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Wilbert P. Vermeij
Wilbert P. Vermeij
Co-PI Genome Instability and Nutrition, Princess Maxima Center, Oncode Institute
在 prinsesmaximacentrum.nl 的电子邮件经过验证 - 首页
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Cellular senescence drives age-dependent hepatic steatosis
M Ogrodnik, S Miwa, T Tchkonia, D Tiniakos, CL Wilson, A Lahat, CP Day, ...
Nature communications 8 (1), 15691, 2017
8072017
Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice
WP Vermeij, MET Dollé, E Reiling, D Jaarsma, C Payan-Gomez, ...
Nature 537 (7620), 427-431, 2016
2812016
Akkermansia muciniphila ameliorates the age-related decline in colonic mucus thickness and attenuates immune activation in accelerated aging Ercc1−/Δ7 mice
B van der Lugt, AA Van Beek, S Aalvink, B Meijer, B Sovran, WP Vermeij, ...
Immunity & Ageing 16, 1-17, 2019
1722019
Chemotherapy side-effects: not all DNA damage is equal
WMC van den Boogaard, DSJ Komninos, WP Vermeij
Cancers 14 (3), 627, 2022
1382022
Genome integrity in aging: human syndromes, mouse models, and therapeutic options
WP Vermeij, JHJ Hoeijmakers, J Pothof
Annual review of pharmacology and toxicology 56 (1), 427-445, 2016
1372016
ROS quenching potential of the epidermal cornified cell envelope
WP Vermeij, A Alia, C Backendorf
Journal of Investigative Dermatology 131 (7), 1435-1441, 2011
1102011
Skin cornification proteins provide global link between ROS detoxification and cell migration during wound healing
WP Vermeij, C Backendorf
PloS one 5 (8), e11957, 2010
1012010
Menopause: genome stability as new paradigm
JSE Laven, JA Visser, AG Uitterlinden, WP Vermeij, JHJ Hoeijmakers
Maturitas 92, 15-23, 2016
732016
Aging: not all DNA damage is equal
WP Vermeij, JHJ Hoeijmakers, J Pothof
Current Opinion in Genetics & Development 26, 124-130, 2014
672014
Cell-autonomous progeroid changes in conditional mouse models for repair endonuclease XPG deficiency
S Barnhoorn, LM Uittenboogaard, D Jaarsma, WP Vermeij, M Tresini, ...
PLoS genetics 10 (10), e1004686, 2014
662014
Supplementation with Lactobacillus plantarum WCFS1 Prevents Decline of Mucus Barrier in Colon of Accelerated Aging Ercc1−/Δ7 Mice
AA van Beek, B Sovran, F Hugenholtz, B Meijer, JA Hoogerland, ...
Frontiers in immunology 7, 408, 2016
652016
DNA damage and transcription stress cause ATP-mediated redesign of metabolism and potentiation of anti-oxidant buffering
C Milanese, CR Bombardieri, S Sepe, S Barnhoorn, C Payán-Goméz, ...
Nature communications 10 (1), 4887, 2019
562019
Deficiency in the DNA repair protein ERCC1 triggers a link between senescence and apoptosis in human fibroblasts and mouse skin
DE Kim, MET Dollé, WP Vermeij, A Gyenis, K Vogel, JHJ Hoeijmakers, ...
Aging Cell 19 (3), e13072, 2020
542020
Distinct functional interactions of human Skn-1 isoforms with Ese-1 during keratinocyte terminal differentiation
A Cabral, DF Fischer, WP Vermeij, C Backendorf
Journal of Biological Chemistry 278 (20), 17792-17799, 2003
482003
Spatio-temporal analysis of molecular determinants of neuronal degeneration in the aging mouse cerebellum
EL de Graaf, WP Vermeij, MC de Waard, Y Rijksen, I van der Pluijm, ...
Molecular & Cellular Proteomics 12 (5), 1350-1362, 2013
382013
Unlike dietary restriction, rapamycin fails to extend lifespan and reduce transcription stress in progeroid DNA repair‐deficient mice
MB Birkisdóttir, D Jaarsma, RMC Brandt, S Barnhoorn, N van Vliet, ...
Aging Cell 20 (2), e13302, 2021
342021
Compression of morbidity in a progeroid mouse model through the attenuation of myostatin/activin signalling
K Alyodawi, WP Vermeij, S Omairi, O Kretz, M Hopkinson, F Solagna, ...
Journal of cachexia, sarcopenia and muscle 10 (3), 662-686, 2019
312019
Tissue-specific suppression of thyroid hormone signaling in various mouse models of aging
WE Visser, CR Bombardieri, C Zevenbergen, S Barnhoorn, A Ottaviani, ...
PLoS One 11 (3), e0149941, 2016
312016
Proteomic identification of in vivo interactors reveals novel function of skin cornification proteins
WP Vermeij, BI Florea, S Isenia, A Alia, J Brouwer, C Backendorf
Journal of Proteome Research 11 (6), 3068-3076, 2012
312012
Selective DNA damage responses in murine Xpa−/−, Xpc−/− and Csb−/− keratinocyte cultures
GJ Stout, M van Oosten, FZ Acherrat, J de Wit, WP Vermeij, ...
DNA repair 4 (11), 1337-1344, 2005
302005
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