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ChangHui Pak
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年份
Rapid single-step induction of functional neurons from human pluripotent stem cells
Y Zhang, CH Pak, Y Han, H Ahlenius, Z Zhang, S Chanda, S Marro, ...
Neuron 78 (5), 785-798, 2013
15242013
Single nucleotide polymorphism associated with mature miR-125a alters the processing of pri-miRNA
R Duan, CH Pak, P Jin
Human molecular genetics 16 (9), 1124-1131, 2007
6162007
Generation of induced neuronal cells by the single reprogramming factor ASCL1
S Chanda, CE Ang, J Davila, CH Pak, M Mall, QY Lee, H Ahlenius, ...
Stem cell reports 3 (2), 282-296, 2014
4002014
Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons
F Yi, T Danko, SC Botelho, C Patzke, CH Pak, M Wernig, TC Südhof
Science 352 (6286), aaf2669, 2016
3202016
Human neuropsychiatric disease modeling using conditional deletion reveals synaptic transmission defects caused by heterozygous mutations in NRXN1
CH Pak, T Danko, Y Zhang, J Aoto, G Anderson, S Maxeiner, F Yi, ...
Cell stem cell 17 (3), 316-328, 2015
2232015
Presynaptic neuronal pentraxin receptor organizes excitatory and inhibitory synapses
SJ Lee, M Wei, C Zhang, S Maxeiner, CH Pak, SC Botelho, J Trotter, ...
Journal of Neuroscience 37 (5), 1062-1080, 2017
1332017
The loss of methyl-CpG binding protein 1 leads to autism-like behavioral deficits
AM Allan, X Liang, Y Luo, CH Pak, X Li, KE Szulwach, D Chen, P Jin, ...
Human molecular genetics 17 (13), 2047-2057, 2008
1122008
Mutation of the conserved polyadenosine RNA binding protein, ZC3H14/dNab2, impairs neural function in Drosophila and humans
CH Pak, M Garshasbi, K Kahrizi, C Gross, LH Apponi, JJ Noto, SM Kelly, ...
Proceedings of the National Academy of Sciences 108 (30), 12390-12395, 2011
982011
A conserved role for the zinc finger polyadenosine RNA binding protein, ZC3H14, in control of poly (A) tail length
SM Kelly, SW Leung, CH Pak, A Banerjee, KH Moberg, AH Corbett
Rna 20 (5), 681-688, 2014
712014
Control of astrocyte quiescence and activation in a synthetic brain hydrogel
S Galarza, AJ Crosby, CH Pak, SR Peyton
Advanced healthcare materials 9 (4), 1901419, 2020
612020
Cross-platform validation of neurotransmitter release impairments in schizophrenia patient-derived NRXN1-mutant neurons
CH Pak, T Danko, VR Mirabella, J Wang, Y Liu, M Vangipuram, S Grieder, ...
Proceedings of the National Academy of Sciences 118 (22), e2025598118, 2021
602021
Epigenetics and neural developmental disorders
X Zhao, CH Pak, RD Smrt, P Jin
Epigenetics 2 (2), 126-134, 2007
592007
The conserved, disease-associated RNA binding protein dNab2 interacts with the fragile X protein ortholog in Drosophila neurons
RS Bienkowski, A Banerjee, JC Rounds, J Rha, OF Omotade, C Gross, ...
Cell reports 20 (6), 1372-1384, 2017
372017
New kid on the ID block: Neural functions of the Nab2/ZC3H14 class of Cys3His tandem zinc-finger polyadenosine RNA binding proteins
SM Kelly, CH Pak, M Garshasbi, A Kuss, AH Corbett, KH Moberg
RNA biology 9 (5), 555-562, 2012
242012
Analyses of the autism-associated neuroligin-3 R451C mutation in human neurons reveal a gain-of-function synaptic mechanism
L Wang, VR Mirabella, R Dai, X Su, R Xu, A Jadali, M Bernabucci, I Singh, ...
Molecular psychiatry, 1-16, 2022
182022
Copy number variants in neurexin genes: phenotypes and mechanisms
MV Fuccillo, CH Pak
Current opinion in genetics & development 68, 64-70, 2021
152021
Schizophrenia-associated NRXN1 deletions induce developmental-timing- and cell-type-specific vulnerabilities in human brain organoids
R Sebastian, K Jin, N Pavon, R Bansal, A Potter, Y Song, J Babu, ...
Nature Communications 14 (1), 3770, 2023
122023
Rapid generation of functional and homogeneous excitatory human forebrain neurons using Neurogenin-2 (Ngn2)
CH Pak, T Sudhof, S Grieder, N Yang, Y Zhang, M Wernig
122018
Probing the molecular and cellular pathological mechanisms of schizophrenia using human induced pluripotent stem cell models
R Sebastian, Y Song, CH Pak
Schizophrenia research, 2022
82022
CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons
D McSweeney, R Gabriel, K Jin, ZP Pang, B Aronow, CH Pak
Iscience 25 (10), 2022
62022
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