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Zara Molphy
Zara Molphy
Postdoctoral researcher, Dublin City University
在 mail.dcu.ie 的电子邮件经过验证 - 首页
标题
引用次数
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年份
Molecular methods for assessment of non-covalent metallodrug–DNA interactions
A Kellett, Z Molphy, C Slator, V McKee, NP Farrell
Chemical Society Reviews 48 (4), 971-988, 2019
2532019
Copper phenanthrene oxidative chemical nucleases
Z Molphy, A Prisecaru, C Slator, N Barron, M McCann, J Colleran, ...
Inorganic chemistry 53 (10), 5392-5404, 2014
1062014
DNA oxidation profiles of copper phenanthrene chemical nucleases
Z Molphy, C Slator, C Chatgilialoglu, A Kellett
Frontiers in Chemistry 3, 28, 2015
622015
Di-copper metallodrugs promote NCI-60 chemotherapy via singlet oxygen and superoxide production with tandem TA/TA and AT/AT oligonucleotide discrimination
C Slator, Z Molphy, V McKee, C Long, T Brown, A Kellett
Nucleic Acids Research 46 (6), 2733-2750, 2018
602018
The phosphate clamp: sequence selective nucleic acid binding profiles and conformational induction of endonuclease inhibition by cationic Triplatin complexes
A Prisecaru, Z Molphy, RG Kipping, EJ Peterson, Y Qu, A Kellett, ...
Nucleic acids research 42 (22), 13474-13487, 2014
512014
A phosphate-targeted dinuclear Cu (II) complex combining major groove binding and oxidative DNA cleavage
Z Molphy, D Montagner, SS Bhat, C Slator, C Long, A Erxleben, A Kellett
Nucleic Acids Research 46 (19), 9918-9931, 2018
502018
Polypyridyl‐Based Copper Phenanthrene Complexes: A New Type of Stabilized Artificial Chemical Nuclease
N Zuin Fantoni, Z Molphy, C Slator, G Menounou, G Toniolo, G Mitrikas, ...
Chemistry–A European Journal 25 (1), 221-237, 2019
372019
Recent advances in anticancer copper compounds
A Kellett, Z Molphy, V McKee, C Slator
362019
Cu(ii) phenanthroline–phenazine complexes dysregulate mitochondrial function and stimulate apoptosis
G Rochford, Z Molphy, K Kavanagh, M McCann, M Devereux, A Kellett, ...
Metallomics 12 (1), 65-78, 2020
342020
Triggering autophagic cell death with a di-manganese (II) developmental therapeutic
C Slator, Z Molphy, V McKee, A Kellett
Redox biology 12, 150-161, 2017
332017
Exploring the DNA binding, oxidative cleavage, and cytotoxic properties of new ternary copper (II) compounds containing 4-aminoantipyrine and N, N-heterocyclic co-ligands
IP de Souza, BP Machado, AB de Carvalho, I Binatti, K Krambrock, ...
Journal of Molecular Structure 1178, 18-28, 2019
252019
Polypyridyl‐based copper phenanthrene complexes: combining stability with enhanced DNA recognition
NZ Fantoni, Z Molphy, S O'Carroll, G Menounou, G Mitrikas, MG Krokidis, ...
Chemistry–A European Journal 27 (3), 971-983, 2021
202021
A Click Chemistry Approach to Targeted DNA Crosslinking with cis‐Platinum(II)‐Modified Triplex‐Forming Oligonucleotides
J Hennessy, B McGorman, Z Molphy, NP Farrell, D Singleton, T Brown, ...
Angewandte Chemie 134 (3), e202110455, 2022
182022
Copper (II) and silver (I)-1, 10-phenanthroline-5, 6-dione complexes interact with double-stranded DNA: Further evidence of their apparent multi-modal activity towards …
ACM Galdino, L Viganor, MM Pereira, M Devereux, M McCann, ...
JBIC Journal of Biological Inorganic Chemistry 27 (1), 201-213, 2022
172022
Development of Gene‐Targeted Polypyridyl Triplex‐Forming Oligonucleotide Hybrids
N Zuin Fantoni, B McGorman, Z Molphy, D Singleton, S Walsh, ...
ChemBioChem 21 (24), 3563-3574, 2020
172020
Radical-induced purine lesion formation is dependent on DNA helical topology
MA Terzidis, A Prisecaru, Z Molphy, N Barron, A Randazzo, E Dumont, ...
Free Radical Research 50 (sup1), S91-S101, 2016
162016
In-vivo evaluation of the response of Galleria mellonella larvae to novel copper (II) phenanthroline-phenazine complexes
G Rochford, Z Molphy, N Browne, C Surlis, M Devereux, M McCann, ...
Journal of Inorganic Biochemistry 186, 135-146, 2018
132018
C 3-symmetric opioid scaffolds are pH-responsive DNA condensation agents
N McStay, Z Molphy, A Coughlan, A Cafolla, V McKee, N Gathergood, ...
Nucleic Acids Research 45 (2), 527-540, 2017
132017
Assessment of DNA topoisomerase I unwinding activity, radical scavenging capacity, and inhibition of breast cancer cell viability of N-alkyl-acridones and N, N′-dialkyl-9, 9 …
MG Krokidis, Z Molphy, EK Efthimiadou, M Kokoli, SM Argyri, I Dousi, ...
Biomolecules 9 (5), 177, 2019
102019
Metal-bases anticancer agents
A Kellett, Z Molphy, V McKee, C Slator, A Casini, A Vessières, ...
Royal Society of Chemistry,, 2019
92019
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