DNA methylation as a mediator of HLA-DRB1* 15: 01 and a protective variant in multiple sclerosis L Kular, Y Liu, S Ruhrmann, G Zheleznyakova, F Marabita, ... Nature communications 9 (1), 1-15, 2018 | 190 | 2018 |
Competitive repopulation of an empty microglial niche yields functionally distinct subsets of microglia-like cells H Lund, M Pieber, R Parsa, J Han, D Grommisch, E Ewing, L Kular, ... Nature communications 9 (1), 1-13, 2018 | 186 | 2018 |
Therapeutic efficacy of dimethyl fumarate in relapsing-remitting multiple sclerosis associates with ROS pathway in monocytes KE Carlström, E Ewing, M Granqvist, A Gyllenberg, S Aeinehband, ... Nature communications 10 (1), 1-13, 2019 | 125 | 2019 |
Microglial autophagy–associated phagocytosis is essential for recovery from neuroinflammation R Berglund, AO Guerreiro-Cacais, MZ Adzemovic, M Zeitelhofer, H Lund, ... Science immunology 5 (52), eabb5077, 2020 | 103 | 2020 |
Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-β signaling H Lund, M Pieber, R Parsa, D Grommisch, E Ewing, L Kular, J Han, K Zhu, ... Nature immunology 19 (5), 1-7, 2018 | 67 | 2018 |
Combining evidence from four immune cell types identifies DNA methylation patterns that implicate functionally distinct pathways during Multiple Sclerosis progression E Ewing, L Kular, SJ Fernandes, N Karathanasis, V Lagani, S Ruhrmann, ... EBioMedicine 43, 411-423, 2019 | 58 | 2019 |
Epigenetic research in multiple sclerosis: progress, challenges, and opportunities GY Zheleznyakova, E Piket, F Marabita, M Pahlevan Kakhki, E Ewing, ... Physiological genomics 49 (9), 447-461, 2017 | 53 | 2017 |
Hypermethylation of MIR21 in CD4+ T cells from patients with relapsing-remitting multiple sclerosis associates with lower miRNA-21 levels and concomitant up … S Ruhrmann, E Ewing, E Piket, L Kular, JC Cetrulo Lorenzi, SJ Fernandes, ... Multiple Sclerosis Journal 24 (10), 1288-1300, 2018 | 45 | 2018 |
Gsta4 controls apoptosis of differentiating adult oligodendrocytes during homeostasis and remyelination via the mitochondria-associated Fas-Casp8-Bid-axis KE Carlström, K Zhu, E Ewing, IE Krabbendam, RA Harris, AM Falcão, ... Nature communications 11 (1), 1-13, 2020 | 40 | 2020 |
Epigenetic alterations associated with early prenatal dexamethasone treatment L Karlsson, M Barbaro, E Ewing, D Gomez-Cabrero, S Lajic Journal of the Endocrine Society 3 (1), 250-263, 2019 | 38 | 2019 |
STATegra: multi-omics data integration–a conceptual scheme with a bioinformatics pipeline N Planell, V Lagani, P Sebastian-Leon, F van der Kloet, E Ewing, ... Frontiers in genetics 12, 620453, 2021 | 33 | 2021 |
Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis L Kular, M Needhamsen, MZ Adzemovic, T Kramarova, D Gomez-Cabrero, ... Clinical epigenetics 11 (1), 1-20, 2019 | 30 | 2019 |
Usability of human Infinium MethylationEPIC BeadChip for mouse DNA methylation studies M Needhamsen, E Ewing, H Lund, D Gomez-Cabrero, RA Harris, L Kular, ... BMC bioinformatics 18 (1), 1-9, 2017 | 28 | 2017 |
DNA methylation changes in glial cells of the normal-appearing white matter in Multiple Sclerosis patients L Kular, E Ewing, M Needhamsen, M Pahlevan Kakhki, R Covacu, ... Epigenetics, 1-20, 2022 | 18 | 2022 |
Non-parametric combination analysis of multiple data types enables detection of novel regulatory mechanisms in T cells of multiple sclerosis patients SJ Fernandes, H Morikawa, E Ewing, S Ruhrmann, RN Joshi, V Lagani, ... Scientific reports 9 (1), 1-12, 2019 | 16 | 2019 |
Epigenetic clock indicates accelerated ageing in glial cells of progressive Multiple Sclerosis patients L Kular, D Klose, A Urdánoz-Casado, E Ewing, N Planell, ... Frontiers in Aging Neuroscience, 880, 0 | 14 | |
GeneSetCluster: a tool for summarizing and integrating gene-set analysis results E Ewing, N Planell-Picola, M Jagodic, D Gomez-Cabrero BMC bioinformatics 21 (1), 1-7, 2020 | 12 | 2020 |
Transcriptomic Profiling Reveals That HMGB1 Induces Macrophage Polarization Different from Classical M1 H Qu, R Heinbäck, H Salo, E Ewing, A Espinosa, C Aulin, ... Biomolecules 12 (6), 779, 2022 | 6 | 2022 |
DNA methylation as a mediator of HLA-DRB1415: 01 and a protective variant in multiple sclerosis. Nat Commun. 2018; 9 (1): 2397 L Kular, Y Liu, S Ruhrmann, G Zheleznyakova, F Marabita, ... | 5 | |
Neurofilament light chain as a marker for cortical atrophy in multiple sclerosis without radiological signs of disease activity BV Ineichen, T Moridi, E Ewing, R Ouellette, A Manouchehrinia, ... Journal of internal medicine 290 (2), 473-476, 2021 | 4 | 2021 |