Thiol-to-amine cyclization reaction enables screening of large libraries of macrocyclic compounds and the generation of sub-kilodalton ligands SS Kale, M Bergeron-Brlek, Y Wu, MG Kumar, MV Pham, J Bortoli, J Vesin, ... Science advances 5 (8), eaaw2851, 2019 | 41 | 2019 |
Emerging molecular receptors for the specific-target delivery of ruthenium and gold complexes into cancer cells JF Machado, JDG Correia, TS Morais Molecules 26 (11), 3153, 2021 | 23 | 2021 |
Novel “ruthenium cyclopentadienyl”–peptide conjugate complexes against human FGFR (+) breast cancer JF Machado, M Machuqueiro, F Marques, MP Robalo, MFM Piedade, ... Dalton Transactions 49 (18), 5974-5987, 2020 | 20 | 2020 |
gold (I) bis (1, 2, 3-triazol-5-ylidene) complexes as promising selective anticancer compounds JF Schlagintweit, CHG Jakob, NL Wilke, M Ahrweiler, C Frias, J Frias, ... Journal of Medicinal Chemistry 64 (21), 15747-15757, 2021 | 19 | 2021 |
Comprehensive Organic Chemistry Experiments for the Laboratory Classroom CAM Afonso, NR Candeias, DP Simão, AF Trindade, JAS Coelho, B Tan, ... Royal Society of Chemistry, 2016 | 18* | 2016 |
Less exploited GPCRs in precision medicine: targets for molecular imaging and theranostics J Franco Machado, RD Silva, R Melo, JD G. Correia Molecules 24 (1), 49, 2018 | 16 | 2018 |
Copper (I)‐Thiosemicarbazone Complexes with Dual Anticancer and Antiparasitic Activity JF Machado, F Marques, T Pinheiro, MJ Villa de Brito, G Scalese, ... ChemMedChem 18 (14), e202300074, 2023 | 13 | 2023 |
New copper (i) complexes selective for prostate cancer cells JF Machado, D Sequeira, F Marques, MFM Piedade, MJV de Brito, ... Dalton Transactions 49 (35), 12273-12286, 2020 | 13 | 2020 |
Are smart delivery systems the solution to overcome the lack of selectivity of current metallodrugs in cancer therapy? JF Machado, TS Morais Dalton Transactions 51 (7), 2593-2609, 2022 | 10 | 2022 |
Ultrasonication Improves Solid Phase Synthesis of Peptides Specific for Fibroblast Growth Factor Receptor and for the Protein-Protein Interface RANK-TRAF6 RDM Silva, J Franco Machado, K Gonçalves, FM Lucas, S Batista, R Melo, ... Molecules 26 (23), 7349, 2021 | 6 | 2021 |
[15]aneN4S: Synthesis, Thermodynamic Studies and Potential Applications in Chelation Therapy N Torres, S Gonçalves, AS Fernandes, J Franco Machado, ... Molecules 19 (1), 550-567, 2014 | 6 | 2014 |
Exploiting Co (III)-Cyclopentadienyl Complexes To Develop Anticancer Agents J Franco Machado, S Cordeiro, JN Duarte, PJ Costa, PJ Mendes, ... Inorganic Chemistry 63 (13), 5783-5804, 2024 | 3 | 2024 |
Dual FGFR-targeting and pH-activatable ruthenium–peptide conjugates for targeted therapy of breast cancer JF Machado, M Sá, I Pires, MT da Silva, F Marques, JAS Coelho, ... Dalton Transactions 53 (18), 7682-7693, 2024 | | 2024 |
Organometallic complex, controlled-release multi-functional drug, pharmaceutical composition, processes for the preparation thereof and their use TS Morais, MH Garcia, J Franco Machado WO Patent WO2023199134A1, 2023 | | 2023 |