Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ... Nature genetics 45 (12), 1452-1458, 2013 | 4398 | 2013 |
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2248 | 2019 |
Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis WJ Jansen, R Ossenkoppele, DL Knol, BM Tijms, P Scheltens, ... Jama 313 (19), 1924-1938, 2015 | 1531 | 2015 |
New insights into the genetic etiology of Alzheimer’s disease and related dementias C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ... Nature genetics 54 (4), 412-436, 2022 | 994 | 2022 |
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 917 | 2017 |
TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis G Kleinberger, Y Yamanishi, M Suárez-Calvet, E Czirr, E Lohmann, ... Science translational medicine 6 (243), 243ra86-243ra86, 2014 | 749 | 2014 |
Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis R Ossenkoppele, WJ Jansen, GD Rabinovici, DL Knol, WM van der Flier, ... Jama 313 (19), 1939-1950, 2015 | 628 | 2015 |
Current pharmacotherapy for Alzheimer's disease A Lleo, SM Greenberg, JH Growdon Annu. Rev. Med. 57 (1), 513-533, 2006 | 502 | 2006 |
sTREM 2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early‐stage Alzheimer's disease and associate with neuronal injury markers M Suárez‐Calvet, G Kleinberger, MÁ Araque Caballero, M Brendel, ... EMBO molecular medicine 8 (5), 466-476, 2016 | 460 | 2016 |
A novel GSK-3β inhibitor reduces Alzheimer's pathology and rescues neuronal loss in vivo L Serenó, M Coma, M Rodriguez, P Sánchez-Ferrer, MB Sánchez, I Gich, ... Neurobiology of disease 35 (3), 359-367, 2009 | 417 | 2009 |
CSF biomarker variability in the Alzheimer's Association quality control program N Mattsson, U Andreasson, S Persson, MC Carrillo, S Collins, S Chalbot, ... Alzheimer's & Dementia 9 (3), 251-261, 2013 | 396 | 2013 |
Frontotemporal dementia and its subtypes: a genome-wide association study R Ferrari, DG Hernandez, MA Nalls, JD Rohrer, A Ramasamy, JBJ Kwok, ... The Lancet Neurology 13 (7), 686-699, 2014 | 383 | 2014 |
Consensus guidelines for lumbar puncture in patients with neurological diseases S Engelborghs, E Niemantsverdriet, H Struyfs, K Blennow, R Brouns, ... Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 8, 111-126, 2017 | 325 | 2017 |
A multicentre validation study of the diagnostic value of plasma neurofilament light NJ Ashton, S Janelidze, A Al Khleifat, A Leuzy, EL van der Ende, ... Nature communications 12 (1), 3400, 2021 | 295 | 2021 |
European Alzheimer’s Disease Initiative (EADI); Genetic and Environmental Risk in Alzheimer’s Disease; Alzheimer’s Disease Genetic Consortium; Cohorts for Heart and Aging … JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ... Nat Genet 45 (12), 1452-1458, 2013 | 292 | 2013 |
A novel Alzheimer disease locus located near the gene encoding tau protein G Jun, CA Ibrahim-Verbaas, M Vronskaya, JC Lambert, J Chung, AC Naj, ... Molecular psychiatry 21 (1), 108-117, 2016 | 289 | 2016 |
Nonsteroidal anti-inflammatory drugs lower Aβ42 and change presenilin 1 conformation A Lleó, O Berezovska, L Herl, S Raju, A Deng, BJ Bacskai, MP Frosch, ... Nature medicine 10 (10), 1065-1066, 2004 | 281 | 2004 |
Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World … P Lewczuk, P Riederer, SE O’bryant, MM Verbeek, B Dubois, PJ Visser, ... The world journal of biological psychiatry 19 (4), 244-328, 2018 | 252 | 2018 |
Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APP RJ Guerreiro, M Baquero, R Blesa, M Boada, JM Brás, MJ Bullido, ... Neurobiology of aging 31 (5), 725-731, 2010 | 252 | 2010 |
Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study R Guerreiro, OA Ross, C Kun-Rodrigues, DG Hernandez, T Orme, ... The Lancet Neurology 17 (1), 64-74, 2018 | 242 | 2018 |