Heterocyclic rimantadine analogues with antiviral activity G Zoidis, C Fytas, I Papanastasiou, GB Foscolos, G Fytas, E Padalko, ... Bioorganic & medicinal chemistry 14 (10), 3341-3348, 2006 | 151 | 2006 |
An Overview on Target-Based Drug Design against Kinetoplastid Protozoan Infections: Human African Trypanosomiasis, Chagas Disease and Leishmaniases V Kourbeli, E Chontzopoulou, K Moschovou, D Pavlos, ... Molecules 26 (15), 4629, 2021 | 81 | 2021 |
Design, synthesis, and trypanocidal activity of new aminoadamantane derivatives I Papanastasiou, A Tsotinis, N Kolocouris, SR Prathalingam, JM Kelly Journal of medicinal chemistry 51 (5), 1496-1500, 2008 | 78 | 2008 |
Novel 1′, 1′-chain substituted hexahydrocannabinols: 9β-hydroxy-3-(1-hexyl-cyclobut-1-yl)-hexahydrocannabinol (AM2389) a highly potent cannabinoid receptor 1 (CB1) agonist SP Nikas, SO Alapafuja, I Papanastasiou, CA Paronis, VG Shukla, ... Journal of medicinal chemistry 53 (19), 6996-7010, 2010 | 72 | 2010 |
The novel GABA adamantane derivative (AdGABA): design, synthesis, and activity relationship with gabapentin G Zoidis, I Papanastasiou, I Dotsikas, A Sandoval, RG Dos Santos, ... Bioorganic & medicinal chemistry 13 (8), 2791-2798, 2005 | 54 | 2005 |
Sigma receptor (σR) ligands with antiproliferative and anticancer activity MO Georgiadis, O Karoutzou, AS Foscolos, I Papanastasiou Molecules 22 (9), 1408, 2017 | 53 | 2017 |
Pineal hormone melatonin as an adjuvant treatment for COVID‑19 M Vlachou, A Siamidi, A Dedeloudi, SK Konstantinidou, IP Papanastasiou International Journal of Molecular Medicine 47 (4), 1-1, 2021 | 43 | 2021 |
Design and synthesis of new adamantyl-substituted antileishmanial ether phospholipids I Papanastasiou, KC Prousis, K Georgikopoulou, T Pavlidis, E Scoulica, ... Bioorganic & medicinal chemistry letters 20 (18), 5484-5487, 2010 | 40 | 2010 |
Synthesis, σ1, σ2-receptors binding affinity and antiproliferative action of new C1-substituted adamantanes S Riganas, I Papanastasiou, GB Foscolos, A Tsotinis, JJ Bourguignon, ... Bioorganic & medicinal chemistry 20 (10), 3323-3331, 2012 | 30 | 2012 |
New adamantane phenylalkylamines with σ-receptor binding affinity and anticancer activity, associated with putative antagonism of neuropathic pain S Riganas, I Papanastasiou, GB Foscolos, A Tsotinis, G Serin, JF Mirjolet, ... Journal of medicinal chemistry 55 (22), 10241-10261, 2012 | 27 | 2012 |
Design and Synthesis of Trypanosoma brucei Active 1‐Alkyloxy and 1‐Benzyloxyadamantano 2‐Guanylhydrazones I Papanastasiou, A Tsotinis, G Zoidis, N Kolocouris, SR Prathalingam, ... ChemMedChem: Chemistry Enabling Drug Discovery 4 (7), 1059-1062, 2009 | 22 | 2009 |
New adamantane derivatives with sigma affinity and antiproliferative activity S Riganas, I Papanastasiou, G B Foscolos, A Tsotinis, K Dimas, ... Medicinal Chemistry 8 (4), 569-586, 2012 | 20 | 2012 |
Microwave-assisted synthesis of sodium sulfonates precursors of sulfonyl chlorides and fluorides SO Alapafuja, SP Nikas, VG Shukla, I Papanastasiou, A Makriyannis Tetrahedron letters 50 (50), 7028-7031, 2009 | 20 | 2009 |
Repurposing current therapeutic regimens against SARS-CoV-2 S K. Konstantinidou, I P. Papanastasiou Experimental and therapeutic medicine 20 (3), 1845-1855, 2020 | 19 | 2020 |
4-(1-Adamantyl) phenylalkylamines with potential antiproliferative activity A Koperniku, AS Foscolos, I Papanastasiou, G B Foscolos, A Tsotinis, ... Letters in Organic Chemistry 13 (3), 171-176, 2016 | 18 | 2016 |
New aminoadamantane derivatives with antiproliferative activity I Papanastasiou, A Tsotinis, N Kolocouris, SP Nikas, A Vamvakides Medicinal Chemistry Research 23, 1966-1975, 2014 | 18 | 2014 |
Chemical probes for blocking of influenza A M2 wild-type and S31N channels C Tzitzoglaki, K McGuire, P Lagarias, A Konstantinidi, A Hoffmann, ... ACS Chemical Biology 15 (9), 2331-2337, 2020 | 17 | 2020 |
New hydrazones of 5-nitro-2-furaldehyde with adamantanealkanohydrazides: synthesis and in vitro trypanocidal activity AS Foscolos, I Papanastasiou, GB Foscolos, A Tsotinis, TF Kellici, ... MedChemComm 7 (6), 1229-1236, 2016 | 17 | 2016 |
Synthesis and trypanocidal action of new adamantane substituted imidazolines A Koperniku, I Papanastasiou, GB Foscolos, A Tsotinis, MC Taylor, ... MedChemComm 4 (5), 856-859, 2013 | 14 | 2013 |
Synthesis of conformationally constrained adamantane imidazolines with trypanocidal activity I Papanastasiou, A Tsotinis, GB Foscolos, SR Prathalingam, JM Kelly Journal of heterocyclic chemistry 45 (5), 1401-1406, 2008 | 14 | 2008 |