A conserved dendritic-cell regulatory program limits antitumour immunity B Maier, AM Leader, ST Chen, N Tung, C Chang, J LeBerichel, ... Nature 580 (7802), 257-262, 2020 | 663 | 2020 |
Mapping systemic inflammation and antibody responses in multisystem inflammatory syndrome in children (MIS-C) CN Gruber, RS Patel, R Trachtman, L Lepow, F Amanat, F Krammer, ... Cell 183 (4), 982-995. e14, 2020 | 585 | 2020 |
Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells M Casanova-Acebes, E Dalla, AM Leader, J LeBerichel, J Nikolic, ... Nature 595 (7868), 578-584, 2021 | 384 | 2021 |
Single-cell analysis of human non-small cell lung cancer lesions refines tumor classification and patient stratification AM Leader, JA Grout, BB Maier, BY Nabet, MD Park, A Tabachnikova, ... Cancer cell 39 (12), 1594-1609. e12, 2021 | 216 | 2021 |
Spatial positioning and matrix programs of cancer-associated fibroblasts promote T-cell exclusion in human lung tumors JA Grout, P Sirven, AM Leader, S Maskey, E Hector, I Puisieux, F Steffan, ... Cancer Discovery 12 (11), 2606-2625, 2022 | 134 | 2022 |
The interaction of CD4+ helper T cells with dendritic cells shapes the tumor microenvironment and immune checkpoint blockade response M Cohen, A Giladi, O Barboy, P Hamon, B Li, M Zada, A Gurevich-Shapiro, ... Nature cancer 3 (3), 303-317, 2022 | 125 | 2022 |
Spatial CRISPR genomics identifies regulators of the tumor microenvironment M Dhainaut, SA Rose, G Akturk, A Wroblewska, SR Nielsen, ES Park, ... Cell 185 (7), 1223-1239. e20, 2022 | 114 | 2022 |
Intratumoral dendritic cell–CD4+ T helper cell niches enable CD8+ T cell differentiation following PD-1 blockade in hepatocellular carcinoma A Magen, P Hamon, N Fiaschi, BY Soong, MD Park, R Mattiuz, E Humblin, ... Nature medicine 29 (6), 1389-1399, 2023 | 108 | 2023 |
TREM2 macrophages drive NK cell paucity and dysfunction in lung cancer MD Park, I Reyes-Torres, J LeBerichel, P Hamon, NM LaMarche, ... Nature immunology 24 (5), 792-801, 2023 | 70 | 2023 |
Downregulation of exhausted cytotoxic T cells in gene expression networks of multisystem inflammatory syndrome in children ND Beckmann, PH Comella, E Cheng, L Lepow, AG Beckmann, SR Tyler, ... Nature communications 12 (1), 4854, 2021 | 63 | 2021 |
BRAFV600E-induced senescence drives Langerhans cell histiocytosis pathophysiology C Bigenwald, J Le Berichel, CM Wilk, R Chakraborty, ST Chen, ... Nature medicine 27 (5), 851-861, 2021 | 55 | 2021 |
A shift in lung macrophage composition is associated with COVID-19 severity and recovery ST Chen, MD Park, DM Del Valle, M Buckup, A Tabachnikova, ... Science translational medicine 14 (662), eabn5168, 2022 | 50 | 2022 |
RXRs control serous macrophage neonatal expansion and identity and contribute to ovarian cancer progression M Casanova-Acebes, MP Menéndez-Gutiérrez, J Porcuna, ... Nature Communications 11 (1), 1655, 2020 | 43 | 2020 |
Molecular states during acute COVID-19 reveal distinct etiologies of long-term sequelae RC Thompson, NW Simons, L Wilkins, E Cheng, DM Del Valle, ... Nature Medicine 29 (1), 236-246, 2023 | 42 | 2023 |
An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis NM LaMarche, S Hegde, MD Park, BB Maier, L Troncoso, J Le Berichel, ... Nature 625 (7993), 166-174, 2024 | 36 | 2024 |
Interleukin-22-deficiency and microbiota contribute to the exacerbation of Toxoplasma gondii-induced intestinal inflammation A Couturier-Maillard, N Froux, J Piotet-Morin, C Michaudel, L Brault, ... Mucosal immunology 11 (4), 1181-1190, 2018 | 36 | 2018 |
Sampling the host response to SARS-CoV-2 in hospitals under siege AW Charney, NW Simons, K Mouskas, L Lepow, E Cheng, J Le Berichel, ... Nature Medicine 26 (8), 1157-1158, 2020 | 31 | 2020 |
IL‐1R1–MyD88 axis elicits papain‐induced lung inflammation R Agoro, J Piotet‐Morin, J Palomo, C Michaudel, S Vigne, I Maillet, ... European journal of immunology 46 (11), 2531-2541, 2016 | 31 | 2016 |
The probiotic strain Escherichia coli Nissle 1917 prevents papain-induced respiratory barrier injury and severe allergic inflammation in mice T Secher, I Maillet, C Mackowiak, J Le Bérichel, A Philippeau, C Panek, ... Scientific reports 8 (1), 11245, 2018 | 24 | 2018 |
Cytotoxic lymphocytes are dysregulated in multisystem inflammatory syndrome in children ND Beckmann, PH Comella, E Cheng, L Lepow, AG Beckmann, ... Medrxiv, 2020 | 15 | 2020 |