| Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV TP Sheahan, AC Sims, SR Leist, A Schäfer, J Won, AJ Brown, ... Nature communications 11 (1), 222, 2020 | 2201 | 2020 |
| Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses TP Sheahan, AC Sims, RL Graham, VD Menachery, LE Gralinski, ... Science translational medicine 9 (396), eaal3653, 2017 | 1887 | 2017 |
| Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys TK Warren, R Jordan, MK Lo, AS Ray, RL Mackman, V Soloveva, ... Nature 531 (7594), 381-385, 2016 | 1722 | 2016 |
| Coronavirus susceptibility to the antiviral remdesivir (GS-5734) is mediated by the viral polymerase and the proofreading exoribonuclease ML Agostini, EL Andres, AC Sims, RL Graham, TP Sheahan, X Lu, ... MBio 9 (2), 10.1128/mbio. 00221-18, 2018 | 1417 | 2018 |
| Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection E De Wit, F Feldmann, J Cronin, R Jordan, A Okumura, T Thomas, D Scott, ... Proceedings of the National Academy of Sciences 117 (12), 6771-6776, 2020 | 1108 | 2020 |
| Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and … D Siegel, HC Hui, E Doerffler, MO Clarke, K Chun, L Zhang, S Neville, ... Journal of medicinal chemistry 60 (5), 1648-1661, 2017 | 780 | 2017 |
| Molecular viral oncology of hepatocellular carcinoma TM Block, AS Mehta, CJ Fimmel, R Jordan Oncogene 22 (33), 5093-5107, 2003 | 679 | 2003 |
| GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and Paramyxoviruses MK Lo, R Jordan, A Arvey, J Sudhamsu, P Shrivastava-Ranjan, AL Hotard, ... Scientific reports 7 (1), 43395, 2017 | 551 | 2017 |
| Different conformations for the same polypeptide bound to chaperones DnaK and GroEL SJ Landry, R Jordan, R McMacken, LM Gierasch Nature 355 (6359), 455-457, 1992 | 394 | 1992 |
| Oral GS-5806 activity in a respiratory syncytial virus challenge study JP DeVincenzo, RJ Whitley, RL Mackman, C Scaglioni-Weinlich, ... New England Journal of Medicine 371 (8), 711-722, 2014 | 362 | 2014 |
| Ribonucleoside analogue that blocks replication of bovine viral diarrhea and hepatitis C viruses in culture LJ Stuyver, T Whitaker, TR McBrayer, BI Hernandez-Santiago, S Lostia, ... Antimicrobial agents and chemotherapy 47 (1), 244-254, 2003 | 267 | 2003 |
| Severe eczema vaccinatum in a household contact of a smallpox vaccinee S Vora, I Damon, V Fulginiti, SG Weber, M Kahana, SL Stein, SI Gerber, ... Clinical Infectious Diseases 46 (10), 1555-1561, 2008 | 252 | 2008 |
| Remdesivir (GS-5734) protects African green monkeys from Nipah virus challenge MK Lo, F Feldmann, JM Gary, R Jordan, R Bannister, J Cronin, NR Patel, ... Science translational medicine 11 (494), eaau9242, 2019 | 235 | 2019 |
| Replication of a cytopathic strain of bovine viral diarrhea virus activates PERK and induces endoplasmic reticulum stress-mediated apoptosis of MDBK cells R Jordan, L Wang, TM Graczyk, TM Block, PR Romano Journal of virology 76 (19), 9588-9599, 2002 | 235 | 2002 |
| Nonhuman primates are protected from smallpox virus or monkeypox virus challenges by the antiviral drug ST-246 J Huggins, A Goff, L Hensley, E Mucker, J Shamblin, C Wlazlowski, ... Antimicrobial agents and chemotherapy 53 (6), 2620-2625, 2009 | 190 | 2009 |
| Modulation of the ATPase activity of the molecular chaperone DnaK by peptides and the DnaJ and GrpE heat shock proteins (∗) R Jordan, R McMacken Journal of Biological Chemistry 270 (9), 4563-4569, 1995 | 177 | 1995 |
| A novel inhibitor of dengue virus replication that targets the capsid protein CM Byrd, D Dai, DW Grosenbach, A Berhanu, KF Jones, KB Cardwell, ... Antimicrobial agents and chemotherapy 57 (1), 15-25, 2013 | 161 | 2013 |
| ST-246 antiviral efficacy in a nonhuman primate monkeypox model: determination of the minimal effective dose and human dose justification R Jordan, A Goff, A Frimm, ML Corrado, LE Hensley, CM Byrd, E Mucker, ... Antimicrobial agents and chemotherapy 53 (5), 1817-1822, 2009 | 151 | 2009 |
| Efficacy of delayed treatment with ST-246 given orally against systemic orthopoxvirus infections in mice DC Quenelle, RML Buller, S Parker, KA Keith, DE Hruby, R Jordan, ... Antimicrobial agents and chemotherapy 51 (2), 689-695, 2007 | 149 | 2007 |
| Synergistic efficacy of the combination of ST-246 with CMX001 against orthopoxviruses DC Quenelle, MN Prichard, KA Keith, DE Hruby, R Jordan, GR Painter, ... Antimicrobial agents and chemotherapy 51 (11), 4118-4124, 2007 | 143 | 2007 |
