Karyopherins and nuclear import YM Chook, G Blobel Current opinion in structural biology 11 (6), 703-715, 2001 | 695 | 2001 |
Rules for nuclear localization sequence recognition by karyopherinβ2 BJ Lee, AE Cansizoglu, KE Süel, TH Louis, Z Zhang, YM Chook Cell 126 (3), 543-558, 2006 | 663 | 2006 |
Structure of the nuclear transport complex karyopherin-β2–Ran GppNHp YM Chook, G Blobel Nature 399 (6733), 230-237, 1999 | 487 | 1999 |
Nuclear import by karyopherin-βs: recognition and inhibition YM Chook, KE Süel Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (9), 1593-1606, 2011 | 468 | 2011 |
Nuclear-import receptors reverse aberrant phase transitions of RNA-binding proteins with prion-like domains L Guo, HJ Kim, H Wang, J Monaghan, F Freyermuth, JC Sung, ... Cell 173 (3), 677-692. e20, 2018 | 433 | 2018 |
Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia R Lapalombella, Q Sun, K Williams, L Tangeman, S Jha, Y Zhong, ... Blood, The Journal of the American Society of Hematology 120 (23), 4621-4634, 2012 | 378 | 2012 |
Structural basis for leucine-rich nuclear export signal recognition by CRM1 X Dong, A Biswas, KE Süel, LK Jackson, R Martinez, H Gu, YM Chook Nature 458 (7242), 1136-1141, 2009 | 354 | 2009 |
Nuclear import receptor inhibits phase separation of FUS through binding to multiple sites T Yoshizawa, R Ali, J Jiou, HYJ Fung, KA Burke, SJ Kim, Y Lin, ... Cell 173 (3), 693-705. e22, 2018 | 299 | 2018 |
Crystal structures of the monofunctional chorismate mutase from Bacillus subtilis and its complex with a transition state analog. YM Chook, H Ke, WN Lipscomb Proceedings of the National Academy of Sciences 90 (18), 8600-8603, 1993 | 278 | 1993 |
Recognition of nuclear targeting signals by Karyopherin-β proteins D Xu, A Farmer, YM Chook Current opinion in structural biology 20 (6), 782-790, 2010 | 252 | 2010 |
Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1 Q Sun, YP Carrasco, Y Hu, X Guo, H Mirzaei, J MacMillan, YM Chook Proceedings of the National Academy of Sciences 110 (4), 1303-1308, 2013 | 248 | 2013 |
The monofunctional chorismate mutase from Bacillus subtilis: structure determination of chorismate mutase and its complexes with a transition state analog and prephenate, and … YM Chook, JV Gray, H Ke, WN Lipscomb Journal of molecular biology 240 (5), 476-500, 1994 | 229 | 1994 |
Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cells J Etchin, Q Sun, A Kentsis, A Farmer, ZC Zhang, T Sanda, MR Mansour, ... Leukemia 27 (1), 66-74, 2013 | 205 | 2013 |
NESdb: a database of NES-containing CRM1 cargoes D Xu, NV Grishin, YM Chook Molecular biology of the cell 23 (18), 3673-3676, 2012 | 195 | 2012 |
Structure-based design of a pathway-specific nuclear import inhibitor AE Cansizoglu, BJ Lee, ZC Zhang, BMA Fontoura, YM Chook Nature structural & molecular biology 14 (5), 452-454, 2007 | 183 | 2007 |
Nuclear localization signals for four distinct karyopherin-β nuclear import systems M Soniat, YM Chook Biochemical Journal 468 (3), 353-362, 2015 | 174 | 2015 |
Sequence and structural analyses of nuclear export signals in the NESdb database D Xu, A Farmer, G Collett, NV Grishin, YM Chook Molecular biology of the cell 23 (18), 3677-3693, 2012 | 174 | 2012 |
Structural and energetic basis of ALS-causing mutations in the atypical proline–tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS) ZC Zhang, YM Chook Proceedings of the National Academy of Sciences 109 (30), 12017-12021, 2012 | 164 | 2012 |
Atomic basis of CRM1-cargo recognition, release and inhibition HYJ Fung, YM Chook Seminars in cancer biology 27, 52-61, 2014 | 158 | 2014 |
LocNES: a computational tool for locating classical NESs in CRM1 cargo proteins D Xu, K Marquis, J Pei, SC Fu, T Cağatay, NV Grishin, YM Chook Bioinformatics 31 (9), 1357-1365, 2015 | 154 | 2015 |