| The immune landscape of cancer V Thorsson, DL Gibbs, SD Brown, D Wolf, DS Bortone, THO Yang, ... Immunity 48 (4), 812-830. e14, 2018 | 4499 | 2018 |
| A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone SA Rosenberg, MT Lotze, LM Muul, AE Chang, FP Avis, S Leitman, ... New England Journal of Medicine 316 (15), 889-897, 1987 | 3634 | 1987 |
| Identification of the von Hippel-Lindau disease tumor suppressor gene F Latif, K Tory, J Gnarra, M Yao, FM Duh, ML Orcutt, T Stackhouse, ... Science 260 (5112), 1317-1320, 1993 | 3543 | 1993 |
| An integrated TCGA pan-cancer clinical data resource to drive high-quality survival outcome analytics J Liu, T Lichtenberg, KA Hoadley, LM Poisson, AJ Lazar, AD Cherniack, ... Cell 173 (2), 400-416. e11, 2018 | 2673 | 2018 |
| The molecular taxonomy of primary prostate cancer A Abeshouse, J Ahn, R Akbani, A Ally, S Amin, CD Andry, M Annala, ... Cell 163 (4), 1011-1025, 2015 | 2635 | 2015 |
| Oncogenic signaling pathways in the cancer genome atlas F Sanchez-Vega, M Mina, J Armenia, WK Chatila, A Luna, KC La, ... Cell 173 (2), 321-337. e10, 2018 | 2504 | 2018 |
| Comprehensive characterization of cancer driver genes and mutations MH Bailey, C Tokheim, E Porta-Pardo, S Sengupta, D Bertrand, ... Cell 173 (2), 371-385. e18, 2018 | 2209 | 2018 |
| Cell-of-origin patterns dominate the molecular classification of 10,000 tumors from 33 types of cancer KA Hoadley, C Yau, T Hinoue, DM Wolf, AJ Lazar, E Drill, R Shen, ... Cell 173 (2), 291-304. e6, 2018 | 2053 | 2018 |
| Mutations of the VHL tumour suppressor gene in renal carcinoma JR Gnarra, K Tory, Y Weng, L Schmidt, MH Wei, H Li, F Latif, S Liu, ... Nature genetics 7 (1), 85-90, 1994 | 2050 | 1994 |
| Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma. JG Herman, F Latif, Y Weng, MI Lerman, B Zbar, S Liu, D Samid, DS Duan, ... Proceedings of the National Academy of Sciences 91 (21), 9700-9704, 1994 | 1964 | 1994 |
| Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas L Schmidt, FM Duh, F Chen, T Kishida, G Glenn, P Choyke, SW Scherer, ... Nature genetics 16 (1), 68-73, 1997 | 1912 | 1997 |
| von Hippel-Lindau disease RR Lonser, GM Glenn, MC Walther, EY Chew, SK Libutti, WM Linehan, ... The Lancet 361 (9374), 2059-2067, 2003 | 1786 | 2003 |
| Comparison of MR/ultrasound fusion–guided biopsy with ultrasound-guided biopsy for the diagnosis of prostate cancer MM Siddiqui, S Rais-Bahrami, B Turkbey, AK George, J Rothwax, ... Jama 313 (4), 390-397, 2015 | 1649 | 2015 |
| Biochemical diagnosis of pheochromocytoma: which test is best? JWM Lenders, K Pacak, MCM Walther, WM Linehan, M Mannelli, ... Jama 287 (11), 1427-1434, 2002 | 1625 | 2002 |
| Machine learning identifies stemness features associated with oncogenic dedifferentiation TM Malta, A Sokolov, AJ Gentles, T Burzykowski, L Poisson, JN Weinstein, ... Cell 173 (2), 338-354. e15, 2018 | 1620 | 2018 |
| Reductive carboxylation supports growth in tumour cells with defective mitochondria AR Mullen, WW Wheaton, ES Jin, PH Chen, LB Sullivan, T Cheng, ... Nature 481 (7381), 385-388, 2012 | 1404 | 2012 |
| Regression of metastatic renal-cell carcinoma after nonmyeloablative allogeneic peripheral-blood stem-cell transplantation R Childs, A Chernoff, N Contentin, E Bahceci, D Schrump, S Leitman, ... New England Journal of Medicine 343 (11), 750-758, 2000 | 1335 | 2000 |
| Experience with the use of high-dose interleukin-2 in the treatment of 652 cancer patients SA Rosenberg, MT LOTZE, JC YANG, PM AEBERSOLD, WM Linehan, ... Annals of surgery 210 (4), 474-485, 1989 | 1318 | 1989 |
| HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability JS Isaacs, YJ Jung, DR Mole, S Lee, C Torres-Cabala, YL Chung, ... Cancer cell 8 (2), 143-153, 2005 | 1084 | 2005 |
| Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dube syndrome ML Nickerson, MB Warren, JR Toro, V Matrosova, G Glenn, ML Turner, ... Cancer cell 2 (2), 157-164, 2002 | 1021 | 2002 |
