RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome L Duprez, N Takahashi, F Van Hauwermeiren, B Vandendriessche, ... Immunity 35 (6), 908-918, 2011 | 597 | 2011 |
Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models N Takahashi, L Duprez, S Grootjans, A Cauwels, W Nerinckx, ... Cell death & disease 3 (11), e437-e437, 2012 | 489 | 2012 |
New insights into the anti-inflammatory mechanisms of glucocorticoids: an emerging role for glucocorticoid-receptor-mediated transactivation S Vandevyver, L Dejager, J Tuckermann, C Libert Endocrinology 154 (3), 993-1007, 2013 | 337 | 2013 |
Extracellular ATP drives systemic inflammation, tissue damage and mortality A Cauwels, E Rogge, B Vandendriessche, S Shiva, P Brouckaert Cell death & disease 5 (3), e1102-e1102, 2014 | 279 | 2014 |
Caspase inhibition causes hyperacute tumor necrosis factor–induced shock via oxidative stress and phospholipase A2 A Cauwels, B Janssen, A Waeytens, C Cuvelier, P Brouckaert Nature immunology 4 (4), 387-393, 2003 | 276 | 2003 |
IL-17 produced by Paneth cells drives TNF-induced shock N Takahashi, I Vanlaere, R De Rycke, A Cauwels, LAB Joosten, ... The Journal of experimental medicine 205 (8), 1755-1761, 2008 | 221 | 2008 |
Nitric oxide in shock A Cauwels Kidney international 72 (5), 557-565, 2007 | 215 | 2007 |
Simultaneous targeting of IL-1 and IL-18 is required for protection against inflammatory and septic shock TV Berghe, D Demon, P Bogaert, B Vandendriessche, A Goethals, ... American journal of respiratory and critical care medicine 189 (3), 282-291, 2014 | 181 | 2014 |
Acute injury in the peripheral nervous system triggers an alternative macrophage response E Ydens, A Cauwels, B Asselbergh, S Goethals, L Peeraer, G Lornet, ... Journal of neuroinflammation 9, 1-17, 2012 | 174 | 2012 |
Anaphylactic shock depends on PI3K and eNOS-derived NO A Cauwels, B Janssen, E Buys, P Sips, P Brouckaert The Journal of clinical investigation 116 (8), 2244-2251, 2006 | 161 | 2006 |
Tumor necrosis factor, its receptors and the connection with interleukin 1 and interleukin 6 P Brouckaert, C Libert, B Everaerdt, N Takahashi, A Cauwels, W Fiers Immunobiology 187 (3-5), 317-329, 1993 | 160 | 1993 |
TLR-2 and TLR-9 are sensors of apoptosis in a mouse model of doxorubicin-induced acute inflammation DV Krysko, A Kaczmarek, O Krysko, L Heyndrickx, J Woznicki, P Bogaert, ... Cell Death & Differentiation 18 (8), 1316-1325, 2011 | 135 | 2011 |
The origin and function of soluble CD14 in experimental bacterial meningitis A Cauwels, K Frei, S Sansano, C Fearns, R Ulevitch, W Zimmerli, ... The Journal of Immunology 162 (8), 4762-4772, 1999 | 106 | 1999 |
Identification of a Streptococcus pneumoniae Gene Locus Encoding Proteins of an ABC Phosphate Transporter and a Two-Component Regulatory System R Novak, A Cauwels, E Charpentier, E Tuomanen Journal of bacteriology 181 (4), 1126-1133, 1999 | 96 | 1999 |
Nitrite protects against morbidity and mortality associated with TNF-or LPS-induced shock in a soluble guanylate cyclase–dependent manner A Cauwels, ES Buys, R Thoonen, L Geary, J Delanghe, S Shiva, ... Journal of Experimental Medicine 206 (13), 2915-2924, 2009 | 94 | 2009 |
Systemic NO production during (septic) shock depends on parenchymal and not on hematopoietic cells: in vivo iNOS expression pattern in (septic) shock J Bultinck, P Sips, L Vakaet, P Brouckaert, A Cauwels, J Bultinck, P Sips, ... The FASEB journal 20 (13), 2363-2365, 2006 | 90 | 2006 |
Response of interleukin‐6‐deficient mice to tumor necrosis factor‐induced metabolic changes and lethality C Libert, N Takahashi, A Cauwels, P Brouckaert, H Bluethmann, W Fiers European Journal of Immunology 24 (9), 2237-2242, 1994 | 89 | 1994 |
Delivering type I interferon to dendritic cells empowers tumor eradication and immune combination treatments A Cauwels, S Van Lint, F Paul, G Garcin, S De Koker, A Van Parys, ... Cancer research 78 (2), 463-474, 2018 | 87 | 2018 |
Cardiovascular and pharmacological implications of haem-deficient NO-unresponsive soluble guanylate cyclase knock-in mice R Thoonen, A Cauwels, K Decaluwe, S Geschka, RE Tainsh, J Delanghe, ... Nature communications 6 (1), 8482, 2015 | 85 | 2015 |
Coexistence of CD14-dependent and independent pathways for stimulation of human monocytes by gram-positive bacteria A Cauwels, E Wan, M Leismann, E Tuomanen Infection and immunity 65 (8), 3255-3260, 1997 | 82 | 1997 |