Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster I Bjedov, JM Toivonen, F Kerr, C Slack, J Jacobson, A Foley, L Partridge Cell metabolism 11 (1), 35-46, 2010 | 1243 | 2010 |
A holidic medium for Drosophila melanogaster MDW Piper, E Blanc, R Leitão-Gonçalves, M Yang, X He, NJ Linford, ... Nature methods 11 (1), 100-105, 2014 | 357 | 2014 |
Inhibition of GSK-3 Ameliorates Aβ Pathology in an Adult-Onset Drosophila Model of Alzheimer's Disease O Sofola, F Kerr, I Rogers, R Killick, H Augustin, C Gandy, MJ Allen, ... PLoS genetics 6 (9), e1001087, 2010 | 202 | 2010 |
Lithium promotes longevity through GSK3/NRF2-dependent hormesis JI Castillo-Quan, L Li, KJ Kinghorn, DK Ivanov, LS Tain, C Slack, F Kerr, ... Cell reports 15 (3), 638-650, 2016 | 188 | 2016 |
Glycogen synthase kinase-3 is increased in white cells early in Alzheimer's disease A Hye, F Kerr, N Archer, C Foy, M Poppe, R Brown, G Hamilton, J Powell, ... Neuroscience letters 373 (1), 1-4, 2004 | 173 | 2004 |
Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice R Killick, G Scales, K Leroy, M Causevic, C Hooper, EE Irvine, ... Biochemical and biophysical research communications 386 (1), 257-262, 2009 | 148 | 2009 |
Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease F Kerr, O Sofola-Adesakin, DK Ivanov, J Gatliff, B Gomez Perez-Nievas, ... PLoS genetics 13 (3), e1006593, 2017 | 138 | 2017 |
Increased glucose transport into neurons rescues Aβ toxicity in Drosophila T Niccoli, M Cabecinha, A Tillmann, F Kerr, CT Wong, D Cardenes, ... Current Biology 26 (17), 2291-2300, 2016 | 123 | 2016 |
Molecular mechanisms of lithium action: switching the light on multiple targets for dementia using animal models F Kerr, I Bjedov, O Sofola-Adesakin Frontiers in Molecular Neuroscience 11, 297, 2018 | 78 | 2018 |
PTEN, a negative regulator of PI3 kinase signalling, alters tau phosphorylation in cells by mechanisms independent of GSK-3 F Kerr, A Rickle, N Nayeem, S Brandner, RF Cowburn, S Lovestone FEBS letters 580 (13), 3121-3128, 2006 | 73 | 2006 |
Ageing increases vulnerability to aβ42 toxicity in Drosophila I Rogers, F Kerr, P Martinez, J Hardy, S Lovestone, L Partridge PloS one 7 (7), e40569, 2012 | 57 | 2012 |
Dietary restriction delays aging, but not neuronal dysfunction, in Drosophila models of Alzheimer's disease F Kerr, H Augustin, MDW Piper, C Gandy, MJ Allen, S Lovestone, ... Neurobiology of aging 32 (11), 1977-1989, 2011 | 57 | 2011 |
Deletion of endogenous Tau proteins is not detrimental in Drosophila S Burnouf, S Grönke, H Augustin, J Dols, MK Gorsky, J Werner, F Kerr, ... Scientific reports 6 (1), 23102, 2016 | 45 | 2016 |
Reduced insulin signaling maintains electrical transmission in a neural circuit in aging flies H Augustin, K McGourty, MJ Allen, SK Madem, J Adcott, F Kerr, CT Wong, ... PLoS biology 15 (9), e2001655, 2017 | 28 | 2017 |
Hyperphosphorylation of tau and neurofilaments and activation of CDK5 and ERK1/2 in PTEN-deficient cerebella N Nayeem, F Kerr, H Naumann, J Linehan, S Lovestone, S Brandner Molecular and Cellular Neuroscience 34 (3), 400-408, 2007 | 28 | 2007 |
Activating transcription factor 4-dependent lactate dehydrogenase activation as a protective response to amyloid beta toxicity T Niccoli, F Kerr, I Snoeren, D Fabian, B Aleyakpo, D Ivanov, ... Brain communications 3 (2), fcab053, 2021 | 8 | 2021 |
Dynamic changes in the brain protein interaction network correlates with progression of Aβ42 pathology in Drosophila HM Scholes, A Cryar, F Kerr, D Sutherland, LA Gethings, JPC Vissers, ... Scientific reports 10 (1), 18517, 2020 | 8 | 2020 |
Building a systematic online living evidence summary of COVID-19 research K Hair, ES Sena, E Wilson, G Currie, M Macleod, Z Bahor, C Sena, ... Journal of EAHIL 17 (2), 21-26, 2021 | 2 | 2021 |
School students as Drosophila experimenters F Siyad, J Griffiths, F Janjua, E Jackson, I Rodrigues, F Kerr, D Mackay, ... PLoS Biology 3 (7), e246, 2005 | 2 | 2005 |
Correction: Corrigendum: A holidic medium for Drosophila melanogaster MDW Piper, E Blanc, R Leitão-Gonçalves, M Yang, X He, NJ Linford, ... Nature Methods 12 (11), 1098-1098, 2015 | 1 | 2015 |