Direct targeting of β-catenin by a small molecule stimulates proteasomal degradation and suppresses oncogenic Wnt/β-catenin signaling SY Hwang, X Deng, S Byun, C Lee, SJ Lee, H Suh, J Zhang, Q Kang, ... Cell reports 16 (1), 28-36, 2016 | 129 | 2016 |
RIPK1-mediated induction of mitophagy compromises the viability of extracellular-matrix-detached cells MA Hawk, CL Gorsuch, P Fagan, C Lee, SE Kim, JC Hamann, JA Mason, ... Nature cell biology 20 (3), 272-284, 2018 | 90 | 2018 |
Selective lysosome membrane turnover is induced by nutrient starvation C Lee, L Lamech, E Johns, M Overholtzer Developmental cell 55 (3), 289-297. e4, 2020 | 57 | 2020 |
Suramin inhibits cullin-RING E3 ubiquitin ligases K Wu, RA Chong, Q Yu, J Bai, DE Spratt, K Ching, C Lee, H Miao, I Tappin, ... Proceedings of the National Academy of Sciences 113 (14), E2011-E2018, 2016 | 54 | 2016 |
Pivotal role for the ubiquitin Y59-E51 loop in lysine 48 polyubiquitination RA Chong, K Wu, DE Spratt, Y Yang, C Lee, J Nayak, M Xu, R Elkholi, ... Proceedings of the National Academy of Sciences 111 (23), 8434-8439, 2014 | 30 | 2014 |
A snapshot of ubiquitin chain elongation: Lysine 48-tetra-ubiquitin slows down ubiquitination J Kovacev, K Wu, DE Spratt, RA Chong, C Lee, J Nayak, GS Shaw, ... Journal of Biological Chemistry 289 (10), 7068-7081, 2014 | 13 | 2014 |
Stress-induced microautophagy is coordinated with lysosome biogenesis and regulated by PIKfyve AD Klein, KL Petruzzi, C Lee, M Overholtzer Molecular Biology of the Cell 35 (5), ar70, 2024 | 2 | 2024 |
Principles of paralog-specific targeted protein degradation engaging the C-degron E3 KLHDC2 DC Scott, S Dharuman, E Griffith, SC Chai, J Ronnebaum, MT King, ... Nature Communications 15 (1), 8829, 2024 | | 2024 |
Getting picky with the lysosome membrane C Lee, M Overholtzer Autophagy 17 (4), 1034-1036, 2021 | | 2021 |