Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis F Liu, D Lagares, KM Choi, L Stopfer, A Marinković, V Vrbanac, CK Probst, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 308 (4 …, 2015 | 754 | 2015 |
Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis D Lagares, A Santos, PE Grasberger, F Liu, CK Probst, RA Rahimi, ... Science translational medicine 9 (420), eaal3765, 2017 | 195 | 2017 |
Type I collagen–targeted PET probe for pulmonary fibrosis detection and staging in preclinical models P Désogère, LF Tapias, LP Hariri, NJ Rotile, TA Rietz, CK Probst, F Blasi, ... Science translational medicine 9 (384), eaaf4696, 2017 | 129 | 2017 |
ADAM10-mediated ephrin-B2 shedding promotes myofibroblast activation and organ fibrosis D Lagares, P Ghassemi-Kakroodi, C Tremblay, A Santos, CK Probst, ... Nature medicine 23 (12), 1405-1415, 2017 | 123 | 2017 |
The Rho kinase isoforms ROCK1 and ROCK2 each contribute to the development of experimental pulmonary fibrosis RS Knipe, CK Probst, D Lagares, A Franklin, JJ Spinney, PL Brazee, ... American journal of respiratory cell and molecular biology 58 (4), 471-481, 2018 | 105 | 2018 |
An autotaxin/lysophosphatidic acid/interleukin‐6 amplification loop drives scleroderma fibrosis FV Castelino, G Bain, VA Pace, KE Black, L George, CK Probst, L Goulet, ... Arthritis & rheumatology 68 (12), 2964-2974, 2016 | 90 | 2016 |
Uncoupling of the profibrotic and hemostatic effects of thrombin in lung fibrosis BS Shea, CK Probst, PL Brazee, NJ Rotile, F Blasi, PH Weinreb, KE Black, ... JCI insight 2 (9), 2017 | 76 | 2017 |
Vascular permeability in the fibrotic lung CK Probst, SB Montesi, BD Medoff, BS Shea, RS Knipe European Respiratory Journal 56 (1), 2020 | 69 | 2020 |
Molecular imaging of oxidized collagen quantifies pulmonary and hepatic fibrogenesis HH Chen, PA Waghorn, L Wei, LF Tapias, DT Schühle, NJ Rotile, ... JCI insight 2 (11), 2017 | 61 | 2017 |
Sexually dimorphic role for vasopressin in the development of social play MJ Paul, JI Terranova, CK Probst, EK Murray, NI Ismail, GJ De Vries Frontiers in behavioral neuroscience 8, 58, 2014 | 56 | 2014 |
Molecular magnetic resonance imaging of lung fibrogenesis with an oxyamine‐based probe PA Waghorn, CM Jones, NJ Rotile, SK Koerner, DS Ferreira, HH Chen, ... Angewandte Chemie International Edition 56 (33), 9825-9828, 2017 | 54 | 2017 |
Autotaxin activity increases locally following lung injury, but is not required for pulmonary lysophosphatidic acid production or fibrosis KE Black, E Berdyshev, G Bain, FV Castelino, BS Shea, CK Probst, ... The FASEB Journal 30 (6), 2435, 2016 | 46 | 2016 |
Screening for YAP inhibitors identifies statins as modulators of fibrosis DM Santos, L Pantano, G Pronzati, P Grasberger, CK Probst, KE Black, ... American Journal of Respiratory Cell and Molecular Biology 62 (4), 479-492, 2020 | 42 | 2020 |
Endothelial-specific loss of sphingosine-1-phosphate receptor 1 increases vascular permeability and exacerbates bleomycin-induced pulmonary fibrosis RS Knipe, JJ Spinney, EA Abe, CK Probst, A Franklin, A Logue, ... American Journal of Respiratory Cell and Molecular Biology 66 (1), 38-52, 2022 | 27 | 2022 |
Lysophosphatidic acid signaling through the lysophosphatidic acid-1 receptor is required for alveolarization M Funke, L Knudsen, D Lagares, S Ebener, CK Probst, BA Fontaine, ... American journal of respiratory cell and molecular biology 55 (1), 105-116, 2016 | 26 | 2016 |
Dissociation of puberty and adolescent social development in a seasonally breeding species MJ Paul, CK Probst, LM Brown, GJ de Vries Current Biology 28 (7), 1116-1123. e2, 2018 | 25 | 2018 |
Peroxidase sensitive amplifiable probe for molecular magnetic resonance imaging of pulmonary inflammation A Rodríguez-Rodríguez, S Shuvaev, N Rotile, CM Jones, CK Probst, ... ACS sensors 4 (9), 2412-2419, 2019 | 20 | 2019 |
A tissue-bioengineering strategy for modeling rare human kidney diseases in vivo JOR Hernandez, X Wang, M Vazquez-Segoviano, M Lopez-Marfil, ... Nature communications 12 (1), 1-16, 2021 | 17 | 2021 |
Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model A Axelsson Raja, H Wakimoto, DM DeLaughter, D Reichart, J Gorham, ... Proceedings of the National Academy of Sciences 119 (28), e2204174119, 2022 | 10 | 2022 |
Therapeutic Targeting of DGKA-Mediated Macropinocytosis Leads to Phospholipid Reprogramming in Tuberous Sclerosis ComplexMacropinocytosis in TSC Is Regulated via DGKA A Kovalenko, A Sanin, K Kosmas, L Zhang, J Wang, EW Akl, K Giannikou, ... Cancer research 81 (8), 2086-2100, 2021 | 7 | 2021 |