Anti-angiogenic therapy: current challenges and future perspectives F Lopes-Coelho, F Martins, SA Pereira, J Serpa International journal of molecular sciences 22 (7), 3765, 2021 | 188 | 2021 |
Cysteine metabolic circuitries: Druggable targets in cancer VDB Bonifácio, SA Pereira, J Serpa, JB Vicente British journal of cancer 124 (5), 862-879, 2021 | 135 | 2021 |
Cysteine allows ovarian cancer cells to adapt to hypoxia and to escape from carboplatin cytotoxicity SC Nunes, C Ramos, F Lopes-Coelho, CO Sequeira, F Silva, ... Scientific reports 8 (1), 9513, 2018 | 68 | 2018 |
HNF1β drives glutathione (GSH) synthesis underlying intrinsic carboplatin resistance of ovarian clear cell carcinoma (OCCC) F Lopes-Coelho, S Gouveia-Fernandes, LG Gonçalves, C Nunes, ... Tumor Biology 37, 4813-4829, 2016 | 65 | 2016 |
Development and validation of an assay for the simultaneous determination of zidovudine, abacavir, emtricitabine, lamivudine, tenofovir and ribavirin in human plasma using … W Kromdijk, SA Pereira, H Rosing, JW Mulder, JH Beijnen, ADR Huitema Journal of Chromatography B 919, 43-51, 2013 | 56 | 2013 |
Evidence for nevirapine bioactivation in man: searching for the first step in the mechanism of nevirapine toxicity U Caixas, AMM Antunes, AT Marinho, ALA Godinho, NM Grilo, ... Toxicology 301 (1-3), 33-39, 2012 | 50 | 2012 |
Targeting glutathione and cystathionine β-synthase in ovarian cancer treatment by selenium–chrysin polyurea dendrimer nanoformulation I Santos, C Ramos, C Mendes, CO Sequeira, CS Tomé, DGH Fernandes, ... Nutrients 11 (10), 2523, 2019 | 44 | 2019 |
Monocytes as endothelial progenitor cells (EPCs), another brick in the wall to disentangle tumor angiogenesis F Lopes-Coelho, F Silva, S Gouveia-Fernandes, C Martins, N Lopes, ... Cells 9 (1), 107, 2020 | 40 | 2020 |
Usefulness of zebrafish larvae to evaluate drug-induced functional and morphological renal tubular alterations R Gorgulho, R Jacinto, SS Lopes, SA Pereira, EM Tranfield, GG Martins, ... Archives of toxicology 92 (1), 411-423, 2018 | 36 | 2018 |
Differences in nevirapine biotransformation as a factor for its sex-dependent dimorphic profile of adverse drug reactions AT Marinho, PM Rodrigues, U Caixas, AMM Antunes, T Branco, ... Journal of antimicrobial chemotherapy 69 (2), 476-482, 2014 | 36 | 2014 |
Long‐term and concentration‐dependent beneficial effect of efavirenz on HDL‐cholesterol in HIV‐infected patients SA Pereira, T Branco, RM Côrte‐Real, I Germano, F Lampreia, U Caixas, ... British journal of clinical pharmacology 61 (5), 601-604, 2006 | 36 | 2006 |
Voluntary oral administration of losartan in rats LN Diogo, IV Faustino, RA Afonso, SA Pereira, EC Monteiro, AI Santos Journal of the American Association for Laboratory Animal Science 54 (5 …, 2015 | 34 | 2015 |
Reactive aldehyde metabolites from the anti-HIV drug abacavir: amino acid adducts as possible factors in abacavir toxicity C Charneira, ALA Godinho, MC Oliveira, SA Pereira, EC Monteiro, ... Chemical research in toxicology 24 (12), 2129-2141, 2011 | 34 | 2011 |
Hepatocyte spheroids as a competent in vitro system for drug biotransformation studies: nevirapine as a bioactivation case study PF Pinheiro, SA Pereira, SG Harjivan, IL Martins, AT Marinho, M Cipriano, ... Archives of toxicology 91, 1199-1211, 2017 | 32 | 2017 |
Unmasking efavirenz neurotoxicity: Time matters to the underlying mechanisms NM Grilo, MJ Correia, JP Miranda, M Cipriano, J Serpa, MM Marques, ... European Journal of Pharmaceutical Sciences 105, 47-54, 2017 | 31 | 2017 |
Monitoring abacavir bioactivation in humans: screening for an aldehyde metabolite NM Grilo, AMM Antunes, U Caixas, AT Marinho, C Charneira, MC Oliveira, ... Toxicology letters 219 (1), 59-64, 2013 | 31 | 2013 |
Cysteine boosters the evolutionary adaptation to CoCl2 mimicked hypoxia conditions, favouring carboplatin resistance in ovarian cancer SC Nunes, F Lopes-Coelho, S Gouveia-Fernandes, C Ramos, SA Pereira, ... BMC Evolutionary Biology 18, 1-17, 2018 | 30 | 2018 |
Implications of sulfotransferase activity in interindividual variability in drug response: clinical perspective on current knowledge N Marto, J Morello, EC Monteiro, SA Pereira Drug metabolism reviews 49 (3), 357-371, 2017 | 29 | 2017 |
Bioactivation to an aldehyde metabolite—possible role in the onset of toxicity induced by the anti-HIV drug abacavir NM Grilo, C Charneira, SA Pereira, EC Monteiro, MM Marques, ... Toxicology letters 224 (3), 416-423, 2014 | 29 | 2014 |
Efavirenz concentrations in HIV‐infected patients with and without viral hepatitis SA Pereira, U Caixas, T Branco, I Germano, F Lampreia, AL Papoila, ... British journal of clinical pharmacology 66 (4), 551-555, 2008 | 28 | 2008 |