Next generation physiologically based kinetic (NG-PBK) models in support of regulatory decision making A Paini, JA Leonard, E Joossens, JGM Bessems, A Desalegn, JL Dorne, ... Computational Toxicology 9, 61-72, 2019 | 103 | 2019 |
Effective exposure of chemicals in in vitro cell systems: A review of chemical distribution models S Proença, BI Escher, FC Fischer, C Fisher, S Grégoire, NJ Hewitt, B Nicol, ... Toxicology in Vitro 73, 105133, 2021 | 52 | 2021 |
Insights into in vitro biokinetics using Virtual Cell Based Assay simulations S Proença, A Paini, E Joossens, JVS Benito, E Berggren, A Worth, ... ALTEX-Alternatives to animal experimentation 36 (3), 447-461, 2019 | 12 | 2019 |
EURL ECVAM Workshop on new generation of physiologically-based kinetic models in risk assessment A Paini, E Joossens, J Bessems, A Desalegn, JL Dorne, JP Gosling, ... Publications Office of the European Union, 2017 | 12 | 2017 |
Insights into PCDD/Fs and PAHs in biomass boilers envisaging risks of ash use as fertilizers H Lopes, S Proença Applied Sciences 10 (14), 4951, 2020 | 9 | 2020 |
EURL ECVAM workshop on new generation of physiologically-based kinetic models in risk assessment (2017) A Paini, E Joossens, J Bessems, A Desalegn, JL Dorne, JP Gosling, ... | 7 | |
Hipsc-derived hepatocyte-like cells can be used as a model for transcriptomics-based study of chemical toxicity S Ghosh, J De Smedt, T Tricot, S Proença, M Kumar, F Nami, ... Toxics 10 (1), 1, 2021 | 5 | 2021 |
Effective Exposure of Chemicals in S Proença, BI Escher, FC Fischer, C Fisher, S Grégoire, NJ Hewitt Vitro, 2021 | 5 | 2021 |
Impact of the SOD mimic MnTnHex-2-PyP on the adhesion and migration of doxorubicin-treated MDA-MB-231 cells A Florido, N Saraiva, S Cerqueira, I Batinic-Haberle, S Proença, ... Toxicology Letters 2 (238), S241-S242, 2015 | 4 | 2015 |
Pyridine-containing macrocycles display MMP-2/9 inhibitory activity and distinct effects on migration and invasion of 2D and 3D breast cancer models S Proença, B Antunes, RC Guedes, F Ramilo-Gomes, MF Cabral, J Costa, ... International Journal of Molecular Sciences 20 (20), 5109, 2019 | 3 | 2019 |
Next generation physiologically based kinetic (NG-PBK) models in support of regulatory decision making. Computational toxicology (Amsterdam, Netherlands) 9, 61–72 A Paini, JA Leonard, E Joossens, J Bessems, A Desalegn, JL Dorne, ... | 3 | 2019 |
Drug metabolism of hepatocyte-like organoids and their applicability in in vitro toxicity testing MC Bouwmeester, Y Tao, S Proença, FG van Steenbeek, RA Samsom, ... Molecules 28 (2), 621, 2023 | 1 | 2023 |
Application of the Virtual Cell Based Assay for Simulation of in vitro Chemical fate following Acute Exposure S Proenca, A Paini, E Joossens, JV Sala Benito, E Berggren, A Worth, ... JRC technical reports, European Union, 2017 | 1 | 2017 |
The effects of hexabromocyclododecane on the transcriptome and hepatic enzyme activity in three human HepaRG-based models S Proença, N van Sabben, J Legler, JH Kamstra, NI Kramer Toxicology 485, 153411, 2023 | | 2023 |
Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity in vitro using human BrainSpheres: a case study on amiodarone C Nunes, S Proença, G Ambrosini, D Pamies, A Thomas, NI Kramer, ... Frontiers in Pharmacology 14, 2023 | | 2023 |
S-28-01 Characterising applicability domains of generic in vitro distribution kinetic and physiologically based kinetic models N Kramer, A Paini, S Proenca, R Geci, H Yang, S Schaller Toxicology Letters 368, S68, 2022 | | 2022 |
Evaluation of renal and hepatic metabolism of short chain and long chain parabens in in vitro systems. L Capinha, F Dohmen, S Proenca, N Kramer, J Commandeur, P Jennings TOXICOLOGY LETTERS 314, S175-S175, 2019 | | 2019 |
Effects on migration of breast cancer cells in 3D models upon MMP inhibition SDLM Proença | | 2016 |
Effect of MMP inhibitors on the migration of breast cancer cells S Proença, M Cipriano, MF Cabral, J Costa, AS Fernandes, M Castro, ... Toxicology Letters, S141-S142, 2016 | | 2016 |
P11-018 A Flórido, N Saraiva, S Cerqueira, I Batinic-Haberle, S Proenca, ... Abstracts/Toxicology Letters 238S 56, S383, 2015 | | 2015 |