Analysis of gene expression in two large schizophrenia cohorts identifies multiple changes associated with nerve terminal function PR Maycox, F Kelly, A Taylor, S Bates, J Reid, R Logendra, MR Barnes, ... Molecular psychiatry 14 (12), 1083-1094, 2009 | 227 | 2009 |
The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis HV Woodcock, JD Eley, D Guillotin, M Platé, CB Nanthakumar, M Martufi, ... Nature communications 10 (1), 6, 2019 | 167 | 2019 |
mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-β1–induced collagen biosynthesis B Selvarajah, I Azuelos, M Platé, D Guillotin, EJ Forty, G Contento, ... Science signaling 12 (582), eaav3048, 2019 | 139 | 2019 |
Transcription and pathway analysis of the superior temporal cortex and anterior prefrontal cortex in schizophrenia MR Barnes, J Huxley‐Jones, PR Maycox, M Lennon, A Thornber, F Kelly, ... Journal of neuroscience research 89 (8), 1218-1227, 2011 | 98 | 2011 |
Treatment with an antibody directed against Nogo-A delays disease progression in the SOD1G93A mouse model of Amyotrophic lateral sclerosis V Bros-Facer, D Krull, A Taylor, JRT Dick, SA Bates, MS Cleveland, ... Human molecular genetics 23 (16), 4187-4200, 2014 | 53 | 2014 |
Increased expression of the NR2A NMDA receptor subunit in the prefrontal cortex of rats reared in isolation JJ Turnock‐Jones, CA Jennings, MJ Robbins, JE Cluderay, J Cilia, ... Synapse 63 (10), 836-846, 2009 | 52 | 2009 |
Expression profiling of a genetic animal model of depression reveals novel molecular pathways underlying depressive-like behaviours E Blaveri, F Kelly, A Mallei, K Harris, A Taylor, J Reid, M Razzoli, ... PloS one 5 (9), e12596, 2010 | 51 | 2010 |
Blood eosinophil count and airway epithelial transcriptome relationships in COPD versus asthma L George, AR Taylor, A Esteve‐Codina, M Soler Artigas, GA Thun, ... Allergy 75 (2), 370-380, 2020 | 48 | 2020 |
Safety, tolerability, pharmacokinetics, and pharmacodynamics of single-dose antiinterleukin-18 mAb GSK1070806 in healthy and obese subjects. P Mistry, J Reid, I Pouliquen, S McHugh, L Abberley, S DeWall, A Taylor, ... International journal of clinical pharmacology and therapeutics 52 (10), 867-879, 2014 | 39 | 2014 |
Kernel methods for predicting yields of chemical reactions AL Haywood, J Redshaw, MWD Hanson-Heine, A Taylor, A Brown, ... Journal of Chemical Information and Modeling 62 (9), 2077-2092, 2021 | 37 | 2021 |
Transcriptome analysis of IPF fibroblastic foci identifies key pathways involved in fibrogenesis D Guillotin, AR Taylor, M Platé, PF Mercer, LM Edwards, R Haggart, ... Thorax 76 (1), 73-82, 2021 | 36 | 2021 |
Molecular basis for clinical diversity between autoantibody subsets in diffuse cutaneous systemic sclerosis KEN Clark, C Campochiaro, E Csomor, A Taylor, K Nevin, N Galwey, ... Annals of the Rheumatic Diseases 80 (12), 1584-1593, 2021 | 28 | 2021 |
Modeling bispecific monoclonal antibody interaction with two cell membrane targets indicates the importance of surface diffusion BG Sengers, S McGinty, FZ Nouri, M Argungu, E Hawkins, A Hadji, ... MAbs 8 (5), 905-915, 2016 | 25 | 2016 |
Transforming growth factor beta gene signatures are spatially enriched in keloid tissue biopsies and ex vivo-cultured keloid fibroblasts A Taylor, DC Budd, B Shih, O Seifert, A Beaton, T Wright, M Dempsey, ... Acta dermato-venereologica 97 (1), 10-16, 2017 | 23 | 2017 |
Cluster analysis of transcriptomic datasets to identify endotypes of idiopathic pulmonary fibrosis LM Kraven, AR Taylor, PL Molyneaux, TM Maher, JE McDonough, ... Thorax 78 (6), 551-558, 2023 | 18 | 2023 |
IL1RAP expression and the enrichment of IL‐33 activation signatures in severe neutrophilic asthma YE Badi, B Salcman, A Taylor, B Rana, NZ Kermani, JH Riley, S Worsley, ... Allergy 78 (1), 156-167, 2023 | 16 | 2023 |
Machine Learning for Chemical Synthesis AL Haywood, J Redshaw, T Gaertner, A Taylor, AM Mason, JD Hirst | 5 | 2020 |
Topological data analysis (TDA) of U-BIOPRED paediatric peripheral blood gene expression identified asthma phenotypes characterised by alternative splicing of glucocorticoid … JPR Schofield, J Bigler, M Boedigheimer, K Affleck, A Taylor, S Pavlidis, ... European Respiratory Journal 52 (suppl 62), 2018 | 2 | 2018 |
Weighted Gene Co-expression Network Analysis of blood paediatric samples from the U-BIOPRED study identifies oxidative stress association with asthma severity S Pavlidis, Y Guo, K Sun, B de Meulder, J Riley, K Affleck, A Taylor, ... European Respiratory Journal 52 (suppl 62), 2018 | 1 | 2018 |
Machine Learning for Chemical Synthesis AL Haywood, J Redshaw, T Gärtner, A Taylor, AM Mason, JD Hirst # PLACEHOLDER_PARENT_METADATA_VALUE#, 169-194, 2020 | | 2020 |