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Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy RD Sentelle, CE Senkal, W Jiang, S Ponnusamy, S Gencer, ... Nature chemical biology 8 (10), 831-838, 2012 | 539 | 2012 |
Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A‐RIPK1‐dependent necroptosis SA Saddoughi, S Gencer, YK Peterson, KE Ward, A Mukhopadhyay, ... EMBO molecular medicine 5 (1), 105-121, 2013 | 296 | 2013 |
Biochemical Mechanisms of the Generation of Endogenous Long Chain Ceramide in Response to Exogenous Short Chain Ceramide in the A549 Human Lung Adenocarcinoma Cell Line: ROLE … B Ogretmen, BJ Pettus, MJ Rossi, R Wood, J Usta, Z Szulc, A Bielawska, ... Journal of Biological Chemistry 277 (15), 12960-12969, 2002 | 247 | 2002 |
Cloning and characterization of a novel human alkaline ceramidase: a mammalian enzyme that hydrolyzes phytoceramide C Mao, R Xu, ZM Szulc, A Bielawska, SH Galadari, LM Obeid Journal of Biological Chemistry 276 (28), 26577-26588, 2001 | 197 | 2001 |
Involvement of dihydroceramide desaturase in cell cycle progression in human neuroblastoma cells JM Kraveka, L Li, ZM Szulc, J Bielawski, B Ogretmen, YA Hannun, ... Journal of Biological Chemistry 282 (23), 16718-16728, 2007 | 193 | 2007 |
Cloning and characterization of a Saccharomyces cerevisiae alkaline ceramidase with specificity for dihydroceramide C Mao, R Xu, A Bielawska, ZM Szulc, LM Obeid Journal of Biological Chemistry 275 (40), 31369-31378, 2000 | 187 | 2000 |
The structural requirements for ceramide activation of serine-threonine protein phosphatases CE Chalfant, Z Szulc, P Roddy, A Bielawska, YA Hannun Journal of lipid research 45 (3), 496-506, 2004 | 186 | 2004 |
Lipotoxic very-long-chain ceramides cause mitochondrial dysfunction, oxidative stress, and cell death in cardiomyocytes BA Law, X Liao, KS Moore, A Southard, P Roddy, R Ji, Z Szulc, ... The FASEB Journal 32 (3), 1403, 2018 | 184 | 2018 |
Golgi alkaline ceramidase regulates cell proliferation and survival by controlling levels of sphingosine and S1P R Xu, J Jin, W Hu, W Sun, J Bielawski, Z Szulc, T Taha, LM Obeid, C Mao The FASEB Journal 20 (11), 1813-1825, 2006 | 176 | 2006 |
Comprehensive quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography–tandem mass spectrometry J Bielawski, JS Pierce, J Snider, B Rembiesa, ZM Szulc, A Bielawska Lipidomics: Volume 1: Methods and Protocols, 443-467, 2009 | 170 | 2009 |
Targeting FLT3-ITD signaling mediates ceramide-dependent mitophagy and attenuates drug resistance in AML M Dany, S Gencer, R Nganga, RJ Thomas, N Oleinik, KD Baron, ZM Szulc, ... Blood, The Journal of the American Society of Hematology 128 (15), 1944-1958, 2016 | 169 | 2016 |
Rapid shortening of telomere length in response to ceramide involves the inhibition of telomere binding activity of nuclear glyceraldehyde-3-phosphate dehydrogenase KP Sundararaj, RE Wood, S Ponnusamy, AM Salas, Z Szulc, A Bielawska, ... Journal of Biological Chemistry 279 (7), 6152-6162, 2004 | 158 | 2004 |
Ceramide 1-phosphate acts as a positive allosteric activator of group IVA cytosolic phospholipase A2α and enhances the interaction of the enzyme with phosphatidylcholine P Subramanian, RV Stahelin, Z Szulc, A Bielawska, W Cho, CE Chalfant Journal of Biological Chemistry 280 (18), 17601-17607, 2005 | 152 | 2005 |
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Positively charged ceramide is a potent inducer of mitochondrial permeabilization SA Novgorodov, ZM Szulc, C Luberto, JA Jones, J Bielawski, A Bielawska, ... Journal of Biological Chemistry 280 (16), 16096-16105, 2005 | 123 | 2005 |
Golgi fragmentation is associated with ceramide-induced cellular effects W Hu, R Xu, G Zhang, J Jin, ZM Szulc, J Bielawski, YA Hannun, LM Obeid, ... Molecular biology of the cell 16 (3), 1555-1567, 2005 | 120 | 2005 |
Upregulation of the human alkaline ceramidase 1 and acid ceramidase mediates calcium-induced differentiation of epidermal keratinocytes W Sun, R Xu, W Hu, J Jin, HA Crellin, J Bielawski, ZM Szulc, BH Thiers, ... Journal of Investigative Dermatology 128 (2), 389-397, 2008 | 107 | 2008 |
Substrate specificity of human ceramide kinase DS Wijesinghe, A Massiello, P Subramanian, Z Szulc, A Bielawska, ... Journal of lipid research 46 (12), 2706-2716, 2005 | 104 | 2005 |
Cloning and characterization of a mouse endoplasmic reticulum alkaline ceramidase: an enzyme that preferentially regulates metabolism of very long chain ceramides C Mao, R Xu, ZM Szulc, J Bielawski, KP Becker, A Bielawska, ... Journal of Biological Chemistry 278 (33), 31184-31191, 2003 | 104 | 2003 |