Rapid single-step induction of functional neurons from human pluripotent stem cells Y Zhang, CH Pak, Y Han, H Ahlenius, Z Zhang, S Chanda, S Marro, ... Neuron 78 (5), 785-798, 2013 | 1524 | 2013 |
Single nucleotide polymorphism associated with mature miR-125a alters the processing of pri-miRNA R Duan, CH Pak, P Jin Human molecular genetics 16 (9), 1124-1131, 2007 | 616 | 2007 |
Generation of induced neuronal cells by the single reprogramming factor ASCL1 S Chanda, CE Ang, J Davila, CH Pak, M Mall, QY Lee, H Ahlenius, ... Stem cell reports 3 (2), 282-296, 2014 | 400 | 2014 |
Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons F Yi, T Danko, SC Botelho, C Patzke, CH Pak, M Wernig, TC Südhof Science 352 (6286), aaf2669, 2016 | 320 | 2016 |
Human neuropsychiatric disease modeling using conditional deletion reveals synaptic transmission defects caused by heterozygous mutations in NRXN1 CH Pak, T Danko, Y Zhang, J Aoto, G Anderson, S Maxeiner, F Yi, ... Cell stem cell 17 (3), 316-328, 2015 | 223 | 2015 |
Presynaptic neuronal pentraxin receptor organizes excitatory and inhibitory synapses SJ Lee, M Wei, C Zhang, S Maxeiner, CH Pak, SC Botelho, J Trotter, ... Journal of Neuroscience 37 (5), 1062-1080, 2017 | 133 | 2017 |
The loss of methyl-CpG binding protein 1 leads to autism-like behavioral deficits AM Allan, X Liang, Y Luo, CH Pak, X Li, KE Szulwach, D Chen, P Jin, ... Human molecular genetics 17 (13), 2047-2057, 2008 | 112 | 2008 |
Mutation of the conserved polyadenosine RNA binding protein, ZC3H14/dNab2, impairs neural function in Drosophila and humans CH Pak, M Garshasbi, K Kahrizi, C Gross, LH Apponi, JJ Noto, SM Kelly, ... Proceedings of the National Academy of Sciences 108 (30), 12390-12395, 2011 | 98 | 2011 |
A conserved role for the zinc finger polyadenosine RNA binding protein, ZC3H14, in control of poly (A) tail length SM Kelly, SW Leung, CH Pak, A Banerjee, KH Moberg, AH Corbett Rna 20 (5), 681-688, 2014 | 71 | 2014 |
Control of astrocyte quiescence and activation in a synthetic brain hydrogel S Galarza, AJ Crosby, CH Pak, SR Peyton Advanced healthcare materials 9 (4), 1901419, 2020 | 61 | 2020 |
Cross-platform validation of neurotransmitter release impairments in schizophrenia patient-derived NRXN1-mutant neurons CH Pak, T Danko, VR Mirabella, J Wang, Y Liu, M Vangipuram, S Grieder, ... Proceedings of the National Academy of Sciences 118 (22), e2025598118, 2021 | 60 | 2021 |
Epigenetics and neural developmental disorders X Zhao, CH Pak, RD Smrt, P Jin Epigenetics 2 (2), 126-134, 2007 | 59 | 2007 |
The conserved, disease-associated RNA binding protein dNab2 interacts with the fragile X protein ortholog in Drosophila neurons RS Bienkowski, A Banerjee, JC Rounds, J Rha, OF Omotade, C Gross, ... Cell reports 20 (6), 1372-1384, 2017 | 37 | 2017 |
New kid on the ID block: Neural functions of the Nab2/ZC3H14 class of Cys3His tandem zinc-finger polyadenosine RNA binding proteins SM Kelly, CH Pak, M Garshasbi, A Kuss, AH Corbett, KH Moberg RNA biology 9 (5), 555-562, 2012 | 24 | 2012 |
Analyses of the autism-associated neuroligin-3 R451C mutation in human neurons reveal a gain-of-function synaptic mechanism L Wang, VR Mirabella, R Dai, X Su, R Xu, A Jadali, M Bernabucci, I Singh, ... Molecular psychiatry, 1-16, 2022 | 18 | 2022 |
Copy number variants in neurexin genes: phenotypes and mechanisms MV Fuccillo, CH Pak Current opinion in genetics & development 68, 64-70, 2021 | 15 | 2021 |
Schizophrenia-associated NRXN1 deletions induce developmental-timing- and cell-type-specific vulnerabilities in human brain organoids R Sebastian, K Jin, N Pavon, R Bansal, A Potter, Y Song, J Babu, ... Nature Communications 14 (1), 3770, 2023 | 12 | 2023 |
Rapid generation of functional and homogeneous excitatory human forebrain neurons using Neurogenin-2 (Ngn2) CH Pak, T Sudhof, S Grieder, N Yang, Y Zhang, M Wernig | 12 | 2018 |
Probing the molecular and cellular pathological mechanisms of schizophrenia using human induced pluripotent stem cell models R Sebastian, Y Song, CH Pak Schizophrenia research, 2022 | 8 | 2022 |
CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons D McSweeney, R Gabriel, K Jin, ZP Pang, B Aronow, CH Pak Iscience 25 (10), 2022 | 6 | 2022 |