RNA ligase RtcB splices 3′-phosphate and 5′-OH ends via covalent RtcB-(histidinyl)-GMP and polynucleotide-(3′) pp (5′) G intermediates AK Chakravarty, R Subbotin, BT Chait, S Shuman Proceedings of the National Academy of Sciences 109 (16), 6072-6077, 2012 | 113 | 2012 |
Novel mechanism of RNA repair by RtcB via sequential 2′, 3′-cyclic phosphodiesterase and 3′-phosphate/5′-hydroxyl ligation reactions N Tanaka, AK Chakravarty, B Maughan, S Shuman Journal of Biological Chemistry 286 (50), 43134-43143, 2011 | 109 | 2011 |
A non-amyloid prion particle that activates a heritable gene expression program AK Chakravarty, T Smejkal, AK Itakura, DM Garcia, DF Jarosz Molecular cell 77 (2), 251-265. e9, 2020 | 93 | 2020 |
Comprehensive and quantitative mapping of RNA–protein interactions across a transcribed eukaryotic genome R She, AK Chakravarty, CJ Layton, LM Chircus, JOL Andreasson, ... Proceedings of the National Academy of Sciences 114 (14), 3619-3624, 2017 | 73 | 2017 |
A prion epigenetic switch establishes an active chromatin state ZH Harvey, AK Chakravarty, RA Futia, DF Jarosz Cell 180 (5), 928-940. e14, 2020 | 71 | 2020 |
The sequential 2′, 3′-cyclic phosphodiesterase and 3′-phosphate/5′-OH ligation steps of the RtcB RNA splicing pathway are GTP-dependent AK Chakravarty, S Shuman Nucleic acids research 40 (17), 8558-8567, 2012 | 58 | 2012 |
Widespread prion-based control of growth and differentiation strategies in Saccharomyces cerevisiae AK Itakura, AK Chakravarty, CM Jakobson, DF Jarosz Molecular cell 77 (2), 266-278. e6, 2020 | 49 | 2020 |
More than just a phase: prions at the crossroads of epigenetic inheritance and evolutionary change AK Chakravarty, DF Jarosz Journal of molecular biology 430 (23), 4607-4618, 2018 | 47 | 2018 |
RNA 3′-phosphate cyclase (RtcA) catalyzes ligase-like adenylylation of DNA and RNA 5′-monophosphate ends AK Chakravarty, S Shuman Journal of biological chemistry 286 (6), 4117-4122, 2011 | 40 | 2011 |
Rewriting the rules for end joining via enzymatic splicing of DNA 3′-PO4 and 5′-OH ends U Das, AK Chakravarty, BS Remus, S Shuman Proceedings of the National Academy of Sciences 110 (51), 20437-20442, 2013 | 36 | 2013 |
Structure, mechanism, and specificity of a eukaryal tRNA restriction enzyme involved in self-nonself discrimination AK Chakravarty, P Smith, R Jalan, S Shuman Cell reports 7 (2), 339-347, 2014 | 21 | 2014 |
Structures of RNA 3′-phosphate cyclase bound to ATP reveal the mechanism of nucleotidyl transfer and metal-assisted catalysis AK Chakravarty, P Smith, S Shuman Proceedings of the National Academy of Sciences 108 (52), 21034-21039, 2011 | 18 | 2011 |
Substrate specificity and mutational analysis of Kluyveromyces lactis γ-toxin, a eukaryal tRNA anticodon nuclease R Jain, MG Poulos, J Gros, AK Chakravarty, S Shuman RNA 17 (7), 1336-1343, 2011 | 15 | 2011 |
Biomolecular condensation: a new phase in cancer research AK Chakravarty, DJ McGrail, TM Lozanoski, BS Dunn, DJH Shih, ... Cancer discovery 12 (9), 2031-2043, 2022 | 7 | 2022 |
Mechanisms of RNA damage and repair AK Chakravarty Weill Medical College of Cornell University, 2014 | | 2014 |
Rewriting the rules for end joining via enzymatic splicing of DNA 3′-PO₄ and 5′-OH ends U Das, AK Chakravarty, BS Remus, S Shuman | | 2013 |