The production of recombinant pharmaceutical proteins in plants JKC Ma, PMW Drake, P Christou Nature reviews genetics 4 (10), 794-805, 2003 | 1381 | 2003 |
Genetically modified plants and human health S Key, JKC Ma, PMW Drake Journal of the Royal Society of Medicine 101 (6), 290-298, 2008 | 320 | 2008 |
A murine monoclonal antibody produced in transgenic plants with plant-specific glycans is not immunogenic in mice D Chargelegue, ND Vine, CJ van Dolleweerd, PMW Drake, JKC Ma Transgenic research 9, 187-194, 2000 | 184 | 2000 |
Antibody processing and engineering in plants, and new strategies for vaccine production JKC Ma, PMW Drake, D Chargelegue, P Obregon, A Prada Vaccine 23 (15), 1814-1818, 2005 | 134 | 2005 |
ER–resident chaperone interactions with recombinant antibodies in transgenic plants J Nuttall, N Vine, JL Hadlington, P Drake, L Frigerio, JKC Ma European Journal of Biochemistry 269 (24), 6042-6051, 2002 | 119 | 2002 |
HIV‐1 p24–immunoglobulin fusion molecule: a new strategy for plant‐based protein production P Obregon, D Chargelegue, PMW Drake, A Prada, J Nuttall, L Frigerio, ... Plant Biotechnology Journal 4 (2), 195-207, 2006 | 105 | 2006 |
Rhizosecretion of a monoclonal antibody protein complex from transgenic tobacco roots PMW Drake, DM Chargelegue, ND Vine, CJ van Dolleweerd, P Obregon, ... Plant molecular biology 52, 233-241, 2003 | 95 | 2003 |
Transgenic plant production of Cyanovirin‐N, an HIV microbicide A Sexton, PM Drake, N Mahmood, SJ Harman, RJ Shattock, JKC Ma The FASEB journal 20 (2), 356-358, 2006 | 93 | 2006 |
Highly immunogenic and protective recombinant vaccine candidate expressed in transgenic plants D Chargelegue, PMW Drake, P Obregon, A Prada, N Fairweather, ... Infection and immunity 73 (9), 5915-5922, 2005 | 93 | 2005 |
Development of rhizosecretion as a production system for recombinant proteins from hydroponic cultivated tobacco PMW Drake, T Barbi, A Sexton, E McGowan, J Stadlmann, C Navarre, ... The FASEB Journal 23 (10), 3581-3589, 2009 | 86 | 2009 |
Characterization of a plant-produced recombinant human secretory IgA with broad neutralizing activity against HIV M Paul, R Reljic, K Klein, PMW Drake, C Van Dolleweerd, M Pabst, ... MAbs 6 (6), 1585-1597, 2014 | 62 | 2014 |
Antibody degradation in tobacco plants: a predominantly apoplastic process VK Hehle, MJ Paul, PM Drake, JKC Ma, CJ van Dolleweerd BMC biotechnology 11, 1-12, 2011 | 62 | 2011 |
Transgenic plants for vaccine production: expectations and limitations D Chargelegue, P Obregon, PMW Drake Trends in Plant Science 6 (11), 495-496, 2001 | 56 | 2001 |
Plant‐derived recombinant immune complexes as self‐adjuvanting TB immunogens for mucosal boosting of BCG I Pepponi, GR Diogo, E Stylianou, CJ van Dolleweerd, PMW Drake, ... Plant biotechnology journal 12 (7), 840-850, 2014 | 54 | 2014 |
Molecular pharming: future targets and aspirations M Paul, C Dolleweerd, PMW Drake, R Reljic, H Thangaraj, T Barbi, ... Human Vaccines 7 (3), 375-382, 2011 | 49 | 2011 |
Recombinant biologic products versus nutraceuticals from plants–a regulatory choice? PMW Drake, TH Szeto, MJ Paul, AYH Teh, JKC Ma British Journal of Clinical Pharmacology 83 (1), 82-87, 2017 | 45 | 2017 |
High‐yield production of a human monoclonal IgG by rhizosecretion in hydroponic tobacco cultures LM Madeira, TH Szeto, M Henquet, N Raven, J Runions, J Huddleston, ... Plant Biotechnology Journal 14 (2), 615-624, 2016 | 44 | 2016 |
Optimisation of contained Nicotiana tabacum cultivation for the production of recombinant protein pharmaceuticals R Colgan, CJ Atkinson, M Paul, S Hassan, PMW Drake, AL Sexton, ... Transgenic research 19, 241-256, 2010 | 44 | 2010 |
Transgenic plants expressing antibodies: a model for phytoremediation PMW Drake, D Chargelegue, ND Vine, CJ Van Dolleweerd, P Obregon, ... The FASEB Journal 16 (14), 1855-1860, 2002 | 36 | 2002 |
Transformation of Althaea officinalis L. by Agrobacterium rhizogenes for the production of transgenic roots expressing the anti-HIV microbicide cyanovirin-N PMW Drake, L de Moraes Madeira, TH Szeto, JKC Ma Transgenic research 22, 1225-1229, 2013 | 33 | 2013 |