Molecular methods for assessment of non-covalent metallodrug–DNA interactions A Kellett, Z Molphy, C Slator, V McKee, NP Farrell Chemical Society Reviews 48 (4), 971-988, 2019 | 253 | 2019 |
Copper phenanthrene oxidative chemical nucleases Z Molphy, A Prisecaru, C Slator, N Barron, M McCann, J Colleran, ... Inorganic chemistry 53 (10), 5392-5404, 2014 | 106 | 2014 |
DNA oxidation profiles of copper phenanthrene chemical nucleases Z Molphy, C Slator, C Chatgilialoglu, A Kellett Frontiers in Chemistry 3, 28, 2015 | 62 | 2015 |
Di-copper metallodrugs promote NCI-60 chemotherapy via singlet oxygen and superoxide production with tandem TA/TA and AT/AT oligonucleotide discrimination C Slator, Z Molphy, V McKee, C Long, T Brown, A Kellett Nucleic Acids Research 46 (6), 2733-2750, 2018 | 60 | 2018 |
The phosphate clamp: sequence selective nucleic acid binding profiles and conformational induction of endonuclease inhibition by cationic Triplatin complexes A Prisecaru, Z Molphy, RG Kipping, EJ Peterson, Y Qu, A Kellett, ... Nucleic acids research 42 (22), 13474-13487, 2014 | 51 | 2014 |
A phosphate-targeted dinuclear Cu (II) complex combining major groove binding and oxidative DNA cleavage Z Molphy, D Montagner, SS Bhat, C Slator, C Long, A Erxleben, A Kellett Nucleic Acids Research 46 (19), 9918-9931, 2018 | 50 | 2018 |
Polypyridyl‐Based Copper Phenanthrene Complexes: A New Type of Stabilized Artificial Chemical Nuclease N Zuin Fantoni, Z Molphy, C Slator, G Menounou, G Toniolo, G Mitrikas, ... Chemistry–A European Journal 25 (1), 221-237, 2019 | 37 | 2019 |
Recent advances in anticancer copper compounds A Kellett, Z Molphy, V McKee, C Slator | 36 | 2019 |
Cu(ii) phenanthroline–phenazine complexes dysregulate mitochondrial function and stimulate apoptosis G Rochford, Z Molphy, K Kavanagh, M McCann, M Devereux, A Kellett, ... Metallomics 12 (1), 65-78, 2020 | 34 | 2020 |
Triggering autophagic cell death with a di-manganese (II) developmental therapeutic C Slator, Z Molphy, V McKee, A Kellett Redox biology 12, 150-161, 2017 | 33 | 2017 |
Exploring the DNA binding, oxidative cleavage, and cytotoxic properties of new ternary copper (II) compounds containing 4-aminoantipyrine and N, N-heterocyclic co-ligands IP de Souza, BP Machado, AB de Carvalho, I Binatti, K Krambrock, ... Journal of Molecular Structure 1178, 18-28, 2019 | 25 | 2019 |
Polypyridyl‐based copper phenanthrene complexes: combining stability with enhanced DNA recognition NZ Fantoni, Z Molphy, S O'Carroll, G Menounou, G Mitrikas, MG Krokidis, ... Chemistry–A European Journal 27 (3), 971-983, 2021 | 20 | 2021 |
A Click Chemistry Approach to Targeted DNA Crosslinking with cis‐Platinum(II)‐Modified Triplex‐Forming Oligonucleotides J Hennessy, B McGorman, Z Molphy, NP Farrell, D Singleton, T Brown, ... Angewandte Chemie 134 (3), e202110455, 2022 | 18 | 2022 |
Copper (II) and silver (I)-1, 10-phenanthroline-5, 6-dione complexes interact with double-stranded DNA: Further evidence of their apparent multi-modal activity towards … ACM Galdino, L Viganor, MM Pereira, M Devereux, M McCann, ... JBIC Journal of Biological Inorganic Chemistry 27 (1), 201-213, 2022 | 17 | 2022 |
Development of Gene‐Targeted Polypyridyl Triplex‐Forming Oligonucleotide Hybrids N Zuin Fantoni, B McGorman, Z Molphy, D Singleton, S Walsh, ... ChemBioChem 21 (24), 3563-3574, 2020 | 17 | 2020 |
Radical-induced purine lesion formation is dependent on DNA helical topology MA Terzidis, A Prisecaru, Z Molphy, N Barron, A Randazzo, E Dumont, ... Free Radical Research 50 (sup1), S91-S101, 2016 | 16 | 2016 |
In-vivo evaluation of the response of Galleria mellonella larvae to novel copper (II) phenanthroline-phenazine complexes G Rochford, Z Molphy, N Browne, C Surlis, M Devereux, M McCann, ... Journal of Inorganic Biochemistry 186, 135-146, 2018 | 13 | 2018 |
C 3-symmetric opioid scaffolds are pH-responsive DNA condensation agents N McStay, Z Molphy, A Coughlan, A Cafolla, V McKee, N Gathergood, ... Nucleic Acids Research 45 (2), 527-540, 2017 | 13 | 2017 |
Assessment of DNA topoisomerase I unwinding activity, radical scavenging capacity, and inhibition of breast cancer cell viability of N-alkyl-acridones and N, N′-dialkyl-9, 9 … MG Krokidis, Z Molphy, EK Efthimiadou, M Kokoli, SM Argyri, I Dousi, ... Biomolecules 9 (5), 177, 2019 | 10 | 2019 |
Metal-bases anticancer agents A Kellett, Z Molphy, V McKee, C Slator, A Casini, A Vessières, ... Royal Society of Chemistry,, 2019 | 9 | 2019 |