| Design, synthesis, and biological evaluation of ester and ether derivatives of antisickling agent 5-HMF for the treatment of sickle cell disease GG Xu, PP Pagare, MS Ghatge, RP Safo, A Gazi, Q Chen, T David, ... Molecular pharmaceutics 14 (10), 3499-3511, 2017 | 60 | 2017 |
| Uracil-coumarin based hybrid molecules as potent anti-cancer and anti-bacterial agents M Sanduja, J Gupta, H Singh, PP Pagare, A Rana Journal of Saudi Chemical Society 24 (2), 251-266, 2020 | 52 | 2020 |
| Rational design of pyridyl derivatives of vanillin for the treatment of sickle cell disease PP Pagare, MS Ghatge, FN Musayev, TM Deshpande, Q Chen, C Braxton, ... Bioorganic & medicinal chemistry 26 (9), 2530-2538, 2018 | 39 | 2018 |
| Crystal structure of carbonmonoxy sickle hemoglobin in R-state conformation MS Ghatge, MH Ahmed, ASM Omar, PP Pagare, S Rosef, GE Kellogg, ... Journal of structural biology 194 (3), 446-450, 2016 | 39 | 2016 |
| A Chemical Biology Approach to the Chaperome in Cancer—HSP90 and Beyond GC Tony Taldone, Tai Wang, Anna Rodina, Naga Vara Kishore Pillarsetty ... Cold Spring Harbor Perspectives in Biology, 2019 | 36* | 2019 |
| Rational modification of vanillin derivatives to stereospecifically destabilize sickle hemoglobin polymer formation TM Deshpande, PP Pagare, MS Ghatge, Q Chen, FN Musayev, J Venitz, ... Acta Crystallographica Section D: Structural Biology 74 (10), 956-964, 2018 | 26 | 2018 |
| VZHE-039, a novel antisickling agent that prevents erythrocyte sickling under both hypoxic and anoxic conditions O Abdulmalik, PP Pagare, B Huang, GG Xu, MS Ghatge, X Xu, Q Chen, ... Scientific Reports 10 (1), 20277, 2020 | 19 | 2020 |
| Rational approaches for the design of various GABA modulators and their clinical progression K Bhagat, JV Singh, PP Pagare, N Kumar, A Sharma, G Kaur, ... Molecular diversity 25, 551-601, 2021 | 14 | 2021 |
| Drug discovery efforts toward inhibitors of canonical Wnt/β-catenin signaling pathway in the treatment of cancer: A composition-of-matter review (2010–2020) A Morris, PP Pagare, J Li, Y Zhang Drug discovery today 27 (4), 1115-1127, 2022 | 13 | 2022 |
| Modulating hemoglobin allostery for treatment of sickle cell disease: current progress and intellectual property PP Pagare, A Rastegar, O Abdulmalik, AM Omar, Y Zhang, A Fleischman, ... Expert opinion on therapeutic patents 32 (2), 115-130, 2022 | 11 | 2022 |
| Design, synthesis, and biological evaluation of NAP isosteres: a switch from peripheral to central nervous system acting mu-opioid receptor antagonists PP Pagare, M Li, Y Zheng, AS Kulkarni, S Obeng, B Huang, C Ruiz, ... Journal of medicinal chemistry 65 (6), 5095-5112, 2022 | 9 | 2022 |
| Exploration of structure–activity relationship of aromatic aldehydes bearing pyridinylmethoxy-methyl esters as novel antisickling agents PP Pagare, MS Ghatge, Q Chen, FN Musayev, J Venitz, O Abdulmalik, ... Journal of medicinal chemistry 63 (23), 14724-14739, 2020 | 9 | 2020 |
| Structural alterations of the “address” moiety of NAN leading to the discovery of a novel opioid receptor modulator with reduced hERG toxicity H Ma, PP Pagare, M Li, LT Neel, RE Mendez, JC Gillespie, DL Stevens, ... Journal of medicinal chemistry 66 (1), 577-595, 2022 | 6 | 2022 |
| Novel bivalent ligands carrying potential antinociceptive effects by targeting putative mu opioid receptor and chemokine receptor CXCR4 heterodimers H Ma, M Li, PP Pagare, H Wang, N Nassehi, EJ Santos, SS Negus, ... Bioorganic chemistry 120, 105641, 2022 | 6 | 2022 |
| Structure activity relationship exploration of 5-hydroxy-2-(3-phenylpropyl) chromones as a unique 5-HT2B receptor antagonist scaffold M Kim, M Truss, PP Pagare, MA Essandoh, Y Zhang, DA Williams Bioorganic & Medicinal Chemistry Letters 30 (21), 127511, 2020 | 6 | 2020 |
| Structural modification of azolylacryloyl derivatives yields a novel class of covalent modifiers of hemoglobin as potential antisickling agents AM Omar, T David, PP Pagare, MS Ghatge, Q Chen, A Mehta, Y Zhang, ... Medchemcomm 10 (11), 1900-1906, 2019 | 6 | 2019 |
| Understanding the role of glucose regulated protein 170 (GRP170) as a nucleotide exchange factor through molecular simulations PP Pagare, H Wang, XY Wang, Y Zhang Journal of Molecular Graphics and Modelling 85, 160-170, 2018 | 6 | 2018 |
| Preclinical characterization and development on NAQ as a mu opioid receptor partial agonist for opioid use disorder treatment PP Pagare, S Obeng, B Huang, MM Marcus, KL Nicholson, AE Townsend, ... ACS Pharmacology & Translational Science 5 (11), 1197-1209, 2022 | 5 | 2022 |
| Exploration of naphthoquinone analogs in targeting the TCF-DNA interaction to inhibit the Wnt/β-catenin signaling pathway A Morris, R Hoyle, PP Pagare, SU Zaman, Z Ma, J Li, Y Zhang Bioorganic Chemistry 124, 105812, 2022 | 4 | 2022 |
| Improving the solubility and oral bioavailability of a novel aromatic aldehyde antisickling agent (PP10) for the treatment of sickle cell disease TA Ahmed, KM El-Say, FI Abd-Allah, AM Omar, ME El-Araby, ... Pharmaceutics 13 (8), 1148, 2021 | 4 | 2021 |
Martin K SafoVirginia Commonwealth University在 vcu.edu 的电子邮件经过验证
