RBP4 activates antigen-presenting cells, leading to adipose tissue inflammation and systemic insulin resistance PM Moraes-Vieira, MM Yore, PM Dwyer, I Syed, P Aryal, BB Kahn Cell metabolism 19 (3), 512-526, 2014 | 285 | 2014 |
Retinol-binding protein 4 inhibits insulin signaling in adipocytes by inducing proinflammatory cytokines in macrophages through a c-Jun N-terminal kinase-and toll-like receptor … J Norseen, T Hosooka, A Hammarstedt, MM Yore, S Kant, P Aryal, ... Molecular and cellular biology 32 (10), 2010-2019, 2012 | 272 | 2012 |
Palmitic acid hydroxystearic acids activate GPR40, which is involved in their beneficial effects on glucose homeostasis I Syed, J Lee, PM Moraes-Vieira, CJ Donaldson, A Sontheimer, P Aryal, ... Cell metabolism 27 (2), 419-427. e4, 2018 | 169 | 2018 |
Liver retinol transporter and receptor for serum retinol-binding protein (RBP4) P Alapatt, F Guo, SM Komanetsky, S Wang, J Cai, A Sargsyan, ER Díaz, ... Journal of Biological Chemistry 288 (2), 1250-1265, 2013 | 165 | 2013 |
Absence of carbohydrate response element binding protein in adipocytes causes systemic insulin resistance and impairs glucose transport A Vijayakumar, P Aryal, J Wen, I Syed, RP Vazirani, PM Moraes-Vieira, ... Cell reports 21 (4), 1021-1035, 2017 | 141 | 2017 |
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) protect against colitis by regulating gut innate and adaptive immune responses J Lee, PM Moraes-Vieira, A Castoldi, P Aryal, EU Yee, C Vickers, ... Journal of biological chemistry 291 (42), 22207-22217, 2016 | 126 | 2016 |
Obesity-linked PPARγ S273 phosphorylation promotes insulin resistance through growth differentiation factor 3 JA Hall, D Ramachandran, HC Roh, JR DiSpirito, T Belchior, PJH Zushin, ... Cell metabolism 32 (4), 665-675. e6, 2020 | 77 | 2020 |
A postsynaptic AMPK→ p21-activated kinase pathway drives fasting-induced synaptic plasticity in AgRP neurons D Kong, Y Dagon, JN Campbell, Y Guo, Z Yang, X Yi, P Aryal, ... Neuron 91 (1), 25-33, 2016 | 76 | 2016 |
Antigen presentation and T-cell activation are critical for RBP4-induced insulin resistance PM Moraes-Vieira, A Castoldi, P Aryal, K Wellenstein, OD Peroni, ... Diabetes 65 (5), 1317-1327, 2016 | 65 | 2016 |
Retinol binding protein 4 primes the NLRP3 inflammasome by signaling through Toll-like receptors 2 and 4 PM Moraes-Vieira, MM Yore, A Sontheimer-Phelps, A Castoldi, J Norseen, ... Proceedings of the National Academy of Sciences 117 (49), 31309-31318, 2020 | 61 | 2020 |
RBP4 increases lipolysis in human adipocytes and is associated with increased lipolysis and hepatic insulin resistance in obese women M Kilicarslan, BA de Weijer, KS Sjödin, P Aryal, KW Ter Horst, H Cakir, ... The FASEB Journal 34 (5), 6099, 2020 | 52 | 2020 |
Distinct biological activities of isomers from several families of branched fatty acid esters of hydroxy fatty acids (FAHFAs) P Aryal, I Syed, J Lee, R Patel, AT Nelson, D Siegel, A Saghatelian, ... Journal of lipid research 62, 2021 | 44 | 2021 |
High-throughput mediation analysis of human proteome and metabolome identifies mediators of post-bariatric surgical diabetes control JM Dreyfuss, Y Yuchi, X Dong, V Efthymiou, H Pan, DC Simonson, ... Nature communications 12 (1), 6951, 2021 | 19 | 2021 |
RBP4 inhibits insulin signaling in adipocytes by inducing pro-inflammatory cytokines in macrophages through a JNK-and TLR4-dependent and retinol-independent mechanism J Norseen, T Hosooka, A Hammarstedt, MM Yore, S Kant, P Aryal, ... Diabetes 61, A85-A85, 2012 | 4 | 2012 |
Doxorubicin Resistance in a Small Cell Lung Cancer Cell Line Can be Abolished by SiRNA Down-regulation of Cox 1 P Aryal Ball State University, 2007 | 2 | 2007 |
Retinol-binding protein 4 (RBP4) signals through TLR2 and TLR4/MD2 MM Yore, P Aryal, BB Kahn Diabetes 61, A423-A424, 2012 | 1 | 2012 |
Sero-prevalence of Newcastle disease virus (NDV) specific antibody in chicken. P Aryal, KM Hossain, MM Ahasan, KMD Islam, MM Billah, ME Islam, ... | 1 | 2003 |
1765-P: Inhibition of NLRP3 Inflammasome Activation and Reduction in T-Cell Migration Are Key Mechanisms by Which PAHSAs Protect against Type 1 Diabetes I SYED, VG MAGUPALLI, P ARYAL, A SANTORO, D SIEGEL, BB KAHN Diabetes 73 (Supplement_1), 2024 | | 2024 |
125-OR: New Lipid Biomarkers for Worsening Glucose Tolerance in Nondiabetic Relatives of People with Type 2 Diabetes I SYED, K SLUIS, P ARYAL, Z SOLOMON, R PATEL, S KONDURI, ... Diabetes 73 (Supplement_1), 2024 | | 2024 |
Novel mediation analysis of human plasma proteome and metabolome reveals mediators of improved glycemia after gastric bypass surgery JM Dreyfuss, Y Yuchi, H Pan, X Dong, DC Simonson, A Vernon, P Aryal, ... bioRxiv, 817494, 2019 | | 2019 |