An insight into FDA approved antibody-drug conjugates for cancer therapy JTW Tong, PWR Harris, MA Brimble, I Kavianinia Molecules 26 (19), 5847, 2021 | 197 | 2021 |
Structural basis for receptor activity-modifying protein-dependent selective peptide recognition by a G protein-coupled receptor JM Booe, CS Walker, J Barwell, G Kuteyi, J Simms, MA Jamaluddin, ... Molecular cell 58 (6), 1040-1052, 2015 | 124 | 2015 |
A one-pot approach to neoglycopeptides using orthogonal native chemical ligation and click chemistry DJ Lee, K Mandal, PWR Harris, MA Brimble, SBH Kent Organic Letters 11 (22), 5270-5273, 2009 | 95 | 2009 |
Direct Peptide Lipidation through Thiol–Ene Coupling Enables Rapid Synthesis and Evaluation of Self‐Adjuvanting Vaccine Candidates TH Wright, AES Brooks, AJ Didsbury, GM Williams, PWR Harris, ... Angewandte Chemie International Edition 52 (40), 10616-10619, 2013 | 78 | 2013 |
NKT cell-dependent glycolipid–peptide vaccines with potent anti-tumour activity RJ Anderson, BJ Compton, C Tang, A Authier-Hall, CM Hayman, ... Chemical science 6 (9), 5120-5127, 2015 | 73 | 2015 |
Statistical affect detection in collaborative chat M Brooks, K Kuksenok, MK Torkildson, D Perry, JJ Robinson, TJ Scott, ... Proceedings of the 2013 conference on Computer supported cooperative work …, 2013 | 71 | 2013 |
Peripheral administration of a novel diketopiperazine, NNZ 2591, prevents brain injury and improves somatosensory-motor function following hypoxia–ischemia in adult rats J Guan, S Mathai, P Harris, JY Wen, R Zhang, M Brimble, P Gluckman Neuropharmacology 53 (6), 749-762, 2007 | 68 | 2007 |
Synthesis of cyclic proline-containing peptides via ring-closing metathesis PWR Harris, MA Brimble, PD Gluckman Organic Letters 5 (11), 1847-1850, 2003 | 67 | 2003 |
Characterizing the mode of action of extracellular Connexin43 channel blocking mimetic peptides in an in vitro ischemia injury model Y Kim, JM Griffin, PWR Harris, SHC Chan, LFB Nicholson, MA Brimble, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (2), 68-78, 2017 | 62 | 2017 |
An improved procedure for the preparation of aminomethyl polystyrene resin and its use in solid phase (peptide) synthesis PWR Harris, SH Yang, MA Brimble Tetrahedron letters 52 (45), 6024-6026, 2011 | 62 | 2011 |
Amylin analog pramlintide induces migraine‐like attacks in patients H Ghanizada, MAM Al‐Karagholi, CS Walker, N Arngrim, T Rees, ... Annals of neurology 89 (6), 1157-1171, 2021 | 61 | 2021 |
Supplementation of blackcurrant anthocyanins increased cyclic glycine-proline in the cerebrospinal fluid of Parkinson patients: Potential treatment to improve insulin-like … D Fan, Y Alamri, K Liu, M MacAskill, P Harris, M Brimble, ... Nutrients 10 (6), 714, 2018 | 58 | 2018 |
Enhancing the oral bioavailability of peptide drugs by using chemical modification and other approaches N Yin, MA Brimble, PWR Harris, J Wen Med. Chem 4 (12), 763-769, 2014 | 57 | 2014 |
NNZ-2566: A Gly–Pro–Glu analogue with neuroprotective efficacy in a rat model of acute focal stroke MJ Bickerdike, GB Thomas, DC Batchelor, ES Sirimanne, W Leong, H Lin, ... Journal of the neurological sciences 278 (1-2), 85-90, 2009 | 57 | 2009 |
Radiation damage and racemic protein crystallography reveal the unique structure of the GASA/Snakin protein superfamily H Yeung, CJ Squire, Y Yosaatmadja, S Panjikar, G López, A Molina, ... Angewandte Chemie 128 (28), 8062-8065, 2016 | 54 | 2016 |
Total synthesis of the cyclic depsipeptide YM-280193, a platelet aggregation inhibitor H Kaur, PWR Harris, PJ Little, MA Brimble Organic letters 17 (3), 492-495, 2015 | 54 | 2015 |
Molecular signature for receptor engagement in the metabolic peptide hormone amylin RL Bower, L Yule, TA Rees, G Deganutti, ER Hendrikse, PWR Harris, ... ACS Pharmacology & Translational Science 1 (1), 32-49, 2018 | 53 | 2018 |
Synthesis of proline-modified analogues of the neuroprotective agent glycyl-l-prolyl-glutamic acid (GPE) PWR Harris, MA Brimble, VJ Muir, MYH Lai, NS Trotter, DJ Callis Tetrahedron 61 (42), 10018-10035, 2005 | 52 | 2005 |
Peptide lipidation–a synthetic strategy to afford peptide based therapeutics R Kowalczyk, PWR Harris, GM Williams, SH Yang, MA Brimble Peptides and peptide-based biomaterials and their biomedical applications …, 2017 | 51 | 2017 |
The role for IGF-1-derived small neuropeptides as a therapeutic target for neurological disorders J Guan, P Harris, M Brimble, Y Lei, J Lu, Y Yang, AJ Gunn Expert opinion on therapeutic targets 19 (6), 785-793, 2015 | 51 | 2015 |