A review of pharmaceutical extrusion: Critical process parameters and scaling-up J Thiry, F Krier, B Evrard International journal of pharmaceutics 479 (1), 227-240, 2015 | 174 | 2015 |
Continuous production of itraconazole-based solid dispersions by hot melt extrusion: Preformulation, optimization and design space determination J Thiry, P Lebrun, C Vinassa, M Adam, L Netchacovitch, E Ziemons, ... International journal of pharmaceutics 515 (1-2), 114-124, 2016 | 80 | 2016 |
Bioavailability enhancement of itraconazole-based solid dispersions produced by hot melt extrusion in the framework of the Three Rs rule J Thiry, MGM Kok, L Collard, A Frère, F Krier, M Fillet, B Evrard European Journal of Pharmaceutical Sciences 99, 1-8, 2017 | 59 | 2017 |
Investigation of a suitable in vitro dissolution test for itraconazole-based solid dispersions J Thiry, G Broze, A Pestieau, AS Tatton, F Baumans, C Damblon, F Krier, ... European Journal of Pharmaceutical Sciences 85, 94-105, 2016 | 57 | 2016 |
Hot-melt extrusion as a continuous manufacturing process to form ternary cyclodextrin inclusion complexes J Thiry, F Krier, S Ratwatte, JM Thomassin, C Jerome, B Evrard European Journal of Pharmaceutical Sciences 96, 590-597, 2017 | 50 | 2017 |
PAT tools for the control of co-extrusion implants manufacturing process F Krier, J Mantanus, PY Sacré, PF Chavez, J Thiry, A Pestieau, E Rozet, ... International journal of pharmaceutics 458 (1), 15-24, 2013 | 46 | 2013 |
Development of an analytical method for crystalline content determination in amorphous solid dispersions produced by hot-melt extrusion using transmission Raman spectroscopy: a … L Netchacovitch, E Dumont, J Cailletaud, J Thiry, C De Bleye, PY Sacré, ... International journal of pharmaceutics 530 (1-2), 249-255, 2017 | 31 | 2017 |
Sampling only ten microliters of whole blood for the quantification of poorly soluble drugs: itraconazole as case study J Thiry, B Evrard, G Nys, M Fillet, MGM Kok Journal of Chromatography a 1479, 161-168, 2017 | 31 | 2017 |
Vibrational spectroscopy and microspectroscopy analyzing qualitatively and quantitatively pharmaceutical hot melt extrudates L Netchacovitch, J Thiry, C De Bleye, PF Chavez, F Krier, PY Sacré, ... Journal of Pharmaceutical and Biomedical Analysis 113, 21-33, 2015 | 28 | 2015 |
Global approach for the validation of an in-line Raman spectroscopic method to determine the API content in real-time during a hot-melt extrusion process L Netchacovitch, J Thiry, C De Bleye, E Dumont, J Cailletaud, PY Sacré, ... Talanta 171, 45-52, 2017 | 22 | 2017 |
Core cross-linked micelles of polyphosphoester containing amphiphilic block copolymers as drug nanocarriers ZE Yilmaz, S Vanslambrouck, S Cajot, J Thiry, A Debuigne, P Lecomte, ... RSC advances 6 (48), 42081-42088, 2016 | 18 | 2016 |
Modeling, sensitivity analysis and parameter identification of a twin screw extruder J Grimard, L Dewasme, J Thiry, F Krier, B Evrard, AV Wouwer IFAC-PapersOnLine 49 (7), 1127-1132, 2016 | 9 | 2016 |
A simple calibration approach based on film-casting for confocal Raman microscopy to support the development of a hot-melt extrusion process L Netchacovitch, J Thiry, C De Bleye, E Dumont, A Dispas, C Hubert, ... Talanta 154, 392-399, 2016 | 5 | 2016 |
Development of a continuous hot melt extrusion process for manufacturing solid oral dosage forms containing a BCS II drug. J Thiry Université de Liège, 2016 | 3 | 2016 |
Preformulation study of an itraconazole-based oral dosage produced by hot-melt extrusion J Thiry, F Krier, A Pestieau, B Evrard AAPS Annual Meeting San Diego 2014, 2014 | 2 | 2014 |
Preliminary Development of Solid Dispersion for an Insoluble Compound ZL006 by Miniaturized Hot Melt Extrusion L Zhang, H Luan, W Lu, H Wang Pharmaceutical Fronts 1 (01), e11-e21, 2019 | 1 | 2019 |
Device for the continuous production of solid dosage forms, and use of said device for medicinal drugs and/or use thereof for food supplements J Thiry, F Krier, B Evrard, A Nuozzi, C Emmerechts, E Beeckman US Patent App. 16/340,625, 2020 | | 2020 |
Sampling only 10 μL of whole blood to study the bioavailability of itraconazole formulations in rats M Kok, J Thiry, B Evrard, G Nys, M Fillet International Symposium on Electro-and Liquid Phase-Separation Techniques (ITP), 2017 | | 2017 |
Development of an original thermoforming apparatus to be coupled to hot melt extrusion for the continuous production of itraconazole-based amorphous solid dispersions J Thiry, A Nuozzi, C Emmerechts, E Beeckman, F Krier, B Evrard 2nd European Meeting on Pharmaceutics, 2017 | | 2017 |
Blood microsampling for itraconazole pharmacokinetic study on individual rodent in the context of drug formulation optimization M Fillet, J Thiry, B Evrard, G Nys, AC Servais, M Kok Recent Developments in Pharmaceutical Analysis (RDA 2017), 2017 | | 2017 |