| Epigenetic silencing of the p16INK4a tumor suppressor is associated with loss of CTCF binding and a chromatin boundary M Witcher, BM Emerson Molecular cell 34 (3), 271-284, 2009 | 283 | 2009 |
| Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock L DiTacchio, HD Le, C Vollmers, M Hatori, M Witcher, J Secombe, ... Science 333 (6051), 1881-1885, 2011 | 280 | 2011 |
| Achieving clinical success with BET inhibitors as anti-cancer agents T Shorstova, WD Foulkes, M Witcher British journal of cancer 124 (9), 1478-1490, 2021 | 279 | 2021 |
| Methionine metabolism shapes T helper cell responses through regulation of epigenetic reprogramming DG Roy, J Chen, V Mamane, EH Ma, BM Muhire, RD Sheldon, ... Cell metabolism 31 (2), 250-266. e9, 2020 | 248 | 2020 |
| Epigenetic silencing of tumor suppressor genes: Paradigms, puzzles, and potential A Kazanets, T Shorstova, K Hilmi, M Marques, M Witcher Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1865 (2), 275-288, 2016 | 226 | 2016 |
| Anticancer Properties of Phyllanthus emblica (Indian Gooseberry) T Zhao, Q Sun, M Marques, M Witcher Oxidative medicine and cellular longevity 2015 (1), 950890, 2015 | 153 | 2015 |
| Small-Cell Carcinoma of the Ovary, Hypercalcemic Type-Genetics, New Treatment Targets, and Current Management Guidelines Clinical Cancer Research 26 (25), 3908-3917, 2020 | 126 | 2020 |
| CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary Y Xue, B Meehan, E Macdonald, S Venneti, XQD Wang, L Witkowski, ... Nature communications 10 (1), 558, 2019 | 126 | 2019 |
| Synergy between all-trans retinoic acid and tumor necrosis factor pathways in acute leukemia cells M Witcher, DT Ross, C Rousseau, L Deluca, WH Miller Jr Blood 102 (1), 237-245, 2003 | 90 | 2003 |
| Peroxisomes and cancer: The role of a metabolic specialist in a disease of aberrant metabolism MS Dahabieh, E Di Pietro, M Jangal, C Goncalves, M Witcher, ... Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1870 (1), 103-121, 2018 | 89 | 2018 |
| Genome-wide targeting of the epigenetic regulatory protein CTCF to gene promoters by the transcription factor TFII-I R Peña-Hernández, M Marques, K Hilmi, T Zhao, A Saad, ... Proceedings of the National Academy of Sciences 112 (7), E677-E686, 2015 | 89 | 2015 |
| CTCF facilitates DNA double-strand break repair by enhancing homologous recombination repair K Hilmi, M Jangal, M Marques, T Zhao, A Saad, C Zhang, VM Luo, ... Science advances 3 (5), e1601898, 2017 | 84 | 2017 |
| SWI/SNF-compromised cancers are susceptible to bromodomain inhibitors T Shorstova, M Marques, J Su, J Johnston, CL Kleinman, N Hamel, ... Cancer research 79 (10), 2761-2774, 2019 | 70 | 2019 |
| Competition between translation initiation factor eIF5 and its mimic protein 5MP determines non-AUG initiation rate genome-wide L Tang, J Morris, J Wan, C Moore, Y Fujita, S Gillaspie, E Aube, J Nanda, ... Nucleic acids research 45 (20), 11941-11953, 2017 | 67 | 2017 |
| Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles N Tawil, R Bassawon, B Meehan, A Nehme, L Montermini, T Gayden, ... Blood advances 5 (6), 1682-1694, 2021 | 64 | 2021 |
| Antitumor activity of the dual BET and CBP/EP300 inhibitor NEO2734 F Spriano, E Gaudio, L Cascione, C Tarantelli, F Melle, G Motta, V Priebe, ... Blood advances 4 (17), 4124-4135, 2020 | 62 | 2020 |
| Haploinsufficiency of the ESCRT component HD-PTP predisposes to cancer S Manteghi, MC Gingras, D Kharitidi, L Galarneau, M Marques, M Yan, ... Cell reports 15 (9), 1893-1900, 2016 | 52 | 2016 |
| STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer SP Totten, YK Im, E Cepeda Cañedo, O Najyb, A Nguyen, S Hébert, ... Nature Communications 12 (1), 3299, 2021 | 48 | 2021 |
| BAG-1 p50 isoform interacts with the vitamin D receptor and its cellular overexpression inhibits the vitamin D pathway M Witcher, X Yang, A Pater, SC Tang Experimental Cell Research 265 (1), 167-173, 2001 | 45 | 2001 |
| Combination of retinoic acid and tumor necrosis factor overcomes the maturation block in a variety of retinoic acid-resistant acute promyelocytic leukemia cells M Witcher, HY Shiu, Q Guo, WH Miller Jr Blood 104 (10), 3335-3342, 2004 | 44 | 2004 |
