LA Brito, KJ Hassett, ME Laska, ... Molecular Therapy 25 (6), 1316-1327, 2017 | 662 | 2017 |
Optimization of lipid nanoparticles for intramuscular administration of mRNA vaccines KJ Hassett, KE Benenato, E Jacquinet, A Lee, A Woods, O Yuzhakov, ... Molecular Therapy-Nucleic Acids 15, 1-11, 2019 | 616 | 2019 |
Efficient targeting and activation of antigen-presenting cells in vivo after modified mRNA vaccine administration in rhesus macaques F Liang, G Lindgren, A Lin, EA Thompson, S Ols, J Röhss, S John, ... Molecular Therapy 25 (12), 2635-2647, 2017 | 314 | 2017 |
Multi-antigenic human cytomegalovirus mRNA vaccines that elicit potent humoral and cell-mediated immunity S John, O Yuzhakov, A Woods, J Deterling, K Hassett, CA Shaw, ... Vaccine 36 (12), 1689-1699, 2018 | 219 | 2018 |
Impact of lipid nanoparticle size on mRNA vaccine immunogenicity KJ Hassett, J Higgins, A Woods, B Levy, Y Xia, CJ Hsiao, E Acosta, ... Journal of Controlled Release 335, 237-246, 2021 | 204 | 2021 |
Overview of vaccine adjuvants: introduction, history, and current status RR Shah, KJ Hassett, LA Brito Vaccine adjuvants: methods and protocols, 1-13, 2017 | 139 | 2017 |
Induction of robust B cell responses after influenza mRNA vaccination is accompanied by circulating hemagglutinin-specific ICOS+ PD-1+ CXCR3+ T follicular helper cells G Lindgren, S Ols, F Liang, EA Thompson, A Lin, F Hellgren, K Bahl, ... Frontiers in immunology 8, 1539, 2017 | 136 | 2017 |
Stabilization of a recombinant ricin toxin A subunit vaccine through lyophilization KJ Hassett, MC Cousins, LA Rabia, CM Chadwick, JM O’Hara, P Nandi, ... European Journal of Pharmaceutics and Biopharmaceutics 85 (2), 279-286, 2013 | 61 | 2013 |
Development of a highly thermostable, adjuvanted human papillomavirus vaccine KJ Hassett, NM Meinerz, F Semmelmann, MC Cousins, RL Garcea, ... European Journal of Pharmaceutics and Biopharmaceutics 94, 220-228, 2015 | 51 | 2015 |
Rhesus macaque myeloid-derived suppressor cells demonstrate T cell inhibitory functions and are transiently increased after vaccination A Lin, F Liang, EA Thompson, M Vono, S Ols, G Lindgren, K Hassett, ... The Journal of Immunology 200 (1), 286-294, 2018 | 41 | 2018 |
Glassy-state stabilization of a dominant negative inhibitor anthrax vaccine containing aluminum hydroxide and glycopyranoside lipid A adjuvants KJ Hassett, DJ Vance, NK Jain, N Sahni, LA Rabia, MC Cousins, S Joshi, ... Journal of pharmaceutical sciences 104 (2), 627-639, 2015 | 35 | 2015 |
Yuzhakov 0, Himansu S, Deterling J, Geilich BM, Ketova T, Mihai C, Lynn A, McFadyen I, et al.,“Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA … KJ Hassett, KE Benenato, E Jacquinet, A Lee, A Woods Mol Ther Nucleic Acids 15, 1-11, 2019 | 23 | 2019 |
Human cytomegalovirus vaccine JF Kramarczyk, K Hassett, S John, P White, A Carfi US Patent 11,406,703, 2022 | 17 | 2022 |
Thermostable Vaccine Compositions and Methods of Preparing Same K Hassett, P Nandi, R Brey, J Carpenter, TW Randolph US Patent App. 13/474,661, 2013 | 16 | 2013 |
Methods of making lipid nanoparticles J Schariter, K Hassett, M Smith, O Almarsson, L Brito US Patent 11,744,801, 2023 | 15 | 2023 |
mRNA vaccine trafficking and resulting protein expression after intramuscular administration KJ Hassett, IL Rajlic, K Bahl, R White, K Cowens, E Jacquinet, KE Burke Molecular Therapy-Nucleic Acids 35 (1), 2024 | 8 | 2024 |
Rational design and in vivo characterization of mRNA-encoded broadly neutralizing antibody combinations against HIV-1 E Narayanan, S Falcone, SM Elbashir, H Attarwala, K Hassett, ... Antibodies 11 (4), 67, 2022 | 7 | 2022 |
Thermostable Vaccine Compositions and Methods of Preparing Same K Hassett, P Nandi, RN Brey, J Carpenter, T Randolph US Patent App. 15/694,023, 2018 | 5 | 2018 |
Corrigendum: induction of robust B cell responses after influenza mrna vaccination is accompanied by circulating hemagglutinin-specific ICOS+ PD-1+ CXCR3+ T follicular helper cells G Lindgren, S Ols, F Liang, EA Thompson, A Lin, F Hellgren, K Bahl, ... Frontiers in immunology 10, 614, 2019 | 2 | 2019 |
Compositions, methods and uses for thermally stable human papillomavirus formulations T Randolph, R Garcea, KJ Hassett US Patent App. 15/309,169, 2017 | 2 | 2017 |