Corticosterone primes the neuroinflammatory response to Gulf War Illness‐relevant organophosphates independently of acetylcholinesterase inhibition AR Locker, LT Michalovicz, KA Kelly, JV Miller, DB Miller, JP O'Callaghan Journal of neurochemistry 142 (3), 444-455, 2017 | 80 | 2017 |
Corticosterone potentiates DFP-induced neuroinflammation and affects high-order diffusion imaging in a rat model of Gulf War Illness BB Koo, LT Michalovicz, S Calderazzo, KA Kelly, K Sullivan, RJ Killiany, ... Brain, behavior, and immunity 67, 42-46, 2018 | 74 | 2018 |
The Leber congenital amaurosis protein, AIPL1, is needed for the viability and functioning of cone photoreceptor cells LT Kirschman, S Kolandaivelu, JM Frederick, L Dang, AFX Goldberg, ... Human molecular genetics 19 (6), 1076-1087, 2010 | 71 | 2010 |
Acetylcholinesterase inhibitor exposures as an initiating factor in the development of Gulf War Illness, a chronic neuroimmune disorder in deployed veterans LT Michalovicz, KA Kelly, K Sullivan, JP O'Callaghan Neuropharmacology 171, 108073, 2020 | 48 | 2020 |
Prior exposure to corticosterone markedly enhances and prolongs the neuroinflammatory response to systemic challenge with LPS KA Kelly, LT Michalovicz, JV Miller, V Castranova, DB Miller, ... PLoS one 13 (1), e0190546, 2018 | 48 | 2018 |
Corticosterone and pyridostigmine/DEET exposure attenuate peripheral cytokine expression: Supporting a dominant role for neuroinflammation in a mouse model of Gulf War Illness LT Michalovicz, AR Locker, KA Kelly, JV Miller, Z Barnes, MA Fletcher, ... Neurotoxicology 70, 26-32, 2019 | 46 | 2019 |
The neuroinflammatory phenotype in a mouse model of Gulf War Illness is unrelated to brain regional levels of acetylcholine as measured by quantitative HILIC-UPLC-MS/MS JV Miller, RF LeBouf, KA Kelly, LT Michalovicz, A Ranpara, AR Locker, ... Toxicological Sciences 165 (2), 302-313, 2018 | 41 | 2018 |
Epigenetic impacts of stress priming of the neuroinflammatory response to sarin surrogate in mice: a model of Gulf War illness DG Ashbrook, B Hing, LT Michalovicz, KA Kelly, JV Miller, WC de Vega, ... Journal of Neuroinflammation 15, 1-15, 2018 | 39 | 2018 |
Supporting a neuroimmune basis of Gulf War Illness JP O'Callaghan, LT Michalovicz, KA Kelly EBioMedicine 13, 5-6, 2016 | 28 | 2016 |
Astrocyte‐specific transcriptome analysis using the ALDH1L1 bacTRAP mouse reveals novel biomarkers of astrogliosis in response to neurotoxicity LT Michalovicz, KA Kelly, S Vashishtha, R Ben‐Hamo, S Efroni, JV Miller, ... Journal of Neurochemistry 150 (4), 420-440, 2019 | 24 | 2019 |
Oligodendrocyte involvement in gulf war illness J Belgrad, DJ Dutta, S Bromley‐Coolidge, KA Kelly, LT Michalovicz, ... Glia 67 (11), 2107-2124, 2019 | 23 | 2019 |
Alterations in high-order diffusion imaging in veterans with Gulf War Illness is associated with chemical weapons exposure and mild traumatic brain injury CH Cheng, BB Koo, S Calderazzo, E Quinn, K Aenlle, L Steele, N Klimas, ... Brain, behavior, and immunity 89, 281-290, 2020 | 21 | 2020 |
Corticosterone and exogenous glucose alter blood glucose levels, neurotoxicity, and vascular toxicity produced by methamphetamine JF Bowyer, KM Tranter, S Sarkar, NI George, JP Hanig, KA Kelly, ... Journal of neurochemistry 143 (2), 198-213, 2017 | 20 | 2017 |
Peripheral challenge with a viral mimic upregulates expression of the complement genes in the hippocampus LT Michalovicz, B Lally, GW Konat Journal of neuroimmunology 285, 137-142, 2015 | 17 | 2015 |
Peripherally restricted acute phase response to a viral mimic alters hippocampal gene expression LT Michalovicz, GW Konat Metabolic brain disease 29, 75-86, 2014 | 16 | 2014 |
Peripheral immune challenge with dsRNA enhances kainic acid-induced status epilepticus LT Kirschman, E Borysiewicz, D Fil, GW Konat Metabolic brain disease 26, 91-93, 2011 | 16 | 2011 |
TLR3 ligation protects human astrocytes against oxidative stress E Borysiewicz, S Doppalapudi, LT Kirschman, GW Konat Journal of neuroimmunology 255 (1-2), 54-59, 2013 | 14 | 2013 |
A logic model of neuronal-glial interaction suggests altered homeostatic regulation in the perpetuation of neuroinflammation TJA Craddock, LT Michalovicz, KA Kelly, MA Rice Jr, DB Miller, ... Frontiers in Cellular Neuroscience 12, 336, 2018 | 11 | 2018 |
The β-adrenergic receptor blocker and anti-inflammatory drug propranolol mitigates brain cytokine expression in a long-term model of Gulf War Illness LT Michalovicz, KA Kelly, DB Miller, K Sullivan, JP O'Callaghan Life sciences 285, 119962, 2021 | 9 | 2021 |
Modeling neuroimmune interactions in human subjects and animal models to predict subtype-specific multidrug treatments for gulf war illness FJ Carrera Arias, K Aenlle, M Abreu, MA Holschbach, LT Michalovicz, ... International journal of molecular sciences 22 (16), 8546, 2021 | 8 | 2021 |