Lrp4 is a receptor for Agrin and forms a complex with MuSK N Kim, AL Stiegler, TO Cameron, PT Hallock, AM Gomez, JH Huang, ... Cell 135 (2), 334-342, 2008 | 734 | 2008 |
Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation N Romberg, K Al Moussawi, C Nelson-Williams, AL Stiegler, E Loring, ... Nature genetics 46 (10), 1135-1139, 2014 | 507 | 2014 |
Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma S Zhao, M Choi, JD Overton, S Bellone, DM Roque, E Cocco, F Guzzo, ... Proceedings of the National Academy of Sciences 110 (8), 2916-2921, 2013 | 325 | 2013 |
EGFR-mutated lung cancer: a paradigm of molecular oncology Z Zhang, AL Stiegler, TJ Boggon, S Kobayashi, B Halmos Oncotarget 1 (7), 497, 2010 | 242 | 2010 |
Mutational landscape of uterine and ovarian carcinosarcomas implicates histone genes in epithelial–mesenchymal transition S Zhao, S Bellone, S Lopez, D Thakral, C Schwab, DP English, J Black, ... Proceedings of the National Academy of Sciences 113 (43), 12238-12243, 2016 | 210 | 2016 |
Mineralocorticoid receptor phosphorylation regulates ligand binding and renal response to volume depletion and hyperkalemia S Shibata, J Rinehart, J Zhang, G Moeckel, M Castañeda-Bueno, ... Cell metabolism 18 (5), 660-671, 2013 | 176 | 2013 |
Crystal structure of the agrin-responsive immunoglobulin-like domains 1 and 2 of the receptor tyrosine kinase MuSK AL Stiegler, SJ Burden, SR Hubbard Journal of molecular biology 364 (3), 424-433, 2006 | 89 | 2006 |
Crystal structure of the frizzled-like cysteine-rich domain of the receptor tyrosine kinase MuSK AL Stiegler, SJ Burden, SR Hubbard Journal of molecular biology 393 (1), 1-9, 2009 | 85 | 2009 |
Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension S Vilarinho, S Sari, G Yilmaz, AL Stiegler, TJ Boggon, D Jain, G Akyol, ... Hepatology 63 (6), 1977-1986, 2016 | 77 | 2016 |
Differences in binding to the ILK complex determines kindlin isoform adhesion localization and integrin activation C Huet-Calderwood, NN Brahme, N Kumar, AL Stiegler, S Raghavan, ... Journal of cell science 127 (19), 4308-4321, 2014 | 77 | 2014 |
Whole-exome sequencing of cervical carcinomas identifies activating ERBB2 and PIK3CA mutations as targets for combination therapy L Zammataro, S Lopez, S Bellone, F Pettinella, E Bonazzoli, E Perrone, ... Proceedings of the National Academy of Sciences 116 (45), 22730-22736, 2019 | 69 | 2019 |
Identification of PLX 4032‐resistance mechanisms and implications for novel RAF inhibitors J Choi, SF Landrette, T Wang, P Evans, A Bacchiocchi, R Bjornson, ... Pigment cell & melanoma research 27 (2), 253-262, 2014 | 59 | 2014 |
Structural basis for the disruption of the cerebral cavernous malformations 2 (CCM2) interaction with Krev interaction trapped 1 (KRIT1) by disease-associated mutations OS Fisher, W Liu, R Zhang, AL Stiegler, S Ghedia, JL Weber, TJ Boggon Journal of Biological Chemistry 290 (5), 2842-2853, 2015 | 43 | 2015 |
Mutations in ILK, encoding integrin-linked kinase, are associated with arrhythmogenic cardiomyopathy A Brodehl, S Rezazadeh, T Williams, NM Munsie, D Liedtke, T Oh, ... Translational Research 208, 15-29, 2019 | 42 | 2019 |
Structural basis for paxillin binding and focal adhesion targeting of β-parvin AL Stiegler, KM Draheim, X Li, NE Chayen, DA Calderwood, TJ Boggon Journal of Biological Chemistry 287 (39), 32566-32577, 2012 | 40 | 2012 |
Constrained chromatin accessibility in PU. 1-mutated agammaglobulinemia patients C Le Coz, DN Nguyen, C Su, BE Nolan, AV Albrecht, S Xhani, D Sun, ... Journal of Experimental Medicine 218 (7), e20201750, 2021 | 38 | 2021 |
Structural determinants for binding of sorting nexin 17 (SNX17) to the cytoplasmic adaptor protein Krev interaction trapped 1 (KRIT1) AL Stiegler, R Zhang, W Liu, TJ Boggon Journal of Biological Chemistry 289 (36), 25362-25373, 2014 | 33 | 2014 |
Structural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinase BP Chiswell, AL Stiegler, Z Razinia, E Nalibotski, TJ Boggon, ... Journal of structural biology 170 (1), 157-163, 2010 | 29 | 2010 |
p190RhoGAP proteins contain pseudoGTPase domains AL Stiegler, TJ Boggon Nature communications 8 (1), 506, 2017 | 24 | 2017 |
Purification and SAXS analysis of the integrin linked kinase, PINCH, parvin (IPP) heterotrimeric complex AL Stiegler, TD Grant, JR Luft, DA Calderwood, EH Snell, TJ Boggon PloS one 8 (1), e55591, 2013 | 21 | 2013 |