Twists, knots, and rings in proteins: structural definition of the cyclotide framework KJ Rosengren, NL Daly, MR Plan, C Waine, DJ Craik Journal of Biological Chemistry 278 (10), 8606-8616, 2003 | 379 | 2003 |
Microcin J25 has a threaded sidechain-to-backbone ring structure and not a head-to-tail cyclized backbone KJ Rosengren, RJ Clark, NL Daly, U Göransson, A Jones, DJ Craik Journal of the American Chemical Society 125 (41), 12464-12474, 2003 | 294 | 2003 |
Engineering stable peptide toxins by means of backbone cyclization: stabilization of the α-conotoxin MII RJ Clark, H Fischer, L Dempster, NL Daly, KJ Rosengren, ST Nevin, ... Proceedings of the National Academy of Sciences 102 (39), 13767-13772, 2005 | 290 | 2005 |
Isolation, Solution Structure, and Insecticidal Activity of Kalata B2, a Circular Protein with a Twist: Do Möbius Strips Exist in Nature?, CV Jennings, KJ Rosengren, NL Daly, M Plan, J Stevens, MJ Scanlon, ... Biochemistry 44 (3), 851-860, 2005 | 284 | 2005 |
Solution structures by 1H NMR of the novel cyclic trypsin inhibitor SFTI-1 from sunflower seeds and an acyclic permutant MLJ Korsinczky, HJ Schirra, KJ Rosengren, J West, BA Condie, L Otvos, ... Journal of molecular biology 311 (3), 579-591, 2001 | 270 | 2001 |
Discovery, structure and biological activities of cyclotides NL Daly, KJ Rosengren, DJ Craik Advanced drug delivery reviews 61 (11), 918-930, 2009 | 230 | 2009 |
Alanine scanning mutagenesis of the prototypic cyclotide reveals a cluster of residues essential for bioactivity SM Simonsen, L Sando, KJ Rosengren, CK Wang, ML Colgrave, NL Daly, ... Journal of biological chemistry 283 (15), 9805-9813, 2008 | 200 | 2008 |
Decoding the membrane activity of the cyclotide kalata B1: the importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities ST Henriques, YH Huang, KJ Rosengren, HG Franquelim, FA Carvalho, ... Journal of Biological Chemistry 286 (27), 24231-24241, 2011 | 191 | 2011 |
Theoretical and computational strategies for rational molecularly imprinted polymer design IA Nicholls, HS Andersson, C Charlton, H Henschel, BCG Karlsson, ... Biosensors and Bioelectronics 25 (3), 543-552, 2009 | 191 | 2009 |
Isolation and characterization of novel cyclotides from Viola hederaceae: solution structure and anti-HIV activity of vhl-1, a leaf-specific expressed cyclotide B Chen, ML Colgrave, NL Daly, KJ Rosengren, KR Gustafson, DJ Craik Journal of Biological Chemistry 280 (23), 22395-22405, 2005 | 165 | 2005 |
Identification of crucial residues for the antibacterial activity of the proline‐rich peptide, pyrrhocoricin G Kragol, R Hoffmann, MA Chattergoon, S Lovas, M Cudic, P Bulet, ... European journal of biochemistry 269 (17), 4226-4237, 2002 | 163 | 2002 |
Functional analysis of the α-defensin disulfide array in mouse cryptdin-4 A Maemoto, X Qu, KJ Rosengren, H Tanabe, A Henschen-Edman, ... Journal of Biological Chemistry 279 (42), 44188-44196, 2004 | 157 | 2004 |
Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a JR Deuis, Z Dekan, JS Wingerd, JJ Smith, NR Munasinghe, RF Bhola, ... Scientific reports 7 (1), 40883, 2017 | 145 | 2017 |
Combined X-ray and NMR analysis of the stability of the cyclotide cystine knot fold that underpins its insecticidal activity and potential use as a drug scaffold CK Wang, SH Hu, JL Martin, T Sjogren, J Hajdu, L Bohlin, P Claeson, ... Journal of Biological Chemistry 284 (16), 10672-10683, 2009 | 130 | 2009 |
The A-chain of human relaxin family peptides has distinct roles in the binding and activation of the different relaxin family peptide receptors MA Hossain, KJ Rosengren, LM Haugaard-Jonsson, S Zhang, S Layfield, ... Journal of biological chemistry 283 (25), 17287-17297, 2008 | 114 | 2008 |
Solution structure and novel insights into the determinants of the receptor specificity of human relaxin-3 KJ Rosengren, F Lin, RAD Bathgate, GW Tregear, NL Daly, JD Wade, ... Journal of Biological Chemistry 281 (9), 5845-5851, 2006 | 107 | 2006 |
Semienzymatic cyclization of disulfide-rich peptides using Sortase A X Jia, S Kwon, CIA Wang, YH Huang, LY Chan, CC Tan, KJ Rosengren, ... Journal of biological chemistry 289 (10), 6627-6638, 2014 | 100 | 2014 |
Relaxin-3/RXFP3 system regulates alcohol-seeking PJ Ryan, HE Kastman, EV Krstew, KJ Rosengren, MA Hossain, L Churilov, ... Proceedings of the National Academy of Sciences 110 (51), 20789-20794, 2013 | 97 | 2013 |
Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3 LM Haugaard-Kedstrom, F Shabanpoor, MA Hossain, RJ Clark, PJ Ryan, ... Journal of the American Chemical Society 133 (13), 4965-4974, 2011 | 95 | 2011 |
A single-chain derivative of the relaxin hormone is a functionally selective agonist of the G protein-coupled receptor, RXFP1 MA Hossain, M Kocan, ST Yao, SG Royce, VB Nair, C Siwek, NA Patil, ... Chemical science 7 (6), 3805-3819, 2016 | 92 | 2016 |