Alterations in pericyte subpopulations are associated with elevated blood–tumor barrier permeability in experimental brain metastasis of breast cancer LT Lyle, PR Lockman, CE Adkins, AS Mohammad, E Sechrest, E Hua, ... Clinical Cancer Research 22 (21), 5287-5299, 2016 | 161 | 2016 |
Molecular determinants of blood–brain barrier permeation WJ Geldenhuys, AS Mohammad, CE Adkins, PR Lockman Therapeutic delivery 6 (8), 961-971, 2015 | 125 | 2015 |
Investigational chemotherapy and novel pharmacokinetic mechanisms for the treatment of breast cancer brain metastases N Shah, AS Mohammad, P Saralkar, SA Sprowls, SD Vickers, D John, ... Pharmacological research 132, 47-68, 2018 | 124 | 2018 |
Targeting the blood-brain barrier to prevent sepsis-associated cognitive impairment DC Nwafor, AL Brichacek, AS Mohammad, J Griffith, BP Lucke-Wold, ... Journal of central nervous system disease 11, 1179573519840652, 2019 | 105 | 2019 |
Liposomal irinotecan accumulates in metastatic lesions, crosses the blood-tumor barrier (BTB), and prolongs survival in an experimental model of brain metastases of triple … AS Mohammad, JI Griffith, CE Adkins, N Shah, E Sechrest, EL Dolan, ... Pharmaceutical research 35, 1-10, 2018 | 64 | 2018 |
P-glycoprotein mediated efflux limits substrate and drug uptake in a preclinical brain metastases of breast cancer model CE Adkins, RK Mittapalli, VK Manda, MI Nounou, AS Mohammad, ... Frontiers in pharmacology 4, 136, 2013 | 63 | 2013 |
Quantitative fluorescence microscopy measures vascular pore size in primary and metastatic brain tumors RK Mittapalli, CE Adkins, KA Bohn, AS Mohammad, JA Lockman, ... Cancer research 77 (2), 238-246, 2017 | 61 | 2017 |
Characterization of passive permeability at the blood–tumor barrier in five preclinical models of brain metastases of breast cancer CE Adkins, AS Mohammad, TB Terrell-Hall, EL Dolan, N Shah, ... Clinical & experimental metastasis 33, 373-383, 2016 | 56 | 2016 |
NKTR-102 Efficacy versus irinotecan in a mouse model of brain metastases of breast cancer CE Adkins, MI Nounou, T Hye, AS Mohammad, T Terrell-Hall, NK Mohan, ... BMC cancer 15, 1-11, 2015 | 54 | 2015 |
Brain distribution of a panel of epidermal growth factor receptor inhibitors using cassette dosing in wild-type and Abcb1/Abcg2-deficient mice M Kim, JK Laramy, AS Mohammad, S Talele, J Fisher, JN Sarkaria, ... Drug Metabolism and Disposition 47 (4), 393-404, 2019 | 50 | 2019 |
Novel treatment strategies for brain tumors and metastases SE El-Habashy, AM Nazief, CE Adkins, MM Wen, AH El-Kamel, ... Pharmaceutical patent analyst 3 (3), 279-296, 2014 | 31 | 2014 |
Semi-automated rapid quantification of brain vessel density utilizing fluorescent microscopy KA Bohn, CE Adkins, RK Mittapalli, TB Terrell-Hall, AS Mohammad, ... Journal of neuroscience methods 270, 124-131, 2016 | 29 | 2016 |
Enhancing brain retention of a KIF11 inhibitor significantly improves its efficacy in a mouse model of glioblastoma G Gampa, RS Kenchappa, AS Mohammad, KE Parrish, M Kim, JF Crish, ... Scientific reports 10 (1), 6524, 2020 | 28 | 2020 |
A mouse model of focal vascular injury induces astrocyte reactivity, tau oligomers, and aberrant behavior AF Logsdon, BP Lucke-Wold, RC Turner, X Li, CE Adkins, AS Mohammad, ... Archives of neuroscience 4 (2), 2017 | 28 | 2017 |
Brain distribution of berzosertib: an ataxia telangiectasia and Rad3-related protein inhibitor for the treatment of glioblastoma S Talele, W Zhang, DM Burgenske, M Kim, AS Mohammad, S Dragojevic, ... Journal of Pharmacology and Experimental Therapeutics 379 (3), 343-357, 2021 | 18 | 2021 |
Brain distribution and active efflux of three panRAF inhibitors: considerations in the treatment of melanoma brain metastases G Gampa, M Kim, AS Mohammad, KE Parrish, AC Mladek, JN Sarkaria, ... Journal of Pharmacology and Experimental Therapeutics 368 (3), 446-461, 2019 | 17 | 2019 |
Permeability changes and effect of chemotherapy in brain adjacent to tumor in an experimental model of metastatic brain tumor from breast cancer AS Mohammad, CE Adkins, N Shah, R Aljammal, JIG Griffith, RM Tallman, ... BMC cancer 18, 1-10, 2018 | 15 | 2018 |
Activation of STAT3 through combined SRC and EGFR signaling drives resistance to a mitotic kinesin inhibitor in glioblastoma RS Kenchappa, A Dovas, MG Argenziano, CT Meyer, LE Stopfer, ... Cell reports 39 (12), 2022 | 14 | 2022 |
Drug resistance occurred in a newly characterized preclinical model of lung cancer brain metastasis N Shah, Z Liu, RM Tallman, A Mohammad, SA Sprowls, PA Saralkar, ... BMC cancer 20, 1-13, 2020 | 14 | 2020 |
A novel preclinical method to quantitatively evaluate early-stage metastatic events at the murine blood–brain barrier CE Adkins, MI Nounou, RK Mittapalli, TB Terrell-Hall, AS Mohammad, ... Cancer Prevention Research 8 (1), 68-76, 2015 | 14 | 2015 |