Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts TK Karikari, TA Pascoal, NJ Ashton, S Janelidze, AL Benedet, ... The Lancet Neurology 19 (5), 422-433, 2020 | 909 | 2020 |
Association of cerebrospinal fluid neurofilament light protein levels with cognition in patients with dementia, motor neuron disease, and movement disorders B Olsson, E Portelius, NC Cullen, Å Sandelius, H Zetterberg, ... JAMA neurology 76 (3), 318-325, 2019 | 210 | 2019 |
Marked increase of β-amyloid(1–42) and amyloid precursor protein in ventricular cerebrospinal fluid after severe traumatic brain injury A Olsson, L Csajbok, M Öst, K Höglund, K Nylén, L Rosengren, ... Journal of neurology 251, 870-876, 2004 | 181 | 2004 |
Measurement of α-and β-secretase cleaved amyloid precursor protein in cerebrospinal fluid from Alzheimer patients A Olsson, K Höglund, M Sjögren, N Andreasen, L Minthon, L Lannfelt, ... Experimental neurology 183 (1), 74-80, 2003 | 181 | 2003 |
Cerebrospinal fluid neurogranin concentration in neurodegeneration: relation to clinical phenotypes and neuropathology E Portelius, B Olsson, K Höglund, NC Cullen, H Kvartsberg, ... Acta neuropathologica 136, 363-376, 2018 | 172 | 2018 |
Synaptic proteins predict cognitive decline in Alzheimer's disease and Lewy body dementia E Bereczki, PT Francis, D Howlett, JB Pereira, K Höglund, A Bogstedt, ... Alzheimer's & Dementia 12 (11), 1149-1158, 2016 | 166 | 2016 |
An update on blood-based biomarkers for non-Alzheimer neurodegenerative disorders NJ Ashton, A Hye, AP Rajkumar, A Leuzy, S Snowden, M Suárez-Calvet, ... Nature Reviews Neurology 16 (5), 265-284, 2020 | 161 | 2020 |
Increased plasma neurofilament light chain concentration correlates with severity of post-mortem neurofibrillary tangle pathology and neurodegeneration NJ Ashton, A Leuzy, YM Lim, C Troakes, T Hortobágyi, K Höglund, ... Acta neuropathologica communications 7, 1-11, 2019 | 159 | 2019 |
Novel tau fragments in cerebrospinal fluid: relation to tangle pathology and cognitive decline in Alzheimer’s disease C Cicognola, G Brinkmalm, J Wahlgren, E Portelius, J Gobom, NC Cullen, ... Acta neuropathologica 137, 279-296, 2019 | 156 | 2019 |
A new enzyme-linked immunosorbent assay for neurofilament light in cerebrospinal fluid: analytical validation and clinical evaluation L Gaetani, K Höglund, L Parnetti, F Pujol-Calderon, B Becker, P Eusebi, ... Alzheimer's research & therapy 10, 1-13, 2018 | 145 | 2018 |
Microglial markers are elevated in the prodromal phase of Alzheimer's disease and vascular dementia B Olsson, J Hertze, R Lautner, H Zetterberg, K Nägga, K Höglund, ... Journal of Alzheimer's Disease 33 (1), 45-53, 2013 | 138 | 2013 |
Plasma levels of β-amyloid (1-40), β-amyloid (1-42), and total β-amyloid remain unaffected in adult patients with hypercholesterolemia after treatment with statins K Höglund, O Wiklund, H Vanderstichele, O Eikenberg, E Vanmechelen, ... Archives of neurology 61 (3), 333-337, 2004 | 136 | 2004 |
The effect of simvastatin treatment on the amyloid precursor protein and brain cholesterol metabolism in patients with Alzheimer’s disease K Höglund, KM Thelen, S Syversen, M Sjögren, K Von Bergmann, ... Dementia and geriatric cognitive disorders 19 (5-6), 256-265, 2005 | 119 | 2005 |
Neurochemical aftermath of repetitive mild traumatic brain injury P Shahim, Y Tegner, B Gustafsson, M Gren, J Ärlig, M Olsson, N Lehto, ... JAMA neurology 73 (11), 1308-1315, 2016 | 116 | 2016 |
Prevalence of preclinical Alzheimer disease: Comparison of current classification systems S Kern, H Zetterberg, J Kern, A Zettergren, M Waern, K Höglund, ... Neurology 90 (19), e1682-e1691, 2018 | 113 | 2018 |
Characterization of tau in cerebrospinal fluid using mass spectrometry E Portelius, SF Hansson, AJ Tran, H Zetterberg, P Grognet, ... The Journal of Proteome Research 7 (5), 2114-2120, 2008 | 92 | 2008 |
Effect of HMG-CoA reductase inhibitors on β-amyloid peptide levels: implications for Alzheimer’s disease K Höglund, K Blennow CNS drugs 21, 449-462, 2007 | 90 | 2007 |
The intact postsynaptic protein neurogranin is reduced in brain tissue from patients with familial and sporadic Alzheimer’s disease H Kvartsberg, T Lashley, CE Murray, G Brinkmalm, NC Cullen, K Höglund, ... Acta Neuropathologica 137, 89-102, 2019 | 85 | 2019 |
Cerebrospinal fluid tau fragment correlates with tau PET: a candidate biomarker for tangle pathology K Blennow, C Chen, C Cicognola, KR Wildsmith, PT Manser, ... Brain 143 (2), 650-660, 2020 | 84 | 2020 |
Preclinical amyloid pathology biomarker positivity: effects on tau pathology and neurodegeneration K Höglund, S Kern, A Zettergren, A Börjesson-Hansson, H Zetterberg, ... Translational psychiatry 7 (1), e995-e995, 2017 | 76 | 2017 |