Discovery of highly potent benzimidazole derivatives as indoleamine 2, 3-dioxygenase-1 (IDO1) inhibitors: from structure-based virtual screening to in vivo pharmacodynamic activity M Serafini, E Torre, S Aprile, ED Grosso, A Gesù, A Griglio, G Colombo, ... Journal of medicinal chemistry 63 (6), 3047-3065, 2020 | 56 | 2020 |
Bioadhesive polymeric films based on red onion skins extract for wound treatment: An innovative and eco-friendly formulation C Pagano, M Marinozzi, C Baiocchi, T Beccari, P Calarco, MR Ceccarini, ... Molecules 25 (2), 318, 2020 | 40 | 2020 |
Kynurenine/tryptophan ratio as a potential blood-based biomarker in non-small cell lung cancer M Mandarano, E Orecchini, G Bellezza, J Vannucci, V Ludovini, S Baglivo, ... International journal of molecular sciences 22 (9), 4403, 2021 | 37 | 2021 |
Novel mutations in the WFS1 gene are associated with Wolfram syndrome and systemic inflammation E Panfili, G Mondanelli, C Orabona, ML Belladonna, M Gargaro, ... Human Molecular Genetics 30 (3-4), 265-276, 2021 | 28 | 2021 |
The immunosuppression pathway of tumor‐associated macrophages is controlled by heme oxygenase‐1 in glioblastoma patients S Magri, B Musca, L Pinton, E Orecchini, ML Belladonna, C Orabona, ... International Journal of Cancer 151 (12), 2265-2277, 2022 | 18 | 2022 |
Emulgel loaded with flaxseed extracts as new therapeutic approach in wound treatment C Pagano, C Baiocchi, T Beccari, F Blasi, L Cossignani, MR Ceccarini, ... Pharmaceutics 13 (8), 1107, 2021 | 18 | 2021 |
Effect of probiotic administration on serum tryptophan metabolites in pediatric type 1 diabetes patients G Mondanelli, E Orecchini, C Volpi, E Panfili, ML Belladonna, MT Pallotta, ... International Journal of Tryptophan Research 13, 1178646920956646, 2020 | 17 | 2020 |
Crocus sativus L. Petal Extract Inhibits Inflammation and Osteoclastogenesis in RAW 264.7 Cell Model C Orabona, E Orecchini, C Volpi, F Bacaloni, E Panfili, C Pagano, ... Pharmaceutics 14 (6), 1290, 2022 | 12 | 2022 |
Pathogenetic interplay between IL-6 and tryptophan metabolism in an experimental model of obesity G Mondanelli, E Albini, E Orecchini, MT Pallotta, ML Belladonna, G Ricci, ... Frontiers in Immunology 12, 713989, 2021 | 11 | 2021 |
The signaling function of IDO1 incites the malignant progression of mouse B16 melanoma E Orecchini, ML Belladonna, MT Pallotta, C Volpi, L Zizi, E Panfili, ... Oncoimmunology 12 (1), 2170095, 2023 | 10 | 2023 |
SLC6A4 DNA Methylation Levels and Serum Kynurenine/Tryptophan Ratio in Eating Disorders: A Possible Link with Psychopathological Traits? M Franzago, E Orecchini, A Porreca, G Mondanelli, C Orabona, ... Nutrients 15 (2), 406, 2023 | 9 | 2023 |
Artocarpus tonkinensis Extract Inhibits LPS-Triggered Inflammation Markers and Suppresses RANKL-Induced Osteoclastogenesis in RAW264.7 E Orecchini, G Mondanelli, C Orabona, C Volpi, S Adorisio, M Calvitti, ... Frontiers in Pharmacology 11, 593829, 2021 | 9 | 2021 |
Modulation of indoleamine 2, 3-dioxygenase 1 during inflammatory bowel disease activity in humans and mice E Proietti, RWM Pauwels, AC de Vries, E Orecchini, C Volpi, C Orabona, ... International Journal of Tryptophan Research 16, 11786469231153109, 2023 | 6 | 2023 |
The [1,2,4]Triazolo[4,3‐a]pyridine as a New Player in the Field of IDO1 Catalytic Holo‐Inhibitors S Fallarini, IP Bhela, S Aprile, E Torre, A Ranza, E Orecchini, E Panfili, ... ChemMedChem 16 (22), 3439-3450, 2021 | 4 | 2021 |
The circadian control of tryptophan metabolism regulates the host response to pulmonary fungal infections C Stincardini, M Pariano, F D’Onofrio, G Renga, E Orecchini, C Orabona, ... PNAS nexus 2 (3), pgad036, 2023 | 3 | 2023 |
Human Indoleamine 2, 3-dioxygenase 1 (IDO1) Expressed in Plant Cells Induces Kynurenine Production M Bellucci, A Pompa, C De Marcos Lousa, E Panfili, E Orecchini, ... International Journal of Molecular Sciences 22 (10), 5102, 2021 | 2 | 2021 |
Unrevealing the Role of TLRs in the Pathogenesis of Autoimmune Disease by Using Mouse Model of Diabetes E Panfili, E Orecchini, G Mondanelli Toll-Like Receptors: Methods and Protocols, 187-198, 2023 | | 2023 |
Anti-osteoclastogenic activity of Crocus sativus petal extract: turning saffron waste into a valuable resource against bone disruption. C Volpi, F Bacaloni, C Orabona, E Orecchini, E Panfili, C Pagano, ... XXII Congresso Nazionale CIRIAF-SVILUPPO SOSTENIBILE, TUTELA DELL’AMBIENTE E …, 2022 | | 2022 |