关注
Jordi Rodon
标题
引用次数
引用次数
年份
Development of PI3K inhibitors: lessons learned from early clinical trials
J Rodon, R Dienstmann, V Serra, J Tabernero
Nature reviews Clinical oncology 10 (3), 143-153, 2013
8612013
Phase I, dose-escalation study of BKM120, an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors
JC Bendell, J Rodon, HA Burris, M de Jonge, J Verweij, D Birle, ...
J Clin Oncol 30 (3), 282-290, 2012
7832012
Actively personalized vaccination trial for newly diagnosed glioblastoma
N Hilf, S Kuttruff-Coqui, K Frenzel, V Bukur, S Stevanović, ...
Nature 565 (7738), 240-245, 2019
7612019
Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma
L De Mattos-Arruda, R Mayor, CKY Ng, B Weigelt, F Martínez-Ricarte, ...
Nature communications 6 (1), 8839, 2015
7452015
HER kinase inhibition in patients with HER2-and HER3-mutant cancers
DM Hyman, SA Piha-Paul, H Won, J Rodon, C Saura, GI Shapiro, D Juric, ...
Nature 554 (7691), 189-194, 2018
6902018
TGF-β Receptor Inhibitors Target the CD44high/Id1high Glioma-Initiating Cell Population in Human Glioblastoma
J Anido, A Sáez-Borderías, A Gonzàlez-Juncà, L Rodón, G Folch, ...
Cancer cell 18 (6), 655-668, 2010
6762010
PI3K inhibition impairs BRCA1/2 expression and sensitizes BRCA-proficient triple-negative breast cancer to PARP inhibition
YH Ibrahim, C García-García, V Serra, L He, K Torres-Lockhart, A Prat, ...
Cancer discovery 2 (11), 1036-1047, 2012
5942012
Picking the point of inhibition: a comparative review of PI3K/AKT/mTOR pathway inhibitors
R Dienstmann, J Rodon, V Serra, J Tabernero
Molecular cancer therapeutics 13 (5), 1021-1031, 2014
5232014
Cancer Genome Interpreter annotates the biological and clinical relevance of tumor alterations
D Tamborero, C Rubio-Perez, J Deu-Pons, MP Schroeder, A Vivancos, ...
Genome medicine 10, 1-8, 2018
4762018
Cancer Genome Interpreter annotates the biological and clinical relevance of tumor alterations
D Tamborero, C Rubio-Perez, J Deu-Pons, MP Schroeder, A Vivancos, ...
Genome medicine 10, 1-8, 2018
4742018
Genomic and transcriptomic profiling expands precision cancer medicine: the WINTHER trial
J Rodon, JC Soria, R Berger, WH Miller, E Rubin, A Kugel, A Tsimberidou, ...
Nature medicine 25 (5), 751-758, 2019
4442019
Phase I, pharmacokinetic, and pharmacodynamic study of AMG 479, a fully human monoclonal antibody to insulin-like growth factor receptor 1
AW Tolcher, J Sarantopoulos, A Patnaik, K Papadopoulos, CC Lin, ...
Journal of Clinical Oncology 27 (34), 5800-5807, 2009
4122009
Genomic aberrations in the FGFR pathway: opportunities for targeted therapies in solid tumors
R Dienstmann, J Rodon, A Prat, J Perez-Garcia, B Adamo, E Felip, ...
Annals of oncology 25 (3), 552-563, 2014
4042014
Phase I dose-escalation study of JNJ-42756493, an oral pan–Fibroblast growth factor receptor inhibitor, in patients with advanced solid tumors
J Tabernero, R Bahleda, R Dienstmann, JR Infante, A Mita, A Italiano, ...
Journal of Clinical Oncology 33 (30), 3401-3408, 2015
3972015
Phosphatidylinositol 3-kinase α–selective inhibition with alpelisib (BYL719) in PIK3CA-altered solid tumors: results from the first-in-human study
D Juric, J Rodon, J Tabernero, F Janku, HA Burris, JHM Schellens, ...
Journal of Clinical Oncology 36 (13), 1291, 2018
3692018
PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor–positive breast cancer
A Bosch, Z Li, A Bergamaschi, H Ellis, E Toska, A Prat, JJ Tao, DE Spratt, ...
Science translational medicine 7 (283), 283ra51-283ra51, 2015
3522015
mTORC1 inhibition is required for sensitivity to PI3K p110α inhibitors in PIK3CA-mutant breast cancer
M Elkabets, S Vora, D Juric, N Morse, M Mino-Kenudson, T Muranen, ...
Science translational medicine 5 (196), 196ra99-196ra99, 2013
3142013
AXL mediates resistance to PI3Kα inhibition by activating the EGFR/PKC/mTOR axis in head and neck and esophageal squamous cell carcinomas
M Elkabets, E Pazarentzos, D Juric, Q Sheng, RA Pelossof, S Brook, ...
Cancer cell 27 (4), 533-546, 2015
3102015
BRAF inhibition in BRAFV600-mutant gliomas: results from the VE-BASKET study
T Kaley, M Touat, V Subbiah, A Hollebecque, J Rodon, AC Lockhart, ...
Journal of Clinical Oncology 36 (35), 3477, 2018
2982018
Advances in HER2-targeted therapy: novel agents and opportunities beyond breast and gastric cancer
F Meric-Bernstam, AM Johnson, EEI Dumbrava, K Raghav, K Balaji, ...
Clinical Cancer Research 25 (7), 2033-2041, 2019
2792019
系统目前无法执行此操作,请稍后再试。
文章 1–20