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SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate D Olagnier, E Farahani, J Thyrsted, J Blay-Cadanet, A Herengt, M Idorn, ... Nature communications 11 (1), 4938, 2020 | 367 | 2020 |
Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming D Olagnier, AM Brandtoft, C Gunderstofte, NL Villadsen, C Krapp, ... Nature communications 9 (1), 3506, 2018 | 240 | 2018 |
Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors KA Horan, K Hansen, MR Jakobsen, CK Holm, S Søby, L Unterholzner, ... The Journal of Immunology 190 (5), 2311-2319, 2013 | 229 | 2013 |
Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling AL Hansen, GJ Buchan, M Rühl, K Mukai, SR Salvatore, E Ogawa, ... Proceedings of the National Academy of Sciences 115 (33), E7768-E7775, 2018 | 201 | 2018 |
TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice LS Reinert, L Harder, CK Holm, MB Iversen, KA Horan, ... The Journal of clinical investigation 122 (4), 1368-1376, 2012 | 190 | 2012 |
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Expression of type III interferon (IFN) in the vaginal mucosa is mediated primarily by dendritic cells and displays stronger dependence on NF-κB than type I IFNs MB Iversen, N Ank, J Melchjorsen, SR Paludan Journal of virology 84 (9), 4579-4586, 2010 | 110 | 2010 |
An innate antiviral pathway acting before interferons at epithelial surfaces MB Iversen, LS Reinert, MK Thomsen, I Bagdonaite, R Nandakumar, ... Nature immunology 17 (2), 150-158, 2016 | 82 | 2016 |
A STING antagonist modulating the interaction with STIM1 blocks ER-to-Golgi trafficking and inhibits lupus pathology T Prabakaran, A Troldborg, S Kumpunya, I Alee, E Marinković, ... EBioMedicine 66, 2021 | 47 | 2021 |
Extracellular superoxide dismutase is present in secretory vesicles of human neutrophils and released upon stimulation MB Iversen, RH Gottfredsen, UG Larsen, JJ Enghild, J Praetorius, ... Free Radical Biology and Medicine 97, 478-488, 2016 | 45 | 2016 |
Nrf2 negatively regulates type I interferon responses and increases susceptibility to herpes genital infection in mice C Gunderstofte, MB Iversen, S Peri, A Thielke, S Balachandran, CK Holm, ... Frontiers in immunology 10, 2101, 2019 | 35 | 2019 |
Resveratrol displays anti-inflammatory properties in an ex vivo model of immune mediated inflammatory arthritis S Lomholt, A Mellemkjær, MB Iversen, SB Pedersen, TW Kragstrup BMC rheumatology 2, 1-10, 2018 | 25 | 2018 |
NKT cell activation by local α-galactosylceramide administration decreases susceptibility to HSV-2 infection MB Iversen, SK Jensen, AL Hansen, H Winther, S Issazadeh-Navikas, ... Immunobiology 220 (6), 762-768, 2015 | 14 | 2015 |
Interleukin-21 receptor signalling is important for innate immune protection against HSV-2 infections SK Kratholm, MB Iversen, L Reinert, SK Jensen, M Hokland, T Andersen, ... PloS one 8 (12), e81790, 2013 | 14 | 2013 |
Expression of type III IFN in the vaginal mucosa is mediated primarily by DCs and displays stronger dependence on NF-{kappa} B than type I IFNs MB Iversen, N Ank, J Melchjorsen, SR Paludan J Virol 84 (9), 4579-4586, 2010 | 12 | 2010 |
Author Correction: SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate D Olagnier, E Farahani, J Thyrsted, J Blay-Cadanet, A Herengt, M Idorn, ... Nature Communications 11, 2020 | 8 | 2020 |
gnaes-Hansen F, Thomsen AR, Chen Z, Haugen H, Klucher K, Paludan SR. An important role for type III interferon (IFN-lambda/IL-28) in TLR-induced antiviral activity N Ank, MB Iversen, C Bartholdy, P Staeheli, R Hartmann, UB Jensen J Immunol 180, 2474-2485, 2008 | 5 | 2008 |
HSV-1 employs UL56 to antagonize expression and function of cGAMP channels HTW Blest, A Redmond, J Avissar, J Barker, A Bridgeman, G Fowler, ... Cell Reports 43 (5), 2024 | 3 | 2024 |
Identification of SARS-CoV-2-mediated suppression of NRF2 signaling reveals a potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate DP Olagnier, E Farahani, J Thyrsted, JB Cadanet, A Herengt, M Idorn, ... Research Square (27 May 2020) DOI 10, 2020 | 3 | 2020 |