The acidic tumor microenvironment as a driver of cancer E Boedtkjer, SF Pedersen Annual review of physiology 82 (1), 103-126, 2020 | 713 | 2020 |
Physiology, pharmacology and pathophysiology of the pH regulatory transport proteins NHE1 and NBCn1: similarities, differences, and implications for cancer therapy E Boedtkjer, L Bunch, S F Pedersen Current pharmaceutical design 18 (10), 1345-1371, 2012 | 154 | 2012 |
Regulation and roles of bicarbonate transporters in cancer A Gorbatenko, CW Olesen, E Boedtkjer, SF Pedersen Frontiers in physiology 5, 130, 2014 | 147 | 2014 |
Disruption of Na+, HCO3− Cotransporter NBCn1 (slc4a7) Inhibits NO-Mediated Vasorelaxation, Smooth Muscle Ca2+ Sensitivity, and Hypertension Development in Mice E Boedtkjer, J Praetorius, VV Matchkov, E Stankevicius, S Mogensen, ... Circulation 124 (17), 1819-1829, 2011 | 145 | 2011 |
Contribution of Na+,HCO3−‐cotransport to cellular pH control in human breast cancer: A role for the breast cancer susceptibility locus NBCn1 (SLC4A7) E Boedtkjer, JMA Moreira, M Mele, P Vahl, VT Wielenga, PM Christiansen, ... International journal of cancer 132 (6), 1288-1299, 2013 | 129 | 2013 |
NBCn1 and NHE1 expression and activity in ΔNErbB2 receptor-expressing MCF-7 breast cancer cells: contributions to pHi regulation and chemotherapy resistance G Lauritzen, MBF Jensen, E Boedtkjer, R Dybboe, C Aalkjær, ... Experimental cell research 316 (15), 2538-2553, 2010 | 123 | 2010 |
Antibody-independent localization of the electroneutral Na+-HCO3− cotransporter NBCn1 (slc4a7) in mice E Boedtkjer, J Praetorius, EM Fuchtbauer, C Aalkjaer American Journal of Physiology-Cell Physiology 294 (2), C591-C603, 2008 | 94 | 2008 |
NBCn1 (slc4a7) Mediates the Na+-Dependent Bicarbonate Transport Important for Regulation of Intracellular pH in Mouse Vascular Smooth Muscle Cells E Boedtkjer, J Praetorius, C Aalkjaer Circulation research 98 (4), 515-523, 2006 | 92 | 2006 |
Disrupting Na+,HCO3–-cotransporter NBCn1 (Slc4a7) delays murine breast cancer development S Lee, TV Axelsen, AP Andersen, P Vahl, SF Pedersen, E Boedtkjer Oncogene, 2015 | 84 | 2015 |
The net acid extruders NHE1, NBCn1 and MCT4 promote mammary tumor growth through distinct but overlapping mechanisms AP Andersen, J Samsøe‐Petersen, EK Oernbo, E Boedtkjer, JMA Moreira, ... International journal of cancer 142 (12), 2529-2542, 2018 | 67 | 2018 |
Opening of small and intermediate calcium-activated potassium channels induces relaxation mainly mediated by nitric-oxide release in large arteries and endothelium-derived … E Stankevičius, T Dalsgaard, C Kroigaard, L Beck, E Boedtkjer, ... Journal of Pharmacology and Experimental Therapeutics 339 (3), 842-850, 2011 | 67 | 2011 |
Intracellular pH in the resistance vasculature: regulation and functional implications E Boedtkjer, C Aalkjaer Journal of vascular research 49 (6), 479-496, 2012 | 63 | 2012 |
Na+,HCO3 −-cotransport is functionally upregulated during human breast carcinogenesis and required for the inverted pH gradient across the plasma … S Lee, M Mele, P Vahl, PM Christiansen, VED Jensen, E Boedtkjer Pflügers Archiv-European Journal of Physiology 467, 367-377, 2015 | 60 | 2015 |
NHE1 knockout reduces blood pressure and arterial media/lumen ratio with no effect on resting pHi in the vascular wall E Boedtkjer, HH Damkier, C Aalkjaer The Journal of physiology 590 (8), 1895-1906, 2012 | 57 | 2012 |
Cation‐coupled bicarbonate transporters C Aalkjaer, E Boedtkjer, I Choi, S Lee Comprehensive Physiology 4 (4), 1605-1637, 2014 | 56 | 2014 |
Vasomotion has chloride-dependency in rat mesenteric small arteries DMB Boedtkjer, VV Matchkov, E Bødtkjer, H Nilsson, C Aalkjaer Pflügers Archiv-European Journal of Physiology 457, 389-404, 2008 | 53 | 2008 |
Extracellular HCO3- is sensed by mouse cerebral arteries: Regulation of tone by receptor protein tyrosine phosphatase γ E Boedtkjer, KB Hansen, DMB Boedtkjer, C Aalkjaer, WF Boron Journal of Cerebral Blood Flow & Metabolism, 0271678X15610787, 2015 | 50* | 2015 |
Na+,HCO3−-cotransporter NBCn1 increases pHi gradients, filopodia, and migration of smooth muscle cells and promotes arterial remodelling E Boedtkjer, JF Bentzon, VS Dam, C Aalkjaer Cardiovascular research 111 (3), 227-239, 2016 | 47 | 2016 |
Insulin inhibits Na+/H+ exchange in vascular smooth muscle and endothelial cells in situ: involvement of H2O2 and tyrosine phosphatase SHP-2 E Boedtkjer, C Aalkjaer American Journal of Physiology-Heart and Circulatory Physiology 296 (2 …, 2009 | 45 | 2009 |
Acid–base regulation and sensing: Accelerators and brakes in metabolic regulation of cerebrovascular tone E Boedtkjer Journal of Cerebral Blood Flow & Metabolism 38 (4), 588-602, 2018 | 43 | 2018 |