Regulation of embryonic stem cell self-renewal by phosphoinositide 3-kinase-dependent signaling NRD Paling, H Wheadon, HK Bone, MJ Welham Journal of Biological Chemistry 279 (46), 48063-48070, 2004 | 537 | 2004 |
Tissue specificity of X-chromosome inactivation patterns RE Gale, H Wheadon, P Boulos, DC Linch | 216 | 1994 |
JAK2/STAT5 inhibition by nilotinib with ruxolitinib contributes to the elimination of CML CD34+ cells in vitro and in vivo P Gallipoli, A Cook, S Rhodes, L Hopcroft, H Wheadon, AD Whetton, ... Blood, The Journal of the American Society of Hematology 124 (9), 1492-1501, 2014 | 163 | 2014 |
X‐chromosome inactivation patterns using HPRT and PGK polymorphisms in haematologically normal and post‐chemotherapy females RE Gale, H Wheadon, DC Linch British journal of haematology 79 (2), 193-197, 1991 | 122 | 1991 |
Oncogenic properties of apoptotic tumor cells in aggressive B cell lymphoma CA Ford, S Petrova, JD Pound, JJLP Voss, L Melville, M Paterson, ... Current Biology 25 (5), 577-588, 2015 | 112 | 2015 |
Complement deficiencies limit CD20 monoclonal antibody treatment efficacy in CLL O Middleton, E Cosimo, E Dobbin, AM McCaig, C Clarke, AM Brant, ... Leukemia 29 (1), 107-114, 2015 | 84 | 2015 |
Deregulated hedgehog pathway signaling is inhibited by the smoothened antagonist LDE225 (Sonidegib) in chronic phase chronic myeloid leukaemia DA Irvine, B Zhang, R Kinstrie, A Tarafdar, H Morrison, VL Campbell, ... Scientific reports 6 (1), 25476, 2016 | 81 | 2016 |
Magnetically levitated mesenchymal stem cell spheroids cultured with a collagen gel maintain phenotype and quiescence NS Lewis, EEL Lewis, M Mullin, H Wheadon, MJ Dalby, CC Berry Journal of tissue engineering 8, 2041731417704428, 2017 | 72 | 2017 |
CD93 is expressed on chronic myeloid leukemia stem cells and identifies a quiescent population which persists after tyrosine kinase inhibitor therapy R Kinstrie, GA Horne, H Morrison, D Irvine, C Munje, EG Castañeda, ... Leukemia 34 (6), 1613-1625, 2020 | 63 | 2020 |
Frequency of clonal remission in acute myeloid leukaemia RE Gale, H Wheadon, AH Goldstone, DC Linch, AK Burnett The Lancet 341 (8838), 138-142, 1993 | 63 | 1993 |
Patterns of Wnt/Fzd/LRP gene expression during embryonic hematopoiesis PM Corrigan, E Dobbin, RW Freeburn, H Wheadon Stem cells and development 18 (5), 759-772, 2009 | 60 | 2009 |
A Quiescent, Regeneration-Responsive Tissue Engineered Mesenchymal Stem Cell Bone Marrow Niche Model via Magnetic Levitation EEL Lewis, H Wheadon, N Lewis, J Yang, M Mullin, A Hursthouse, ... ACS nano 10 (9), 8346-8354, 2016 | 58 | 2016 |
Assessment of X-chromosome inactivation patterns using the hypervariable probe M27 beta in normal hemopoietic cells and acute myeloid leukemic blasts. RE Gale, H Wheadon, DC Linch Leukemia 6 (7), 649-655, 1992 | 55 | 1992 |
Molecular interactions of SHP1 and SHP2 in IL-3-signalling H Wheadon, NRD Paling, MJ Welham Cellular signalling 14 (3), 219-229, 2002 | 44 | 2002 |
Macrophages in acute myeloid leukaemia: Significant players in therapy resistance and patient outcomes KE Miari, ML Guzman, H Wheadon, MTS Williams Frontiers in cell and developmental biology 9, 692800, 2021 | 37 | 2021 |
The application of BH3 mimetics in myeloid leukemias N Parry, H Wheadon, M Copland Cell death & disease 12 (2), 222, 2021 | 37 | 2021 |
Inhibition of NF-κB–mediated signaling by the cyclin-dependent kinase inhibitor CR8 overcomes prosurvival stimuli to induce apoptosis in chronic lymphocytic leukemia cells E Cosimo, AM McCaig, LJM Carter-Brzezinski, H Wheadon, MT Leach, ... Clinical Cancer Research 19 (9), 2393-2405, 2013 | 37 | 2013 |
Targeting self-renewal pathways in myeloid malignancies WA Sands, M Copland, H Wheadon Cell Communication and Signaling 11, 1-13, 2013 | 32 | 2013 |
The Functional Response of Mesenchymal Stem Cells to Electron‐Beam Patterned Elastomeric Surfaces Presenting Micrometer to Nanoscale Heterogeneous Rigidity MJP Biggs, M Fernandez, D Thomas, R Cooper, M Palma, J Liao, T Fazio, ... Advanced materials 29 (39), 1702119, 2017 | 29 | 2017 |
Canonical Wnt signaling promotes early hematopoietic progenitor formation and erythroid specification during embryonic stem cell differentiation A Tarafdar, E Dobbin, P Corrigan, R Freeburn, H Wheadon Plos one 8 (11), e81030, 2013 | 29 | 2013 |