| Increase in signal-to-noise ratio of> 10,000 times in liquid-state NMR JH Ardenkjær-Larsen, B Fridlund, A Gram, G Hansson, L Hansson, ... Proceedings of the National Academy of Sciences 100 (18), 10158-10163, 2003 | 3207 | 2003 |
| Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy SE Day, MI Kettunen, FA Gallagher, DE Hu, M Lerche, J Wolber, ... Nature medicine 13 (11), 1382-1387, 2007 | 1023 | 2007 |
| Magnetic resonance imaging of pH in vivo using hyperpolarized 13C-labelled bicarbonate FA Gallagher, MI Kettunen, SE Day, DE Hu, JH Ardenkjær-Larsen, ... Nature 453 (7197), 940-943, 2008 | 942 | 2008 |
| Metabolic Imaging by Hyperpolarized 13C Magnetic Resonance Imaging for In vivo Tumor Diagnosis K Golman, R Zandt, M Lerche, R Pehrson, JH Ardenkjaer-Larsen Cancer research 66 (22), 10855-10860, 2006 | 666 | 2006 |
| Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors FA Gallagher, MI Kettunen, DE Hu, PR Jensen, R Zandt, M Karlsson, ... Proceedings of the National Academy of Sciences 106 (47), 19801-19806, 2009 | 369 | 2009 |
| Generating highly polarized nuclear spins in solution using dynamic nuclear polarization J Wolber, F Ellner, B Fridlund, A Gram, H Johannesson, G Hansson, ... Nuclear Instruments and Methods in Physics Research Section A: Accelerators …, 2004 | 212 | 2004 |
| 13C MR spectroscopy measurements of glutaminase activity in human hepatocellular carcinoma cells using hyperpolarized 13C‐labeled glutamine FA Gallagher, MI Kettunen, SE Day, M Lerche, KM Brindle Magnetic Resonance in Medicine: An Official Journal of the International …, 2008 | 201 | 2008 |
| Barley lipid-transfer protein complexed with palmitoyl CoA: the structure reveals a hydrophobic binding site that can expand to fit both large and small lipid-like ligands MH Lerche, BB Kragelund, LM Bech, FM Poulsen Structure 5 (2), 291-306, 1997 | 147 | 1997 |
| Identification of a neuritogenic ligand of the neural cell adhesion molecule using a combinatorial library of synthetic peptides LCB Rønn, M Olsen, S Østergaard, V Kiselyov, V Berezin, MT Mortensen, ... Nature biotechnology 17 (10), 1000-1005, 1999 | 143 | 1999 |
| Non-invasive in-cell determination of free cytosolic [NAD+]/[NADH] ratios using hyperpolarized glucose show large variations in metabolic phenotypes CE Christensen, M Karlsson, JR Winther, PR Jensen, MH Lerche Journal of Biological Chemistry 289 (4), 2344-2352, 2014 | 125 | 2014 |
| Solution structure of barley lipid transfer protein complexed with palmitate. Two different binding modes of palmitate in the homologous maize and barley nonspecific lipid … MH Lerche, FM Poulsen Protein Science 7 (12), 2490-2498, 1998 | 119 | 1998 |
| Metabolic pathway visualization in living yeast by DNP-NMR S Meier, M Karlsson, PR Jensen, MH Lerche, JØ Duus Molecular BioSystems 7 (10), 2834-2836, 2011 | 115 | 2011 |
| Tissue-specific short chain fatty acid metabolism and slow metabolic recovery after ischemia from hyperpolarized NMR in vivo PR Jensen, T Peitersen, M Karlsson, A Gisselsson, G Hansson, S Meier, ... Journal of Biological Chemistry 284 (52), 36077-36082, 2009 | 90 | 2009 |
| Detection of tumor glutamate metabolism in vivo using 13C magnetic resonance spectroscopy and hyperpolarized [1‐13C]glutamate FA Gallagher, MI Kettunen, SE Day, D Hu, M Karlsson, A Gisselsson, ... Magnetic resonance in medicine 66 (1), 18-23, 2011 | 89 | 2011 |
| Development of dissolution DNP-MR substrates for metabolic research M Karlsson, PR Jensen, JØ Duus, S Meier, MH Lerche Applied Magnetic Resonance 43, 223-236, 2012 | 77 | 2012 |
| Imaging of branched chain amino acid metabolism in tumors with hyperpolarized 13C ketoisocaproate M Karlsson, PR Jensen, R in't Zandt, A Gisselsson, G Hansson, JØ Duus, ... International journal of cancer 127 (3), 729-736, 2010 | 77 | 2010 |
| Pulse sequences for measurement of one-bond 15N–1H coupling constants in the protein backbone MH Lerche, A Meissner, FM Poulsen, OW Sørensen Journal of Magnetic Resonance 140 (1), 259-263, 1999 | 76 | 1999 |
| Study of molecular interactions with 13C DNP-NMR MH Lerche, S Meier, PR Jensen, H Baumann, BO Petersen, M Karlsson, ... Journal of Magnetic Resonance 203 (1), 52-56, 2010 | 73 | 2010 |
| Hyperpolarized amino acids for in vivo assays of transaminase activity PR Jensen, M Karlsson, S Meier, JØ Duus, MH Lerche Chemistry–A European Journal 15 (39), 10010-10012, 2009 | 69 | 2009 |
| Hyperpolarized NMR probes for biological assays S Meier, PR Jensen, M Karlsson, MH Lerche Sensors 14 (1), 1576-1597, 2014 | 68 | 2014 |
