| Neuronal autophagy and neurodegenerative diseases JH Son, JH Shim, KH Kim, JY Ha, JY Han Experimental & molecular medicine 44 (2), 89-98, 2012 | 383 | 2012 |
| CAG repeat not polyglutamine length determines timing of Huntington’s disease onset JM Lee, K Correia, J Loupe, KH Kim, D Barker, EP Hong, MJ Chao, ... Cell 178 (4), 887-900. e14, 2019 | 313 | 2019 |
| Permanent inactivation of Huntington's disease mutation by personalized allele-specific CRISPR/Cas9 JW Shin, KH Kim, MJ Chao, RS Atwal, T Gillis, ME MacDonald, JF Gusella, ... Human molecular genetics 25 (20), 4566-4576, 2016 | 313 | 2016 |
| β-amyloid precursor protein is a direct cleavage target of HtrA2 serine protease: implications for the physiological function of HtrA2 in the mitochondria HJ Park, SS Kim, YM Seong, KH Kim, HG Goo, EJ Yoon, S Kang, H Rhim Journal of Biological Chemistry 281 (45), 34277-34287, 2006 | 115 | 2006 |
| Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington’s disease knock-in mice is blocked by Mlh1 knock-out JM Loupe, RM Pinto, KH Kim, T Gillis, JS Mysore, MA Andrew, ... Human molecular genetics 29 (18), 3044-3053, 2020 | 60 | 2020 |
| The antioxidant Trolox helps recovery from the familial Parkinson's disease-specific mitochondrial deficits caused by PINK1-and DJ-1-deficiency in dopaminergic neuronal cells JH Shim, SH Yoon, KH Kim, JY Han, JY Ha, DH Hyun, SH Paek, UJ Kang, ... Mitochondrion 11 (5), 707-715, 2011 | 59 | 2011 |
| Rescue of PINK1 protein null-specific mitochondrial complex IV deficits by ginsenoside Re activation of nitric oxide signaling KH Kim, K Song, SH Yoon, O Shehzad, YS Kim, JH Son Journal of Biological Chemistry 287 (53), 44109-44120, 2012 | 56 | 2012 |
| Genetic and functional analyses point to FAN1 as the source of multiple Huntington disease modifier effects KH Kim, EP Hong, JW Shin, MJ Chao, J Loupe, T Gillis, JS Mysore, ... The American Journal of Human Genetics 107 (1), 96-110, 2020 | 54 | 2020 |
| The Genetic Modifiers of Motor OnsetAge (GeM MOA) website: Genome-wide association analysis for genetic modifiers of Huntington’s disease K Correia, D Harold, KH Kim, P Holmans, L Jones, M Orth, RH Myers, ... Journal of Huntington's disease 4 (3), 279-284, 2015 | 39 | 2015 |
| Nitric oxide induction of Parkin translocation in PTEN-induced putative kinase 1 (PINK1) deficiency: functional role of neuronal nitric oxide synthase during mitophagy JY Han, MJ Kang, KH Kim, PL Han, HS Kim, JY Ha, JH Son Journal of Biological Chemistry 290 (16), 10325-10335, 2015 | 36 | 2015 |
| Genetic risk underlying psychiatric and cognitive symptoms in Huntington’s disease N Ellis, A Tee, B McAllister, T Massey, D McLauchlan, T Stone, K Correia, ... Biological Psychiatry 87 (9), 857-865, 2020 | 35 | 2020 |
| Population-specific genetic modification of Huntington's disease in Venezuela MJ Chao, KH Kim, JW Shin, D Lucente, VC Wheeler, H Li, JC Roach, ... PLoS genetics 14 (5), e1007274, 2018 | 33 | 2018 |
| Sequence-level analysis of the major European Huntington disease haplotype JM Lee, KH Kim, A Shin, MJ Chao, KA Elneel, T Gillis, JS Mysore, ... The American Journal of Human Genetics 97 (3), 435-444, 2015 | 27 | 2015 |
| Mitochondrial dysfunction of immortalized human adipose tissue-derived mesenchymal stromal cells from patients with Parkinson's disease HE Moon, SH Yoon, YS Hur, HW Park, JY Ha, KH Kim, JH Shim, SH Yoo, ... Experimental neurobiology 22 (4), 283, 2013 | 24 | 2013 |
| PINK1 gene knockdown leads to increased binding of parkin with actin filament KH Kim, JH Son Neuroscience letters 468 (3), 272-276, 2010 | 19 | 2010 |
| Novel allele-specific quantification methods reveal no effects of adult onset CAG repeats on HTT mRNA and protein levels A Shin, B Shin, JW Shin, KH Kim, RS Atwal, JM Hope, T Gillis, JD Leszyk, ... Human Molecular Genetics 26 (7), 1258-1267, 2017 | 14 | 2017 |
| The sCMV IE enhancer/promoter system for high-level expression and efficient functional studies of target genes in mammalian cells and zebrafish GY Kim, JM Moon, JH Han, KH Kim, H Rhim Biotechnology letters 33, 1319-1326, 2011 | 10 | 2011 |
| Full sequence of mutant huntingtin 3′-untranslated region and modulation of its gene regulatory activity by endogenous microRNA KH Kim, K Abu Elneel, JW Shin, JW Keum, D Seong, S Kwak, R Lee, ... Journal of human genetics 64 (10), 995-1004, 2019 | 6 | 2019 |
| Inhibitory Effort of the N-terminal GST on the Tautomerase Activity of Macrophage Migration Inhibitory Factor H Eun-hye, R Hyangshuk Journal of Life Science 15 (6), 961-967, 2005 | 4 | 2005 |
| Purification of human HtrA1 expressed in E. coli and characterization of its serine protease activity KH Kim, SS Kim, GY Kim, HS Rhim Journal of Life Science 16 (7), 1133-1140, 2006 | 2 | 2006 |
Jun Wan ShinDepartment of Neurology, Harvard Medical School and Center for Human Genetic Research, MGH在 mgh.harvard.edu 的电子邮件经过验证
