| Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling HM Abdul, MA Sama, JL Furman, DM Mathis, TL Beckett, AM Weidner, ... Journal of Neuroscience 29 (41), 12957-12969, 2009 | 339 | 2009 |
| Targeting astrocytes ameliorates neurologic changes in a mouse model of Alzheimer's disease JL Furman, DM Sama, JC Gant, TL Beckett, MP Murphy, AD Bachstetter, ... Journal of Neuroscience 32 (46), 16129-16140, 2012 | 330 | 2012 |
| Long-term pioglitazone treatment improves learning and attenuates pathological markers in a mouse model of Alzheimer's disease JL Searcy, JT Phelps, T Pancani, I Kadish, J Popovic, KL Anderson, ... Journal of Alzheimer's Disease 30 (4), 943-961, 2012 | 175 | 2012 |
| BACE1 and BACE2 enzymatic activities in Alzheimer’s disease RR Ahmed, CJ Holler, RL Webb, F Li, TL Beckett, MP Murphy Journal of neurochemistry 112 (4), 1045-1053, 2010 | 158 | 2010 |
| Oxidative modification of lipoic acid by HNE in Alzheimer disease brain SS Hardas, R Sultana, AM Clark, TL Beckett, LI Szweda, MP Murphy, ... Redox biology 1 (1), 80-85, 2013 | 140 | 2013 |
| Association between frontal cortex oxidative damage and beta-amyloid as a function of age in Down syndrome G Cenini, ALS Dowling, TL Beckett, E Barone, C Mancuso, MP Murphy, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1822 (2), 130-138, 2012 | 140 | 2012 |
| Bridging integrator 1 (BIN1) protein expression increases in the Alzheimer's disease brain and correlates with neurofibrillary tangle pathology CJ Holler, PR Davis, TL Beckett, TL Platt, RL Webb, E Head, MP Murphy Journal of Alzheimer's Disease 42 (4), 1221-1227, 2014 | 126 | 2014 |
| Effects of aging and genotype on circadian rhythms, sleep, and clock gene expression in APPxPS1 knock-in mice, a model for Alzheimer's disease MJ Duncan, JT Smith, KM Franklin, TL Beckett, MP Murphy, DKS Clair, ... Experimental neurology 236 (2), 249-258, 2012 | 115 | 2012 |
| Nucleic acid oxidation: an early feature of Alzheimer's disease MA Bradley‐Whitman, MD Timmons, TL Beckett, MP Murphy, BC Lynn, ... Journal of neurochemistry 128 (2), 294-304, 2014 | 114 | 2014 |
| Down syndrome individuals with Alzheimer's disease have a distinct neuroinflammatory phenotype compared to sporadic Alzheimer's disease DM Wilcock, J Hurban, AM Helman, TL Sudduth, KL McCarty, TL Beckett, ... Neurobiology of aging 36 (9), 2468-2474, 2015 | 102 | 2015 |
| Induction of ketosis may improve mitochondrial function and decrease steady-state amyloid-β precursor protein (APP) levels in the aged dog CM Studzinski, WA MacKay, TL Beckett, ST Henderson, MP Murphy, ... Brain research 1226, 209-217, 2008 | 100 | 2008 |
| A ketogenic diet improves motor performance but does not affect β-amyloid levels in a mouse model of Alzheimer's disease TL Beckett, CM Studzinski, JN Keller, MP Murphy, DM Niedowicz Brain research 1505, 61-67, 2013 | 99 | 2013 |
| Preclinical Alzheimer disease: brain oxidative stress, Aβ peptide and proteomics CD Aluise, RAS Robinson, TL Beckett, MP Murphy, J Cai, WM Pierce, ... Neurobiology of disease 39 (2), 221-228, 2010 | 98 | 2010 |
| Calcineurin/NFAT signaling in activated astrocytes drives network hyperexcitability in Aβ-bearing mice P Sompol, JL Furman, MM Pleiss, SD Kraner, IA Artiushin, SR Batten, ... Journal of Neuroscience 37 (25), 6132-6148, 2017 | 97 | 2017 |
| Aβ solubility and deposition during AD progression and in APP× PS-1 knock-in mice MP Murphy, TL Beckett, Q Ding, E Patel, WR Markesbery, DK St Clair, ... Neurobiology of disease 27 (3), 301-311, 2007 | 96 | 2007 |
| Cognitive impairment in humanized APP× PS1 mice is linked to Aβ1–42 and NOX activation AJ Bruce-Keller, S Gupta, AG Knight, TL Beckett, JM McMullen, PR Davis, ... Neurobiology of disease 44 (3), 317-326, 2011 | 95 | 2011 |
| Amyloid-β peptide and oligomers in the brain and cerebrospinal fluid of aged canines E Head, V Pop, F Sarsoza, R Kayed, TL Beckett, CM Studzinski, JL Tomic, ... Journal of Alzheimer's Disease 20 (2), 637-646, 2010 | 93 | 2010 |
| Obesity, diabetes, and leptin resistance promote tau pathology in a mouse model of disease TL Platt, TL Beckett, K Kohler, DM Niedowicz, MP Murphy Neuroscience 315, 162-174, 2016 | 90 | 2016 |
| Expression of neprilysin in skeletal muscle reduces amyloid burden in a transgenic mouse model of Alzheimer disease Y Liu, C Studzinski, T Beckett, H Guan, MA Hersh, MP Murphy, R Klein, ... Molecular Therapy 17 (8), 1381-1386, 2009 | 88 | 2009 |
| Obesity and diabetes cause cognitive dysfunction in the absence of accelerated β-amyloid deposition in a novel murine model of mixed or vascular dementia DM Niedowicz, VL Reeves, TL Platt, K Kohler, TL Beckett, DK Powell, ... Acta neuropathologica communications 2 (1), 1-17, 2014 | 86 | 2014 |
