Therapies for type 1 diabetes: current scenario and future perspectives V Pathak, NM Pathak, CL O’Neill, J Guduric-Fuchs, RJ Medina Clinical Medicine Insights: Endocrinology and Diabetes 12, 1179551419844521, 2019 | 128 | 2019 |
A novel CCK-8/GLP-1 hybrid peptide exhibiting prominent insulinotropic, glucose-lowering, and satiety actions with significant therapeutic potential in high-fat–fed mice N Irwin, V Pathak, PR Flatt Diabetes 64 (8), 2996-3009, 2015 | 83 | 2015 |
Metabolic and neuroprotective effects of dapagliflozin and liraglutide in diabetic mice P Millar, N Pathak, V Parthsarathy, AJ Bjourson, M O’Kane, V Pathak, ... Journal of Endocrinology 234 (3), 255-267, 2017 | 72 | 2017 |
Cholecystokinin (CCK) and related adjunct peptide therapies for the treatment of obesity and type 2 diabetes V Pathak, PR Flatt, N Irwin Peptides 100, 229-235, 2018 | 71 | 2018 |
Antagonism of gastric inhibitory polypeptide (GIP) by palmitoylation of GIP analogues with N-and C-terminal modifications improves obesity and metabolic control in high fat fed … V Pathak, VA Gault, PR Flatt, N Irwin Molecular and cellular endocrinology 401, 120-129, 2015 | 50 | 2015 |
Current concepts on endothelial stem cells definition, location, and markers SEJ Chambers, V Pathak, E Pedrini, L Soret, N Gendron, CL Guerin, ... Stem Cells Translational Medicine 10 (S2), S54-S61, 2021 | 41 | 2021 |
Sequential induction of beta cell rest and stimulation using stable GIP inhibitor and GLP-1 mimetic peptides improves metabolic control in C57BL/KsJ db/db mice V Pathak, S Vasu, VA Gault, PR Flatt, N Irwin Diabetologia 58, 2144-2153, 2015 | 37 | 2015 |
Novel dual incretin agonist peptide with antidiabetic and neuroprotective potential NM Pathak, V Pathak, VA Gault, S McClean, N Irwin, PR Flatt Biochemical Pharmacology 155, 264-274, 2018 | 35 | 2018 |
Characterisation of the biological activity of xenin-25 degradation fragment peptides CM Martin, V Parthsarathy, V Pathak, VA Gault, PR Flatt, N Irwin J Endocrinol 221 (2), 193-200, 2014 | 34 | 2014 |
Vascular regeneration for ischemic retinopathies: hope from cell therapies PM Bertelli, E Pedrini, J Guduric-Fuchs, E Peixoto, V Pathak, AW Stitt, ... Current eye research 45 (3), 372-384, 2020 | 26 | 2020 |
Beneficial metabolic actions of a stable GIP agonist following pre-treatment with a SGLT2 inhibitor in high fat fed diabetic mice PJB Millar, V Pathak, RC Moffett, NM Pathak, AJ Bjourson, MJ O'Kane, ... Molecular and Cellular Endocrinology 420, 37-45, 2016 | 26 | 2016 |
Stable oxyntomodulin analogues exert positive effects on hippocampal neurogenesis and gene expression as well as improving glucose homeostasis in high fat fed mice NM Pathak, V Pathak, AM Lynch, N Irwin, VA Gault, PR Flatt Molecular and cellular endocrinology 412, 95-103, 2015 | 26 | 2015 |
Long term high glucose exposure induces premature senescence in retinal endothelial cells PM Bertelli, E Pedrini, D Hughes, S McDonnell, V Pathak, E Peixoto, ... Frontiers in physiology 13, 929118, 2022 | 22 | 2022 |
A novel DPP IV-resistant C-terminally extended glucagon analogue exhibits weight-lowering and diabetes-protective effects in high-fat-fed mice mediated through glucagon and GLP … AM Lynch, N Pathak, V Pathak, FPM O’Harte, PR Flatt, N Irwin, VA Gault Diabetologia 57, 1927-1936, 2014 | 22 | 2014 |
Effects of chronic exposure of clonal β‐cells to elevated glucose and free fatty acids on incretin receptor gene expression and secretory responses to GIP and GLP‐1 V Pathak, S Vasu, PR Flatt, N Irwin Diabetes, Obesity and Metabolism 16 (4), 357-365, 2014 | 21 | 2014 |
Sustained treatment with a stable long‐acting oxyntomodulin analogue improves metabolic control and islet morphology in an experimental model of type 1 diabetes N Irwin, V Pathak, NM Pathak, VA Gault, PR Flatt Diabetes, Obesity and Metabolism 17 (9), 887-895, 2015 | 15 | 2015 |
Beneficial metabolic effects of dietary epigallocatechin gallate alone and in combination with exendin-4 in high fat diabetic mice NM Pathak, PJB Millar, V Pathak, PR Flatt, VA Gault Molecular and Cellular Endocrinology 460, 200-208, 2018 | 13 | 2018 |
The long pentraxin ptx3 as a new biomarker and pharmacological target in age-related macular degeneration and diabetic retinopathy M Stravalaci, M Ferrara, V Pathak, F Davi, B Bottazzi, A Mantovani, ... Frontiers in Pharmacology 12, 811344, 2022 | 12 | 2022 |
miR-130a activates the VEGFR2/STAT3/HIF1α axis to potentiate the vasoregenerative capacity of endothelial colony-forming cells in hypoxia J Guduric-Fuchs, E Pedrini, J Lechner, SEJ Chambers, CL O’Neill, ... Molecular Therapy-Nucleic Acids 23, 968-981, 2021 | 11 | 2021 |
Retinal pigment epithelium extracellular vesicles are potent inducers of age‐related macular degeneration disease phenotype in the outer retina M Kurzawa‐Akanbi, P Whitfield, F Burté, PM Bertelli, V Pathak, M Doherty, ... Journal of Extracellular Vesicles 11 (12), 12295, 2022 | 10 | 2022 |