Sterol regulatory element–binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity Y Kidani, H Elsaesser, MB Hock, L Vergnes, KJ Williams, JP Argus, ... Nature immunology 14 (5), 489-499, 2013 | 494 | 2013 |
Limiting cholesterol biosynthetic flux spontaneously engages type I IFN signaling AG York, KJ Williams, JP Argus, QD Zhou, G Brar, L Vergnes, EE Gray, ... Cell 163 (7), 1716-1729, 2015 | 390 | 2015 |
Principles of dimer-specific gene regulation revealed by a comprehensive characterization of NF-κB family DNA binding T Siggers, AB Chang, A Teixeira, D Wong, KJ Williams, B Ahmed, ... Nature immunology 13 (1), 95-102, 2012 | 254 | 2012 |
FXR activation protects against NAFLD via bile-acid-dependent reductions in lipid absorption BL Clifford, LR Sedgeman, KJ Williams, P Morand, A Cheng, KE Jarrett, ... Cell metabolism 33 (8), 1671-1684. e4, 2021 | 231 | 2021 |
An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity KJ Williams, JP Argus, Y Zhu, MQ Wilks, BN Marbois, AG York, Y Kidani, ... Cancer research 73 (9), 2850-2862, 2013 | 200 | 2013 |
De-Repression of PDGFRβ Transcription Promotes Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in Glioblastoma Patients D Akhavan, AL Pourzia, AA Nourian, KJ Williams, D Nathanson, I Babic, ... Cancer discovery 3 (5), 534-547, 2013 | 149 | 2013 |
A c-Rel subdomain responsible for enhanced DNA-binding affinity and selective gene activation S Sanjabi, KJ Williams, S Saccani, L Zhou, A Hoffmann, G Ghosh, ... Genes & development 19 (18), 2138-2151, 2005 | 144 | 2005 |
Toll-like receptors induce signal-specific reprogramming of the macrophage lipidome WY Hsieh, QD Zhou, AG York, KJ Williams, PO Scumpia, ... Cell metabolism 32 (1), 128-143. e5, 2020 | 104 | 2020 |
Mitochondria-rough-ER contacts in the liver regulate systemic lipid homeostasis I Anastasia, N Ilacqua, A Raimondi, P Lemieux, R Ghandehari-Alavijeh, ... Cell reports 34 (11), 2021 | 95 | 2021 |
Immune inhibitory ligand CD200 induction by TLRs and NLRs limits macrophage activation to protect the host from meningococcal septicemia S Mukhopadhyay, A Plüddemann, JC Hoe, KJ Williams, A Varin, ... Cell host & microbe 8 (3), 236-247, 2010 | 92 | 2010 |
Interferon-mediated reprogramming of membrane cholesterol to evade bacterial toxins QD Zhou, X Chi, MS Lee, WY Hsieh, JJ Mkrtchyan, AC Feng, C He, ... Nature immunology 21 (7), 746-755, 2020 | 72 | 2020 |
Context-dependent regulation of ferroptosis sensitivity L Magtanong, GD Mueller, KJ Williams, M Billmann, K Chan, DA Armenta, ... Cell chemical biology 29 (9), 1409-1418. e6, 2022 | 70 | 2022 |
A DMS shotgun lipidomics workflow application to facilitate high-throughput, comprehensive lipidomics B Su, LF Bettcher, WY Hsieh, D Hornburg, MJ Pearson, N Blomberg, ... Journal of the American Society for Mass Spectrometry 32 (11), 2655-2663, 2021 | 61 | 2021 |
Fatostatin inhibits cancer cell proliferation by affecting mitotic microtubule spindle assembly and cell division AA Gholkar, K Cheung, KJ Williams, YC Lo, SA Hamideh, C Nnebe, ... Journal of Biological Chemistry 291 (33), 17001-17008, 2016 | 60 | 2016 |
Cross-laboratory standardization of preclinical lipidomics using differential mobility spectrometry and multiple reaction monitoring M Ghorasaini, Y Mohammed, J Adamski, L Bettcher, JA Bowden, ... Analytical Chemistry 93 (49), 16369-16378, 2021 | 56 | 2021 |
Resveratrol and para-coumarate serve as ring precursors for coenzyme Q biosynthesis [S] LX Xie, KJ Williams, CH He, E Weng, S Khong, TE Rose, O Kwon, ... Journal of lipid research 56 (4), 909-919, 2015 | 49 | 2015 |
CDKN2A deletion remodels lipid metabolism to prime glioblastoma for ferroptosis JK Minami, D Morrow, NA Bayley, EG Fernandez, JJ Salinas, C Tse, ... Cancer cell 41 (6), 1048-1060. e9, 2023 | 40 | 2023 |
Profiling of mouse macrophage lipidome using direct infusion shotgun mass spectrometry WY Hsieh, KJ Williams, B Su, SJ Bensinger STAR protocols 2 (1), 100235, 2021 | 35 | 2021 |
Transcriptional regulation of N6-methyladenosine orchestrates sex-dimorphic metabolic traits DA Salisbury, D Casero, Z Zhang, D Wang, J Kim, X Wu, L Vergnes, ... Nature metabolism 3 (7), 940-953, 2021 | 30 | 2021 |
Transintestinal transport of the anti-inflammatory drug 4F and the modulation of transintestinal cholesterol efflux [S] D Meriwether, D Sulaiman, A Wagner, V Grijalva, I Kaji, KJ Williams, L Yu, ... Journal of lipid research 57 (7), 1175-1193, 2016 | 27 | 2016 |