| A mechanism of resistance to gefitinib mediated by cellular reprogramming and the acquisition of an FGF2-FGFR1 autocrine growth loop KE Ware, TK Hinz, E Kleczko, KR Singleton, LA Marek, BA Helfrich, ... Oncogenesis 2 (3), e39-e39, 2013 | 258 | 2013 |
| A patient tumor transplant model of squamous cell cancer identifies PI3K inhibitors as candidate therapeutics in defined molecular bins SB Keysar, DP Astling, RT Anderson, BW Vogler, DW Bowles, JJ Morton, ... Molecular oncology 7 (4), 776-790, 2013 | 174 | 2013 |
| Resistance to ROS1 Inhibition Mediated by EGFR Pathway Activation in Non-Small Cell KD Davies, S Mahale, DP Astling, DL Aisner, AT Le | 163* | 2013 |
| High-efficiency RNA-based reprogramming of human primary fibroblasts I Kogut, SM McCarthy, M Pavlova, DP Astling, X Chen, A Jakimenko, ... Nature communications 9 (1), 745, 2018 | 152 | 2018 |
| XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer JJ Morton, G Bird, SB Keysar, DP Astling, TR Lyons, RT Anderson, ... Oncogene 35 (3), 290-300, 2016 | 138 | 2016 |
| Localization of a bacterial cytoplasmic receptor is dynamic and changes with cell-cell contacts EMF Mauriello, DP Astling, O Sliusarenko, DR Zusman Proceedings of the National Academy of Sciences 106 (12), 4852-4857, 2009 | 81 | 2009 |
| Obesity and overfeeding affecting both tumor and systemic metabolism activates the progesterone receptor to contribute to postmenopausal breast cancer ED Giles, EA Wellberg, DP Astling, SM Anderson, AD Thor, S Jindal, ... Cancer research 72 (24), 6490-6501, 2012 | 76 | 2012 |
| Phase I study of oral rigosertib (ON 01910. Na), a dual inhibitor of the PI3K and Plk1 pathways, in adult patients with advanced solid malignancies DW Bowles, JR Diamond, ET Lam, CD Weekes, DP Astling, RT Anderson, ... Clinical Cancer Research 20 (6), 1656-1665, 2014 | 72 | 2014 |
| Finished sequence and assembly of the DUF1220-rich 1q21 region using a haploid human genome M O’Bleness, VB Searles, CM Dickens, D Astling, D Albracht, ACY Mak, ... BMC genomics 15 (1), 1-12, 2014 | 62 | 2014 |
| CNS Aquaporin‐4‐specific B cells connect with multiple B‐cell compartments in neuromyelitis optica spectrum disorder MC Kowarik, D Astling, C Gasperi, S Wemlinger, H Schumann, ... Annals of clinical and translational neurology 4 (6), 369-380, 2017 | 57 | 2017 |
| A proteomic surrogate for cardiovascular outcomes that is sensitive to multiple mechanisms of change in risk SA Williams, R Ostroff, MA Hinterberg, J Coresh, CM Ballantyne, ... Science Translational Medicine 14 (639), eabj9625, 2022 | 55 | 2022 |
| Differential effects of chemoreceptor methylation‐domain mutations on swarming and development in the social bacterium Myxococcus xanthus DP Astling, JY Lee, DR Zusman Molecular microbiology 59 (1), 45-55, 2006 | 52 | 2006 |
| The dual pathway inhibitor rigosertib is effective in direct patient tumor xenografts of head and neck squamous cell carcinomas RT Anderson, SB Keysar, DW Bowles, MJ Glogowska, DP Astling, ... Molecular cancer therapeutics 12 (10), 1994-2005, 2013 | 36 | 2013 |
| Genome replication in Thermococcus kodakarensis independent of Cdc6 and an origin of replication AM Gehring, DP Astling, R Matsumi, BW Burkhart, Z Kelman, JN Reeve, ... Frontiers in microbiology 8, 2084, 2017 | 33 | 2017 |
| Profiling Chlamydomonas Metabolism under Dark, Anoxic H2-Producing Conditions Using a Combined Proteomic, Transcriptomic, and Metabolomic Approach V Subramanian, A Dubini, DP Astling, LML Laurens, WM Old, ... Journal of proteome research 13 (12), 5431-5451, 2014 | 26 | 2014 |
| An ABC Transporter Plays a Developmental Aggregation Role in Myxococcus xanthus MJ Ward, KC Mok, DP Astling, H Lew, DR Zusman Journal of bacteriology 180 (21), 5697-5703, 1998 | 25 | 1998 |
| Differential effects of fingolimod and natalizumab on B cell repertoires in multiple sclerosis patients MC Kowarik, D Astling, G Lepennetier, A Ritchie, B Hemmer, GP Owens, ... Neurotherapeutics 18, 364-377, 2021 | 23 | 2021 |
| Modified nucleotides may have enhanced early RNA catalysis SK Wolk, WS Mayfield, AD Gelinas, D Astling, J Guillot, EN Brody, ... Proceedings of the National Academy of Sciences 117 (15), 8236-8242, 2020 | 22 | 2020 |
| Orthogonal projection to latent structures solution properties for chemometrics and systems biology data DJ Biagioni, DP Astling, P Graf, MF Davis Journal of chemometrics 25 (9), 514-525, 2011 | 21 | 2011 |
| Intrauterine growth restriction decreases NF-κB signaling in fetal pulmonary artery endothelial cells of fetal sheep RB Dodson, KN Powers, J Gien, PJ Rozance, G Seedorf, D Astling, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 315 (3 …, 2018 | 18 | 2018 |
Aik Choon TanHuntsman Cancer Institute, University of Utah在 hci.utah.edu 的电子邮件经过验证
