Zn2+ inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture AJW Te Velthuis, SHE van den Worm, AC Sims, RS Baric, EJ Snijder, ... PLoS pathogens 6 (11), e1001176, 2010 | 1140 | 2010 |
Influenza virus RNA polymerase: insights into the mechanisms of viral RNA synthesis AJW Te Velthuis, E Fodor Nature Reviews Microbiology 14 (8), 479-493, 2016 | 462 | 2016 |
The mechanism of resistance to favipiravir in influenza DH Goldhill, AJW Te Velthuis, RA Fletcher, P Langat, M Zambon, ... Proceedings of the National Academy of Sciences 115 (45), 11613-11618, 2018 | 313 | 2018 |
The SARS-coronavirus nsp7+nsp8 complex is a unique multimeric RNA polymerase capable of both de novo initiation and primer extension AJW Te Velthuis, SHE Van Den Worm, EJ Snijder Nucleic acids research 40 (4), 1737-1747, 2012 | 311 | 2012 |
The RNA polymerase activity of SARS-coronavirus nsp12 is primer dependent AJW Te Velthuis, JJ Arnold, CE Cameron, SHE Van Den Worm, ... Nucleic acids research 38 (1), 203-214, 2010 | 272 | 2010 |
Common and unique features of viral RNA-dependent polymerases AJW Te Velthuis Cellular and molecular life sciences 71, 4403-4420, 2014 | 239 | 2014 |
Mechanism of nucleic acid unwinding by SARS-CoV helicase AO Adedeji, B Marchand, AJW Te Velthuis, EJ Snijder, S Weiss, RL Eoff, ... PloS one 7 (5), e36521, 2012 | 208 | 2012 |
Nidovirus RNA polymerases: complex enzymes handling exceptional RNA genomes CC Posthuma, AJW te Velthuis, EJ Snijder Virus Research, 2017 | 124 | 2017 |
Quantitative guidelines for force calibration through spectral analysis of magnetic tweezers data AJW Te Velthuis, JWJ Kerssemakers, J Lipfert, NH Dekker Biophysical journal 99 (4), 1292-1302, 2010 | 124 | 2010 |
Mini viral RNAs act as innate immune agonists during influenza virus infection AJW Te Velthuis, JC Long, DLV Bauer, RLY Fan, HL Yen, J Sharps, ... Nature microbiology 3 (11), 1234-1242, 2018 | 113 | 2018 |
The role of the priming loop in influenza A virus RNA synthesis AJW Te Velthuis, NC Robb, AN Kapanidis, E Fodor Nature microbiology 1 (5), 1-7, 2016 | 110 | 2016 |
Single-cell virus sequencing of influenza infections that trigger innate immunity AB Russell, E Elshina, JR Kowalsky, AJW Te Velthuis, JD Bloom Journal of virology 93 (14), 10.1128/jvi. 00500-19, 2019 | 109 | 2019 |
Structure and function of the influenza virus transcription and replication machinery E Fodor, AJW Te Velthuis Cold Spring Harbor perspectives in medicine 10 (9), a038398, 2020 | 108 | 2020 |
PDZ and LIM domain‐encoding genes: molecular interactions and their role in development AJW Te Velthuis, CP Bagowski The Scientific World Journal 7 (1), 1470-1492, 2007 | 102 | 2007 |
Structural insights into RNA polymerases of negative-sense RNA viruses AJW Te Velthuis, JM Grimes, E Fodor Nature Reviews Microbiology 19 (5), 303-318, 2021 | 91 | 2021 |
Molecular evolution of the MAGUK family in metazoan genomes AJW Te Velthuis, JF Admiraal, CP Bagowski BMC evolutionary biology 7, 1-10, 2007 | 90 | 2007 |
Insights into the molecular evolution of the PDZ/LIM family and identification of a novel conserved protein motif AJW Te Velthuis, T Isogai, L Gerrits, CP Bagowski PloS one 2 (2), e189, 2007 | 82 | 2007 |
Integrity of the early secretory pathway promotes, but is not required for, severe acute respiratory syndrome coronavirus RNA synthesis and virus-induced remodeling of … K Knoops, C Swett-Tapia, SHE Van Den Worm, AJW Te Velthuis, ... Journal of virology 84 (2), 833-846, 2010 | 72 | 2010 |
Role of the PB2 627 domain in influenza A virus polymerase function BE Nilsson, AJW Te Velthuis, E Fodor Journal of virology 91 (7), 10.1128/jvi. 02467-16, 2017 | 62 | 2017 |
The nature of protein domain evolution: shaping the interaction network C P Bagowski, W Bruins, A JW te Velthuis Current genomics 11 (5), 368-376, 2010 | 54 | 2010 |