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Afroz  S Mohammad
Afroz S Mohammad
Senior Clinical Pharmacologist, Abbvie
在 abbvie.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Alterations in pericyte subpopulations are associated with elevated blood–tumor barrier permeability in experimental brain metastasis of breast cancer
LT Lyle, PR Lockman, CE Adkins, AS Mohammad, E Sechrest, E Hua, ...
Clinical Cancer Research 22 (21), 5287-5299, 2016
1612016
Molecular determinants of blood–brain barrier permeation
WJ Geldenhuys, AS Mohammad, CE Adkins, PR Lockman
Therapeutic delivery 6 (8), 961-971, 2015
1252015
Investigational chemotherapy and novel pharmacokinetic mechanisms for the treatment of breast cancer brain metastases
N Shah, AS Mohammad, P Saralkar, SA Sprowls, SD Vickers, D John, ...
Pharmacological research 132, 47-68, 2018
1242018
Targeting the blood-brain barrier to prevent sepsis-associated cognitive impairment
DC Nwafor, AL Brichacek, AS Mohammad, J Griffith, BP Lucke-Wold, ...
Journal of central nervous system disease 11, 1179573519840652, 2019
1052019
Liposomal irinotecan accumulates in metastatic lesions, crosses the blood-tumor barrier (BTB), and prolongs survival in an experimental model of brain metastases of triple …
AS Mohammad, JI Griffith, CE Adkins, N Shah, E Sechrest, EL Dolan, ...
Pharmaceutical research 35, 1-10, 2018
642018
P-glycoprotein mediated efflux limits substrate and drug uptake in a preclinical brain metastases of breast cancer model
CE Adkins, RK Mittapalli, VK Manda, MI Nounou, AS Mohammad, ...
Frontiers in pharmacology 4, 136, 2013
632013
Quantitative fluorescence microscopy measures vascular pore size in primary and metastatic brain tumors
RK Mittapalli, CE Adkins, KA Bohn, AS Mohammad, JA Lockman, ...
Cancer research 77 (2), 238-246, 2017
612017
Characterization of passive permeability at the blood–tumor barrier in five preclinical models of brain metastases of breast cancer
CE Adkins, AS Mohammad, TB Terrell-Hall, EL Dolan, N Shah, ...
Clinical & experimental metastasis 33, 373-383, 2016
562016
NKTR-102 Efficacy versus irinotecan in a mouse model of brain metastases of breast cancer
CE Adkins, MI Nounou, T Hye, AS Mohammad, T Terrell-Hall, NK Mohan, ...
BMC cancer 15, 1-11, 2015
542015
Brain distribution of a panel of epidermal growth factor receptor inhibitors using cassette dosing in wild-type and Abcb1/Abcg2-deficient mice
M Kim, JK Laramy, AS Mohammad, S Talele, J Fisher, JN Sarkaria, ...
Drug Metabolism and Disposition 47 (4), 393-404, 2019
502019
Novel treatment strategies for brain tumors and metastases
SE El-Habashy, AM Nazief, CE Adkins, MM Wen, AH El-Kamel, ...
Pharmaceutical patent analyst 3 (3), 279-296, 2014
312014
Semi-automated rapid quantification of brain vessel density utilizing fluorescent microscopy
KA Bohn, CE Adkins, RK Mittapalli, TB Terrell-Hall, AS Mohammad, ...
Journal of neuroscience methods 270, 124-131, 2016
292016
Enhancing brain retention of a KIF11 inhibitor significantly improves its efficacy in a mouse model of glioblastoma
G Gampa, RS Kenchappa, AS Mohammad, KE Parrish, M Kim, JF Crish, ...
Scientific reports 10 (1), 6524, 2020
282020
A mouse model of focal vascular injury induces astrocyte reactivity, tau oligomers, and aberrant behavior
AF Logsdon, BP Lucke-Wold, RC Turner, X Li, CE Adkins, AS Mohammad, ...
Archives of neuroscience 4 (2), 2017
282017
Brain distribution of berzosertib: an ataxia telangiectasia and Rad3-related protein inhibitor for the treatment of glioblastoma
S Talele, W Zhang, DM Burgenske, M Kim, AS Mohammad, S Dragojevic, ...
Journal of Pharmacology and Experimental Therapeutics 379 (3), 343-357, 2021
182021
Brain distribution and active efflux of three panRAF inhibitors: considerations in the treatment of melanoma brain metastases
G Gampa, M Kim, AS Mohammad, KE Parrish, AC Mladek, JN Sarkaria, ...
Journal of Pharmacology and Experimental Therapeutics 368 (3), 446-461, 2019
172019
Permeability changes and effect of chemotherapy in brain adjacent to tumor in an experimental model of metastatic brain tumor from breast cancer
AS Mohammad, CE Adkins, N Shah, R Aljammal, JIG Griffith, RM Tallman, ...
BMC cancer 18, 1-10, 2018
152018
Activation of STAT3 through combined SRC and EGFR signaling drives resistance to a mitotic kinesin inhibitor in glioblastoma
RS Kenchappa, A Dovas, MG Argenziano, CT Meyer, LE Stopfer, ...
Cell reports 39 (12), 2022
142022
Drug resistance occurred in a newly characterized preclinical model of lung cancer brain metastasis
N Shah, Z Liu, RM Tallman, A Mohammad, SA Sprowls, PA Saralkar, ...
BMC cancer 20, 1-13, 2020
142020
A novel preclinical method to quantitatively evaluate early-stage metastatic events at the murine blood–brain barrier
CE Adkins, MI Nounou, RK Mittapalli, TB Terrell-Hall, AS Mohammad, ...
Cancer Prevention Research 8 (1), 68-76, 2015
142015
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