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Sujatha Muralidharan
Sujatha Muralidharan
Director, Translational Medicine
在 astrazeneca.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice
JJ Fuster, S MacLauchlan, MA Zuriaga, MN Polackal, AC Ostriker, ...
Science 355 (6327), 842-847, 2017
11752017
Cellular stress response and innate immune signaling: integrating pathways in host defense and inflammation
S Muralidharan, P Mandrekar
Journal of leukocyte biology 94 (6), 1167-1184, 2013
3462013
Moderate alcohol induces stress proteins HSF1 and hsp70 and inhibits proinflammatory cytokines resulting in endotoxin tolerance
S Muralidharan, A Ambade, MA Fulham, J Deshpande, D Catalano, ...
The Journal of Immunology 193 (4), 1975-1987, 2014
812014
Activation of Wnt signaling arrests effector differentiation in human peripheral and cord blood-derived T lymphocytes
S Muralidharan, PJ Hanley, E Liu, R Chakraborty, C Bollard, E Shpall, ...
The Journal of Immunology 187 (10), 5221-5232, 2011
742011
Low-dose radiation affects cardiac physiology: gene networks and molecular signaling in cardiomyocytes
MA Coleman, SP Sasi, J Onufrak, M Natarajan, K Manickam, J Schwab, ...
American Journal of Physiology-Heart and Circulatory Physiology 309 (11 …, 2015
562015
Blocking GM-CSF receptor α with mavrilimumab reduces infiltrating cells, pro-inflammatory markers and neoangiogenesis in ex vivo cultured arteries from patients with giant cell …
M Corbera-Bellalta, R Alba-Rovira, S Muralidharan, G Espígol-Frigolé, ...
Annals of the rheumatic diseases 81 (4), 524-536, 2022
322022
Human Binge Alcohol Intake Inhibits TLR4–MyD88 and TLR4–TRIF Responses but Not the TLR3–TRIF Pathway: HspA1A and PP1 Play Selective Regulatory Roles
S Muralidharan, A Lim, D Catalano, P Mandrekar
The Journal of Immunology 200 (7), 2291-2303, 2018
292018
THU0008 GM-CSF pathway signature identified in temporal artery biopsies of patients with giant cell arteritis
MC Cid, R Gandhi, M Corbera-Bellalta, S Muralidharan, JF Paolini
Annals of the Rheumatic Diseases 78 (Suppl 2), 271-272, 2019
192019
Anti-CD40 antibody KPL-404 inhibits T cell-mediated activation of B cells from healthy donors and autoimmune patients
J Marken, S Muralidharan, NV Giltiay
Arthritis research & therapy 23, 1-15, 2021
152021
Ionizing particle radiation as a modulator of endogenous bone marrow cell reprogramming: implications for hematological cancers
S Muralidharan, SP Sasi, MA Zuriaga, KK Hirschi, CD Porada, ...
Frontiers in oncology 5, 231, 2015
152015
BOXR1030, an anti-GPC3 CAR with exogenous GOT2 expression, shows enhanced T cell metabolism and improved anti-cell line derived tumor xenograft activity
TL Hickman, E Choi, KR Whiteman, S Muralidharan, T Pai, T Johnson, ...
PloS One 17 (5), 2022
142022
FRI0010 GM-CSFR pathway is implicated in pathogenic inflammatory mechanisms in giant cell arteritis
MC Cid, S Muralidharan, M Corbera-Bellalta, G Espigol-Frigole, ...
Annals of the Rheumatic Diseases 79 (Suppl 1), 576-576, 2020
92020
Particle radiation‐induced nontargeted effects in bone‐marrow‐derived endothelial progenitor cells
SP Sasi, D Park, S Muralidharan, J Wage, A Kiladjian, J Onufrak, ...
Stem Cells International 2015 (1), 496512, 2015
72015
Preclinical immunopharmacologic assessment of KPL-404, a novel, humanized, non-depleting antagonistic anti-CD40 monoclonal antibody
S Muralidharan, M Njenga, T Garron, K Bondensgaard, JF Paolini
Journal of Pharmacology and Experimental Therapeutics 381 (1), 12-21, 2022
62022
Reduction of transplant vasculopathy by intraoperative nucleic acid-based therapy in a mouse aortic allograft model
R Arif, M Franz, A Remes, M Zaradzki, M Hecker, M Karck, OJ Müller, ...
The Thoracic and cardiovascular surgeon 67 (06), 503-512, 2019
52019
Glypican-3 (GPC3) is associated with MCPyV-negative status and impaired outcome in Merkel cell carcinoma
S Muralidharan, T Kervarrec, GJ Weiss, M Samimi
Oncotarget 13, 960, 2022
22022
BOXR1030, an anti-GPC3 CAR with exogenous GOT2 expression, shows enhanced T cell metabolism and improved antitumor activity
TL Hickman, E Choi, KR Whiteman, S Muralidharan, T Pai, T Johnson, ...
bioRxiv, 2021.11. 17.469041, 2021
22021
238 Exogenous GOT2 in CAR-T cells improves metabolic function and preserves early memory T cell subsets
J Hinds, S Muralidharan, A Ranger, J Coccia, T Giordano, E Kuiper, ...
Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022
2022
Glypican-3 immunohistochemistry precision, validation, and prevalence in selected solid tumors to identify target populations for CAR T cell therapy
GJ Weiss, A Jensen-Smith, S Muralidharan
Cancer Research 82 (12), 2022
2022
Increased Expression of Oncostatin M Receptor β in Chronic Pruritic Diseases
R Gandhi, A De Benedetto, S Muralidharan, J Ring, I Torres, T Berger, ...
Journal of Investigative Dermatology 139 (9), S283-S283, 2019
2019
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