Cellular senescence drives age-dependent hepatic steatosis M Ogrodnik, S Miwa, T Tchkonia, D Tiniakos, CL Wilson, A Lahat, CP Day, ... Nature communications 8 (1), 15691, 2017 | 807 | 2017 |
Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice WP Vermeij, MET Dollé, E Reiling, D Jaarsma, C Payan-Gomez, ... Nature 537 (7620), 427-431, 2016 | 281 | 2016 |
Akkermansia muciniphila ameliorates the age-related decline in colonic mucus thickness and attenuates immune activation in accelerated aging Ercc1−/Δ7 mice B van der Lugt, AA Van Beek, S Aalvink, B Meijer, B Sovran, WP Vermeij, ... Immunity & Ageing 16, 1-17, 2019 | 172 | 2019 |
Chemotherapy side-effects: not all DNA damage is equal WMC van den Boogaard, DSJ Komninos, WP Vermeij Cancers 14 (3), 627, 2022 | 138 | 2022 |
Genome integrity in aging: human syndromes, mouse models, and therapeutic options WP Vermeij, JHJ Hoeijmakers, J Pothof Annual review of pharmacology and toxicology 56 (1), 427-445, 2016 | 137 | 2016 |
ROS quenching potential of the epidermal cornified cell envelope WP Vermeij, A Alia, C Backendorf Journal of Investigative Dermatology 131 (7), 1435-1441, 2011 | 110 | 2011 |
Skin cornification proteins provide global link between ROS detoxification and cell migration during wound healing WP Vermeij, C Backendorf PloS one 5 (8), e11957, 2010 | 101 | 2010 |
Menopause: genome stability as new paradigm JSE Laven, JA Visser, AG Uitterlinden, WP Vermeij, JHJ Hoeijmakers Maturitas 92, 15-23, 2016 | 73 | 2016 |
Aging: not all DNA damage is equal WP Vermeij, JHJ Hoeijmakers, J Pothof Current Opinion in Genetics & Development 26, 124-130, 2014 | 67 | 2014 |
Cell-autonomous progeroid changes in conditional mouse models for repair endonuclease XPG deficiency S Barnhoorn, LM Uittenboogaard, D Jaarsma, WP Vermeij, M Tresini, ... PLoS genetics 10 (10), e1004686, 2014 | 66 | 2014 |
Supplementation with Lactobacillus plantarum WCFS1 Prevents Decline of Mucus Barrier in Colon of Accelerated Aging Ercc1−/Δ7 Mice AA van Beek, B Sovran, F Hugenholtz, B Meijer, JA Hoogerland, ... Frontiers in immunology 7, 408, 2016 | 65 | 2016 |
DNA damage and transcription stress cause ATP-mediated redesign of metabolism and potentiation of anti-oxidant buffering C Milanese, CR Bombardieri, S Sepe, S Barnhoorn, C Payán-Goméz, ... Nature communications 10 (1), 4887, 2019 | 56 | 2019 |
Deficiency in the DNA repair protein ERCC1 triggers a link between senescence and apoptosis in human fibroblasts and mouse skin DE Kim, MET Dollé, WP Vermeij, A Gyenis, K Vogel, JHJ Hoeijmakers, ... Aging Cell 19 (3), e13072, 2020 | 54 | 2020 |
Distinct functional interactions of human Skn-1 isoforms with Ese-1 during keratinocyte terminal differentiation A Cabral, DF Fischer, WP Vermeij, C Backendorf Journal of Biological Chemistry 278 (20), 17792-17799, 2003 | 48 | 2003 |
Spatio-temporal analysis of molecular determinants of neuronal degeneration in the aging mouse cerebellum EL de Graaf, WP Vermeij, MC de Waard, Y Rijksen, I van der Pluijm, ... Molecular & Cellular Proteomics 12 (5), 1350-1362, 2013 | 38 | 2013 |
Unlike dietary restriction, rapamycin fails to extend lifespan and reduce transcription stress in progeroid DNA repair‐deficient mice MB Birkisdóttir, D Jaarsma, RMC Brandt, S Barnhoorn, N van Vliet, ... Aging Cell 20 (2), e13302, 2021 | 34 | 2021 |
Compression of morbidity in a progeroid mouse model through the attenuation of myostatin/activin signalling K Alyodawi, WP Vermeij, S Omairi, O Kretz, M Hopkinson, F Solagna, ... Journal of cachexia, sarcopenia and muscle 10 (3), 662-686, 2019 | 31 | 2019 |
Tissue-specific suppression of thyroid hormone signaling in various mouse models of aging WE Visser, CR Bombardieri, C Zevenbergen, S Barnhoorn, A Ottaviani, ... PLoS One 11 (3), e0149941, 2016 | 31 | 2016 |
Proteomic identification of in vivo interactors reveals novel function of skin cornification proteins WP Vermeij, BI Florea, S Isenia, A Alia, J Brouwer, C Backendorf Journal of Proteome Research 11 (6), 3068-3076, 2012 | 31 | 2012 |
Selective DNA damage responses in murine Xpa−/−, Xpc−/− and Csb−/− keratinocyte cultures GJ Stout, M van Oosten, FZ Acherrat, J de Wit, WP Vermeij, ... DNA repair 4 (11), 1337-1344, 2005 | 30 | 2005 |