CEACAM1-4S, a cell–cell adhesion molecule, mediates apoptosis and reverts mammary carcinoma cells to a normal morphogenic phenotype in a 3D culture J Kirshner, CJ Chen, P Liu, J Huang, JE Shively Proceedings of the National Academy of Sciences 100 (2), 521-526, 2003 | 209 | 2003 |
Inhibition of transforming growth factor-β1 signaling attenuates ataxia telangiectasia mutated activity in response to genotoxic stress J Kirshner, MF Jobling, MJ Pajares, SA Ravani, AB Glick, MJ Lavin, ... Cancer research 66 (22), 10861-10869, 2006 | 171 | 2006 |
A unique three-dimensional model for evaluating the impact of therapy on multiple myeloma J Kirshner, KJ Thulien, LD Martin, C Debes Marun, T Reiman, AR Belch, ... Blood, The Journal of the American Society of Hematology 112 (7), 2935-2945, 2008 | 151 | 2008 |
The natural products parthenolide and andrographolide exhibit anti-cancer stem cell activity in multiple myeloma EJ Gunn, JT Williams, DT Huynh, MJ Iannotti, C Han, FJ Barrios, ... Leukemia & lymphoma 52 (6), 1085-1097, 2011 | 101 | 2011 |
CEACAM1, a cell-cell adhesion molecule, directly associates with annexin II in a three-dimensional model of mammary morphogenesis J Kirshner, D Schumann, JE Shively Journal of Biological Chemistry 278 (50), 50338-50345, 2003 | 89 | 2003 |
Exploiting the facile release of trifluoroacetate for the α-methylenation of the sterically hindered carbonyl groups on (+)-sclareolide and (−)-eburnamonine MV Riofski, JP John, MM Zheng, J Kirshner, DA Colby The Journal of organic chemistry 76 (10), 3676-3683, 2011 | 63 | 2011 |
The systemic cytokine environment is permanently altered in multiple myeloma MM Zheng, Z Zhang, K Bemis, AR Belch, LM Pilarski, JE Shively, ... PloS one 8 (3), e58504, 2013 | 60 | 2013 |
Mutation analysis of the short cytoplasmic domain of the cell-cell adhesion molecule CEACAM1 identifies residues that orchestrate actin binding and lumen formation CJ Chen, J Kirshner, MA Sherman, W Hu, T Nguyen, JE Shively Journal of Biological Chemistry 282 (8), 5749-5760, 2007 | 58 | 2007 |
Altered expression of fibronectin and collagens I and IV in multiple myeloma and monoclonal gammopathy of undetermined significance TM Tancred, AR Belch, T Reiman, LM Pilarski, J Kirshner Journal of Histochemistry & Cytochemistry 57 (3), 239-247, 2009 | 47 | 2009 |
Cell–cell adhesion molecule CEACAM1 is expressed in normal breast and milk and associates with β1 integrin in a 3D model of morphogenesis J Kirshner, J Hardy, S Wilczynski, JE Shively Journal of molecular histology 35, 287-299, 2004 | 33 | 2004 |
N-cadherin impedes proliferation of the multiple myeloma cancer stem cells NM Sadler, BR Harris, BA Metzger, J Kirshner American journal of blood research 3 (4), 271, 2013 | 32 | 2013 |
1α, 25-dihydroxyvitamin D inhibits the metastatic capability of MCF10CA1a and MDA-MB-231 cells in an in vitro model of breast to bone metastasis T Wilmanski, A Barnard, MR Parikh, J Kirshner, K Buhman, J Burgess, ... Nutrition and cancer 68 (7), 1202-1209, 2016 | 30 | 2016 |
Dkk-1 and IL-7 in plasma of patients with multiple myeloma prevent differentiation of mesenchymal stem cells into osteoblasts BA Nierste, CA Glackin, J Kirshner American Journal of Blood Research 4 (2), 73, 2014 | 26 | 2014 |
Synthesis of 15-methylene-eburnamonine from (+)-vincamine, evaluation of anticancer activity, and investigation of mechanism of action by quantitative NMR JR Woods, MV Riofski, MM Zheng, MA O’Banion, H Mo, J Kirshner, ... Bioorganic & medicinal chemistry letters 23 (21), 5865-5869, 2013 | 25 | 2013 |
Inhibition of TGFbeta1 signaling attenutates ATM activity in response to genotoxic stress J Kirshner, MF Jobling, MJ Pajares, SA Ravani, AB Glick, MJ Lavin, ... | 22 | 2006 |
A three-dimensional tissue culture model to study primary human bone marrow and its malignancies MR Parikh, AR Belch, LM Pilarski, J Kirshner Journal of Visualized Experiments: Jove, 2014 | 15 | 2014 |
Differentiation of cancer cells in two-dimensional and three-dimensional breast cancer models by Raman spectroscopy NP Damayanti, Y Fang, MR Parikh, AP Craig, J Kirshner, J Irudayaraj Journal of biomedical optics 18 (11), 117008-117008, 2013 | 15 | 2013 |
A reconstructed metastasis model to recapitulate the metastatic spread in vitro MR Parikh, KE Minser, LM Rank, CA Glackin, J Kirshner Biotechnology journal 9 (9), 1129-1139, 2014 | 11 | 2014 |
TGFβ: roles in DNA damage responses KL Andarawewa, J Kirshner, JD Mott, MH Barcellos-Hoff Transforming Growth Factor-β in Cancer Therapy, Volume II: Cancer Treatment …, 2008 | 11 | 2008 |
Characterization of recombinant soluble carcinoembryonic antigen cell adhesion molecule 1 D Schumann, J Huang, PE Clarke, J Kirshner, S Tsai, VN Schumaker, ... Biochemical and biophysical research communications 318 (1), 227-233, 2004 | 11 | 2004 |