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Daniel Abegg
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Shear-stress sensitive lenticular vesicles for targeted drug delivery
MN Holme, IA Fedotenko, D Abegg, J Althaus, L Babel, F Favarger, ...
Nature nanotechnology 7 (8), 536-543, 2012
2962012
Proteome‐wide profiling of targets of cysteine reactive small molecules by using ethynyl benziodoxolone reagents
D Abegg, R Frei, L Cerato, D Prasad Hari, C Wang, J Waser, A Adibekian
Angewandte Chemie 127 (37), 11002-11007, 2015
1632015
Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer
MG Costales, H Aikawa, Y Li, JL Childs-Disney, D Abegg, DG Hoch, ...
Proceedings of the National Academy of Sciences 117 (5), 2406-2411, 2020
1342020
Strained cyclic disulfides enable cellular uptake by reacting with the transferrin receptor
D Abegg, G Gasparini, DG Hoch, A Shuster, E Bartolami, S Matile, ...
Journal of the American Chemical Society 139 (1), 231-238, 2017
1182017
Translation of the intrinsically disordered protein α-synuclein is inhibited by a small molecule targeting its structured mRNA
P Zhang, HJ Park, J Zhang, E Junn, RJ Andrews, SP Velagapudi, ...
Proceedings of the National Academy of Sciences 117 (3), 1457-1467, 2020
832020
Epidithiodiketopiperazines: Strain-promoted thiol-mediated cellular uptake at the highest tension
L Zong, E Bartolami, D Abegg, A Adibekian, N Sakai, S Matile
ACS central science 3 (5), 449-453, 2017
792017
Cysteine-reactive probes and their use in chemical proteomics
DG Hoch, D Abegg, A Adibekian
Chemical communications 54 (36), 4501-4512, 2018
642018
Reprogramming of protein-targeted small-molecule medicines to RNA by ribonuclease recruitment
P Zhang, X Liu, D Abegg, T Tanaka, Y Tong, RI Benhamou, J Baisden, ...
Journal of the American Chemical Society 143 (33), 13044-13055, 2021
632021
Identification of covalent bromodomain binders through DNA display of small molecules
JP Daguer, C Zambaldo, D Abegg, S Barluenga, C Tallant, S Müller, ...
Angewandte Chemie International Edition 54 (20), 6057-6061, 2015
612015
A designed small molecule inhibitor of a non-coding RNA sensitizes HER2 negative cancers to herceptin
MG Costales, DG Hoch, D Abegg, JL Childs-Disney, SP Velagapudi, ...
Journal of the American Chemical Society 141 (7), 2960-2974, 2019
602019
S100A11/ANXA2 belongs to a tumour suppressor/oncogene network deregulated early with steatosis and involved in inflammation and hepatocellular carcinoma development
C Sobolewski, D Abegg, F Berthou, D Dolicka, N Calo, C Sempoux, ...
Gut 69 (10), 1841-1854, 2020
592020
Ethynylation of cysteine residues: from peptides to proteins in vitro and in living cells
R Tessier, RK Nandi, BG Dwyer, D Abegg, C Sornay, J Ceballos, S Erb, ...
Angewandte Chemie International Edition 59 (27), 10961-10970, 2020
592020
Chemoproteomics‐Enabled Discovery of a Potent and Selective Inhibitor of the DNA Repair Protein MGMT
C Wang, D Abegg, DG Hoch, A Adibekian
Angewandte Chemie International Edition 55 (8), 2911-2915, 2016
542016
Design of a small molecule that stimulates vascular endothelial growth factor A enabled by screening RNA fold–small molecule interactions
HS Haniff, L Knerr, X Liu, G Crynen, J Boström, D Abegg, A Adibekian, ...
Nature chemistry 12 (10), 952-961, 2020
472020
Total Synthesis, Biological Evaluation, and Target Identification of Rare Abies Sesquiterpenoids
DC Davis, DG Hoch, L Wu, D Abegg, BS Martin, ZY Zhang, A Adibekian, ...
Journal of the American Chemical Society 140 (50), 17465-17473, 2018
422018
Divergent synthesis and identification of the cellular targets of deoxyelephantopins
R Lagoutte, C Serba, D Abegg, DG Hoch, A Adibekian, N Winssinger
Nature communications 7 (1), 1-11, 2016
422016
Programming inactive RNA-binding small molecules into bioactive degraders
Y Tong, Y Lee, X Liu, JL Childs-Disney, BM Suresh, RI Benhamou, ...
Nature 618 (7963), 169-179, 2023
372023
DNA-encoded library screening to inform design of a ribonuclease targeting chimera (RiboTAC)
SM Meyer, T Tanaka, PRA Zanon, JT Baisden, D Abegg, X Yang, ...
Journal of the American Chemical Society 144 (46), 21096-21102, 2022
302022
DNA-encoded library versus RNA-encoded library selection enables design of an oncogenic noncoding RNA inhibitor
RI Benhamou, BM Suresh, Y Tong, WG Cochrane, V Cavett, ...
Proceedings of the National Academy of Sciences 119 (6), e2114971119, 2022
302022
Chemoproteomic profiling by cysteine fluoroalkylation reveals myrocin G as an inhibitor of the nonhomologous end joining DNA repair pathway
D Abegg, M Tomanik, N Qiu, D Pechalrieu, A Shuster, B Commare, ...
Journal of the American Chemical Society 143 (48), 20332-20342, 2021
302021
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