Aldose reductase–mediated phosphorylation of p53 leads to mitochondrial dysfunction and damage in diabetic platelets WH Tang, J Stitham, Y Jin, R Liu, SH Lee, J Du, G Atteya, S Gleim, ... Circulation 129 (15), 1598-1609, 2014 | 113 | 2014 |
Inducing mitophagy in diabetic platelets protects against severe oxidative stress SH Lee, J Du, J Stitham, G Atteya, S Lee, Y Xiang, D Wang, Y Jin, ... EMBO Molecular Medicine 8 (7), 779-795, 2016 | 106 | 2016 |
Hyperglycemia repression of miR-24 coordinately upregulates endothelial cell expression and secretion of von Willebrand factor Y Xiang, J Cheng, D Wang, X Hu, Y Xie, J Stitham, G Atteya, J Du, ... Blood, The Journal of the American Society of Hematology 125 (22), 3377-3387, 2015 | 101 | 2015 |
Characterization of Heme Ligation Properties of Rv0203, a Secreted Heme Binding Protein Involved in Mycobacterium tuberculosis Heme Uptake CP Owens, J Du, JH Dawson, CW Goulding Biochemistry 51 (7), 1518-1531, 2012 | 87 | 2012 |
The H93G myoglobin cavity mutant as a versatile scaffold for modeling heme iron coordination structures in protein active sites and their characterization with magnetic … J Du, M Sono, JH Dawson Coordination chemistry reviews 255 (7-8), 700-716, 2011 | 61 | 2011 |
Mitochondrial MsrB2 serves as a switch and transducer for mitophagy SH Lee, S Lee, J Du, K Jain, M Ding, AJ Kadado, G Atteya, Z Jaji, T Tyagi, ... EMBO molecular medicine 11 (8), e10409, 2019 | 53 | 2019 |
Probing the Oxyferrous and Catalytically Active Ferryl States of Amphitrite ornata Dehaloperoxidase by Cryoreduction and EPR/ENDOR Spectroscopy. Detection of … R Davydov, RL Osborne, M Shanmugam, J Du, JH Dawson, BM Hoffman Journal of the American Chemical Society 132 (42), 14995-15004, 2010 | 52 | 2010 |
Heme binding to the mammalian circadian clock protein period 2 is nonspecific MV Airola, J Du, JH Dawson, BR Crane Biochemistry 49 (20), 4327-4338, 2010 | 52 | 2010 |
Investigations of heme ligation and ligand switching in cytochromes P450 and P420 Y Sun, W Zeng, A Benabbas, X Ye, I Denisov, SG Sligar, J Du, ... Biochemistry 52 (34), 5941-5951, 2013 | 50 | 2013 |
Functional Switching of Amphitrite ornata Dehaloperoxidase from O2-Binding Globin to Peroxidase Enzyme Facilitated by Halophenol Substrate and H2O2 J Du, M Sono, JH Dawson Biochemistry 49 (29), 6064-6069, 2010 | 50 | 2010 |
Amphitrite ornata Dehaloperoxidase (DHP): Investigations of Structural Factors That Influence the Mechanism of Halophenol Dehalogenation Using “Peroxidase … J Du, X Huang, S Sun, C Wang, L Lebioda, JH Dawson Biochemistry 50 (38), 8172-8180, 2011 | 46 | 2011 |
Diabetes exacerbates myocardial ischemia/reperfusion injury by down-regulation of microRNA and up-regulation of O-GlcNAcylation D Wang, X Hu, SH Lee, F Chen, K Jiang, Z Tu, Z Liu, J Du, L Wang, C Yin, ... JACC: Basic to Translational Science 3 (3), 350-362, 2018 | 45 | 2018 |
Age associated non-linear regulation of redox homeostasis in the anucleate platelet: Implications for CVD risk patients K Jain, T Tyagi, K Patell, Y Xie, AJ Kadado, SH Lee, T Yarovinsky, J Du, ... EBioMedicine 44, 28-40, 2019 | 38 | 2019 |
Influence of heme environment structure on dioxygen affinity for the dual function Amphitrite ornata hemoglobin/dehaloperoxidase. Insights into the evolutional structure … S Sun, M Sono, C Wang, J Du, L Lebioda, JH Dawson Archives of biochemistry and biophysics 545, 108-115, 2014 | 26 | 2014 |
Opposing actions of AKT (protein kinase B) isoforms in vascular smooth muscle injury and therapeutic response Y Jin, Y Xie, AC Ostriker, X Zhang, R Liu, MY Lee, KL Leslie, W Tang, ... Arteriosclerosis, thrombosis, and vascular biology 37 (12), 2311-2321, 2017 | 25 | 2017 |
A Novel Intermediate in the Reaction of Seleno CYP119 with m-Chloroperbenzoic Acid S Sivaramakrishnan, H Ouellet, J Du, KJ McLean, KF Medzihradszky, ... Biochemistry 50 (14), 3014-3024, 2011 | 23 | 2011 |
Enterococcus faecalis 6-phosphogluconolactonase is required for both commensal and pathogenic interactions with Manduca sexta JF Holt, MR Kiedrowski, KL Frank, J Du, C Guan, NA Broderick, ... Infection and immunity 83 (1), 396-404, 2015 | 22 | 2015 |
Alkylamine-ligated H93G myoglobin cavity mutant: a model system for endogenous lysine and terminal amine ligation in heme proteins such as nitrite reductase and cytochrome f J Du, R Perera, JH Dawson Inorganic chemistry 50 (4), 1242-1249, 2011 | 22 | 2011 |
Platelet-derived TLT-1 promotes tumor progression by suppressing CD8+ T cells T Tyagi, K Jain, TO Yarovinsky, M Chiorazzi, J Du, C Castro, J Griffin, ... Journal of Experimental Medicine 220 (1), e20212218, 2022 | 20 | 2022 |
Evidence of the Direct Involvement of the Substrate TCP Radical in Functional Switching from Oxyferrous O2 Carrier to Ferric Peroxidase in the Dual-Function Hemoglobin … S Sun, M Sono, J Du, JH Dawson Biochemistry 53 (30), 4956-4969, 2014 | 16 | 2014 |