Shear-stress sensitive lenticular vesicles for targeted drug delivery MN Holme, IA Fedotenko, D Abegg, J Althaus, L Babel, F Favarger, ... Nature nanotechnology 7 (8), 536-543, 2012 | 296 | 2012 |
Proteome‐wide profiling of targets of cysteine reactive small molecules by using ethynyl benziodoxolone reagents D Abegg, R Frei, L Cerato, D Prasad Hari, C Wang, J Waser, A Adibekian Angewandte Chemie 127 (37), 11002-11007, 2015 | 163 | 2015 |
Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer MG Costales, H Aikawa, Y Li, JL Childs-Disney, D Abegg, DG Hoch, ... Proceedings of the National Academy of Sciences 117 (5), 2406-2411, 2020 | 134 | 2020 |
Strained cyclic disulfides enable cellular uptake by reacting with the transferrin receptor D Abegg, G Gasparini, DG Hoch, A Shuster, E Bartolami, S Matile, ... Journal of the American Chemical Society 139 (1), 231-238, 2017 | 118 | 2017 |
Translation of the intrinsically disordered protein α-synuclein is inhibited by a small molecule targeting its structured mRNA P Zhang, HJ Park, J Zhang, E Junn, RJ Andrews, SP Velagapudi, ... Proceedings of the National Academy of Sciences 117 (3), 1457-1467, 2020 | 83 | 2020 |
Epidithiodiketopiperazines: Strain-promoted thiol-mediated cellular uptake at the highest tension L Zong, E Bartolami, D Abegg, A Adibekian, N Sakai, S Matile ACS central science 3 (5), 449-453, 2017 | 79 | 2017 |
Cysteine-reactive probes and their use in chemical proteomics DG Hoch, D Abegg, A Adibekian Chemical communications 54 (36), 4501-4512, 2018 | 64 | 2018 |
Reprogramming of protein-targeted small-molecule medicines to RNA by ribonuclease recruitment P Zhang, X Liu, D Abegg, T Tanaka, Y Tong, RI Benhamou, J Baisden, ... Journal of the American Chemical Society 143 (33), 13044-13055, 2021 | 63 | 2021 |
Identification of covalent bromodomain binders through DNA display of small molecules JP Daguer, C Zambaldo, D Abegg, S Barluenga, C Tallant, S Müller, ... Angewandte Chemie International Edition 54 (20), 6057-6061, 2015 | 61 | 2015 |
A designed small molecule inhibitor of a non-coding RNA sensitizes HER2 negative cancers to herceptin MG Costales, DG Hoch, D Abegg, JL Childs-Disney, SP Velagapudi, ... Journal of the American Chemical Society 141 (7), 2960-2974, 2019 | 60 | 2019 |
S100A11/ANXA2 belongs to a tumour suppressor/oncogene network deregulated early with steatosis and involved in inflammation and hepatocellular carcinoma development C Sobolewski, D Abegg, F Berthou, D Dolicka, N Calo, C Sempoux, ... Gut 69 (10), 1841-1854, 2020 | 59 | 2020 |
Ethynylation of cysteine residues: from peptides to proteins in vitro and in living cells R Tessier, RK Nandi, BG Dwyer, D Abegg, C Sornay, J Ceballos, S Erb, ... Angewandte Chemie International Edition 59 (27), 10961-10970, 2020 | 59 | 2020 |
Chemoproteomics‐Enabled Discovery of a Potent and Selective Inhibitor of the DNA Repair Protein MGMT C Wang, D Abegg, DG Hoch, A Adibekian Angewandte Chemie International Edition 55 (8), 2911-2915, 2016 | 54 | 2016 |
Design of a small molecule that stimulates vascular endothelial growth factor A enabled by screening RNA fold–small molecule interactions HS Haniff, L Knerr, X Liu, G Crynen, J Boström, D Abegg, A Adibekian, ... Nature chemistry 12 (10), 952-961, 2020 | 47 | 2020 |
Total Synthesis, Biological Evaluation, and Target Identification of Rare Abies Sesquiterpenoids DC Davis, DG Hoch, L Wu, D Abegg, BS Martin, ZY Zhang, A Adibekian, ... Journal of the American Chemical Society 140 (50), 17465-17473, 2018 | 42 | 2018 |
Divergent synthesis and identification of the cellular targets of deoxyelephantopins R Lagoutte, C Serba, D Abegg, DG Hoch, A Adibekian, N Winssinger Nature communications 7 (1), 1-11, 2016 | 42 | 2016 |
Programming inactive RNA-binding small molecules into bioactive degraders Y Tong, Y Lee, X Liu, JL Childs-Disney, BM Suresh, RI Benhamou, ... Nature 618 (7963), 169-179, 2023 | 37 | 2023 |
DNA-encoded library screening to inform design of a ribonuclease targeting chimera (RiboTAC) SM Meyer, T Tanaka, PRA Zanon, JT Baisden, D Abegg, X Yang, ... Journal of the American Chemical Society 144 (46), 21096-21102, 2022 | 30 | 2022 |
DNA-encoded library versus RNA-encoded library selection enables design of an oncogenic noncoding RNA inhibitor RI Benhamou, BM Suresh, Y Tong, WG Cochrane, V Cavett, ... Proceedings of the National Academy of Sciences 119 (6), e2114971119, 2022 | 30 | 2022 |
Chemoproteomic profiling by cysteine fluoroalkylation reveals myrocin G as an inhibitor of the nonhomologous end joining DNA repair pathway D Abegg, M Tomanik, N Qiu, D Pechalrieu, A Shuster, B Commare, ... Journal of the American Chemical Society 143 (48), 20332-20342, 2021 | 30 | 2021 |